Clinical characteristics of familial exudative vitreoretinopathy associated rhegmatogenous retinal detachment_Chinese Journal of Ocular Fundus Diseases

Authors：

YangYu , YuanMiner , LiZijing , 刘芳 , 占宗议 , 唐妙 , 潘间英 ,  丁小燕

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-San University, Guangzhou 510060, China;

Corresponding author：

丁小燕, Email: dingxy75@gmail.com

Keywords：

Retinal diseases/congenital; Retinal detachment/diagnosis; Fluorescein angiography; Diagnostic imaging

DOI：

10.3760/cma.j.issn.1005-1015.2015.03.012

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the clinical characteristics and surgical management of the familial exudative vitreoretinopathy (FEVR)-associated rhegmatogenous retinal detachment (RRD). Methods Retrospective noncomparative case series. Thirty-three eye of 32 patients were diagnosed FEVR-associated RRD by Fluorescein fundus angiography. There were 26 males and 6 females. The male to female ratio is 4.3:1 with an average age of 19.35±8.83 years. The detection of best corrected visual acuity (BCVA), refraction status, fundus photograph and fluorescein fundus angiography(FFA)were underwent in all patients. FEVR was confirmedby FFA and positive family history. The BCVA, refraction status, morphology of retinal detachment, location, size and shape of retinal hole, presence and grade of proliferative vitreoretinopathy (PVR), and subretinal proliferation were recorded. Results As for the refractive status, the scope of refraction was +2.0 D to-13.0 D andthe BCVA were range from light perception to 0.7. Atrophy holes which located at the temporal half were responsible for retinal detachment in all cases. Besides, horseshoe tears were noted in 6 eyes (18.18%), while macular tears were noted in 2 eyes of RRD (6.06%). The PVR greater than stage C2 was noticed in 10 eyes (30.30%), while subretinal proliferation was presented in 23 eyes (69.70%). Conclusions Male predominance, juvenile onset and associated with moderate to high myopia are the main characteristics in FEVR-associated RRD. Atrophy holes at the temporal half and the subretinal proliferations were most commonly in FEVR-associated RRD. Detailed fuduns and FFA examination of the fellow eye should be undergone to avoid misdiagnosis.

Citation： YangYu, YuanMiner, LiZijing. Clinical characteristics of familial exudative vitreoretinopathy associated rhegmatogenous retinal detachment. Chinese Journal of Ocular Fundus Diseases, 2015, 31(3): 260-262. doi: 10.3760/cma.j.issn.1005-1015.2015.03.012 Copy

1.	Criswick VG, Schepens CL. Familial exudative vitreoretinopathy[J]. Am J Ophthalmol, 1969, 68(4):578-594.
2.	Gow J, Oliver GL. Familial exudative vitreoretinopathy:an expanded view[J]. Arch Ophthalmol, 1971, 86(2):150-155.
3.	Pendergast SD, Trese MT. Familial exudative vitreoretinopathy:results of surgical management[J]. Ophthalmology, 1998, 105(6):1015-1023.
4.	Ikeda T, Fujikado T, Tano Y, et al. Vitrectomy for rhegmatogenous or tractional retinal detachment with familial exudative vitreoretinopathy[J]. Ophthalmology, 1999, 106(6):1081-1085.
5.	Chen SN, Hwang JF, Lin CJ. Clinical characteristics and surgical management of familial exudative vitreoretinopathy-associated rhegmatogenous retinal detachment[J]. Retina, 2012, 32(2):220-225.
6.	田超伟, 王雨生, 苏晓娜, 等.巩膜外垫压术治疗家族性渗出性玻璃体视网膜病变合并孔源性视网膜脱离[J].临床眼科杂志, 2013, 21(6):484-486.
7.	Canny CL, Oliver GL. Fluorescein angiographic findings in familial exudative vitreoretinopathy[J]. Arch Ophthalmol, 1976, 94(7):1114-1120.
8.	Ranchod TM, Ho LY, Drenser KA, et al. Clinical presentation of familial exudative vitreoretinopathy[J]. Ophthalmology, 2011, 118(10):2070-2075.
9.	张琦, 赵培泉, 蔡璇, 等.家族性渗出性玻璃体视网膜病变的临床特征[J].中华眼底病杂志, 2014, 30(4):374-377.
10.	杨文杰, 张琦, 赵培泉.家族性渗出性玻璃体视网膜病变致病基因及信号传导途径[J].中华眼底病杂志, 2011, 27(5):497-499.
11.	Gilmour DF. Familial exudative vitreoretinopathy and related retinopathies[J]. Eye (Lond), 2015, 29(1):1-14.

1. Criswick VG, Schepens CL. Familial exudative vitreoretinopathy[J]. Am J Ophthalmol, 1969, 68(4):578-594.
2. Gow J, Oliver GL. Familial exudative vitreoretinopathy:an expanded view[J]. Arch Ophthalmol, 1971, 86(2):150-155.
3. Pendergast SD, Trese MT. Familial exudative vitreoretinopathy:results of surgical management[J]. Ophthalmology, 1998, 105(6):1015-1023.
4. Ikeda T, Fujikado T, Tano Y, et al. Vitrectomy for rhegmatogenous or tractional retinal detachment with familial exudative vitreoretinopathy[J]. Ophthalmology, 1999, 106(6):1081-1085.
5. Chen SN, Hwang JF, Lin CJ. Clinical characteristics and surgical management of familial exudative vitreoretinopathy-associated rhegmatogenous retinal detachment[J]. Retina, 2012, 32(2):220-225.
6. 田超伟, 王雨生, 苏晓娜, 等.巩膜外垫压术治疗家族性渗出性玻璃体视网膜病变合并孔源性视网膜脱离[J].临床眼科杂志, 2013, 21(6):484-486.
7. Canny CL, Oliver GL. Fluorescein angiographic findings in familial exudative vitreoretinopathy[J]. Arch Ophthalmol, 1976, 94(7):1114-1120.
8. Ranchod TM, Ho LY, Drenser KA, et al. Clinical presentation of familial exudative vitreoretinopathy[J]. Ophthalmology, 2011, 118(10):2070-2075.
9. 张琦, 赵培泉, 蔡璇, 等.家族性渗出性玻璃体视网膜病变的临床特征[J].中华眼底病杂志, 2014, 30(4):374-377.
10. 杨文杰, 张琦, 赵培泉.家族性渗出性玻璃体视网膜病变致病基因及信号传导途径[J].中华眼底病杂志, 2011, 27(5):497-499.
11. Gilmour DF. Familial exudative vitreoretinopathy and related retinopathies[J]. Eye (Lond), 2015, 29(1):1-14.

Chinese Journal of Ocular Fundus Diseases

Clinical characteristics of familial exudative vitreoretinopathy associated rhegmatogenous retinal detachment

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content