Analysis of Relative Factors Influencing Electroencephalogram Seizure Duration during Modified Electroconvulsive Therapy_West China Medical Journal

Authors：

West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

Keywords：

改良电休克; 异丙酚; 脑电抽搐时间; 动态阻抗; 静态阻抗

DOI：

10.7507/1002-0179.20130230

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目的　探讨改良电休克治疗（MECT）中影响脑电抽搐时间的因素。方法　回顾性分析2011年10月－2011年12月经MECT的111例精神障碍患者的临床资料，利用Pearson相关分析方法进行统计，分析异丙酚用量、性别、设定电量、动态阻抗等因素对脑电抽搐时间的影响。结果　男性异丙酚用量平均值大于女性。女性的年龄、能量设定百分比、静态阻抗、动态阻抗均大于男性。与抽搐发作时间相关的因素是年龄、设定能量百分比。异丙酚剂量与脑电抽搐时间无相关。以脑电抽搐时间≥25 s为判定标准，男性的反应率高于女性。结论　行MECT时，需考虑患者年龄对发作时间的影响，异丙酚可安全用于MECT中。

Citation： MU Jie,WANG Rurong.. Analysis of Relative Factors Influencing Electroencephalogram Seizure Duration during Modified Electroconvulsive Therapy. West China Medical Journal, 2013, 28(5): 746-748. doi: 10.7507/1002-0179.20130230 Copy

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8.	Coffey CE, Lucke J, Weiner RD, et al. Seizure threshold in electroconvulsive therapy：I. Initial seizure threshold[J]. Biol Psychiatry, 1995, 37(10): 713-720.
9.	毛洪京, 骆宏, 陈树林, 等. 导致改良电休克治疗发作不良因素分析[J]. 浙江临床医学, 2007, 9(5): 683-684.
10.	Rasmussen K. The practice of electroconvulsive therapy: recommendations for treatment, training, and privileging[J]. J ECT, 2002, 18(1): 58-59.
11.	Stevens A, Fischer A, Bartels M, et al. Electroconvulsive therapy: a review on indications, methods, risks and medication[J]. Eur Psychiatry, 1996, 11(4): 165-174.
12.	Chung KF. Relationships between seizure duration and seizure threshold and stimulus dosage at electroconvulsive therapy: implications for electroconvulsive therapy practice[J]. Psychiatry Clin Neurosci, 2002, 56(5): 521-526.
13.	van Waarde JA, van der Mast RC. Seizure thresholds in elderly patients treated with electroconvulsive therapy for major depressive disorder: a review[J]. Curr Psychiatry Rev, 2010, 6(3): 184-190.
14.	van Waarde JA, van Oudheusden LJ, Verwey B, et al. Clinical predictors of seizure threshold in electroconvulsive therapy: a prospective study[J]. Eur Arch Psychiatry Clinc Neurosci, 2013, 263(2): 167-175.
15.	Shapira B, Lidsky D, Gorfine, M, et a1. Electroconvulsive therapy and resistant depression:clinical implications of seizure threshold[J]. J Clin Psychiatry, 1996, 57(1): 32-38．.

1. 　张新凯, 翁巍骏, 卢虹, 等. 电抽搐治疗精神疾病的发现与发展简史[ J]. 中华医史杂志, 2001, 3(4): 213- 216.
2. 　冯鹏玖, 蒋宗滨, 黄剑锋, 等. 不同剂量丙泊酚对电休克治疗患者心血管反应和癫痫发作的影响[J]. 广西医学, 2007, 28(11): 1769-1771.
3. 　Ding Z, White PF. Anesthesia for electroconvulsive therapy[J]. Anesth Analg, 2002, 94(5): 1351-1364.
4. 　苏洁, 陈奋莺. 丙泊酚和依托咪酯在68例无抽搐电休克治疗中的临床应用[J].福建医药杂志, 2011, 33(2): 116-117.
5. 　胡巧媚. 无抽搐电休克的麻醉体会[J]. 实用医技杂志, 2008, 15(32): 4637-4638.
6. 　Madhavan S, Nadeem Z. Response predictors in ECT: a discussion about seizure threshold[J]. BJMP, 2011, 4(2): 424.
7. 　Eranti SV, Mogg AJ, Pluck GC, et al. Methohexitone, propofol and etomidate in electroconvulsive therapy for depression: a naturalistic comparison study[J]. J Affect Disord, 2009, 113(1-2): 165-171.
8. 　Coffey CE, Lucke J, Weiner RD, et al. Seizure threshold in electroconvulsive therapy：I. Initial seizure threshold[J]. Biol Psychiatry, 1995, 37(10): 713-720.
9. 　毛洪京, 骆宏, 陈树林, 等. 导致改良电休克治疗发作不良因素分析[J]. 浙江临床医学, 2007, 9(5): 683-684.
10. 　Rasmussen K. The practice of electroconvulsive therapy: recommendations for treatment, training, and privileging[J]. J ECT, 2002, 18(1): 58-59.
11. 　Stevens A, Fischer A, Bartels M, et al. Electroconvulsive therapy: a review on indications, methods, risks and medication[J]. Eur Psychiatry, 1996, 11(4): 165-174.
12. 　Chung KF. Relationships between seizure duration and seizure threshold and stimulus dosage at electroconvulsive therapy: implications for electroconvulsive therapy practice[J]. Psychiatry Clin Neurosci, 2002, 56(5): 521-526.
13. 　van Waarde JA, van der Mast RC. Seizure thresholds in elderly patients treated with electroconvulsive therapy for major depressive disorder: a review[J]. Curr Psychiatry Rev, 2010, 6(3): 184-190.
14. 　van Waarde JA, van Oudheusden LJ, Verwey B, et al. Clinical predictors of seizure threshold in electroconvulsive therapy: a prospective study[J]. Eur Arch Psychiatry Clinc Neurosci, 2013, 263(2): 167-175.
15. 　Shapira B, Lidsky D, Gorfine, M, et a1. Electroconvulsive therapy and resistant depression:clinical implications of seizure threshold[J]. J Clin Psychiatry, 1996, 57(1): 32-38．.

West China Medical Journal

Analysis of Relative Factors Influencing Electroencephalogram Seizure Duration during Modified Electroconvulsive Therapy

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