• Department of Obstetrics, Wuhan NO. 1 Hospital, Wuhan, Hubei 430022, P. R. China;
HEYi, Email: zxghy@163.com
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Objective To probe into the clinical effects of intra-amniotic injection of ethacridine with Cook cervical ripening balloon in terminating mid-pregnancy. Methods A total of 150 mid-pregnant women who required induction of labor from January 2011 to December 2012 were randomly divided into two groups: observation group (intra-amniotic injection of ethacridine with Cook cervical ripening balloon) and control group (intra-amniotic injection of ethacridine). Results The time of labor induction was obviously shorter in the observation group than the control group [the time from using ethacridine to contraction: (29.68±4.17) vs (33.60±5.38) hours, P<0.05; total process: (7.63±2.30) vs (9.86±3.20) hours, P<0.05], and the residual rate of placental membranes [28.6% (10/35) vs 56.4%(22/39), P<0.05] was significantly lower. But there was no significant difference in postpartum hemorrhage [(81.60±17.64) vs (83.82±15.08 ) mL, P>0.05] and rate of success [100.0% (35/35) vs 94.9% (37/39), P>0.05]. Conclusion Terminating mid-pregnancy by intra-amniotic injection of ethacridine with Cook cervical ripening balloon has the advantages of shorter time and less pain, which deserves clinical application widely.

Citation: GAOXue-mei, ZHOUPing, ZHUYi-lin, HEYi. Clinical Observation of Terminating Mid-pregnancy by Intra-amniotic Injection of Ethacridine with Cook Cervical Ripening Balloon. West China Medical Journal, 2015, 30(3): 477-479. doi: 10.7507/1002-0179.20150135 Copy

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