Research on the Gender Difference in Patients with Schizophrenia in Communities_West China Medical Journal

Authors：

 YueSuping , ChenYing , HongLing , GengTing , LiHaimin , ZhangZhuoqiu , LiShuiying , ZhangShusen ,  DengHong

Mental Health Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

DengHong, Email: rhdeng88@hotmail.com

Keywords：

Schizophrenia; Gender difference; Medication compliance

DOI：

10.7507/1002-0179.201600190

Video：

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Objective To investigate the difference in first onset age, family history and medication compliance between male and female patients with schizophrenia in communities. Methods We used self-designed questionnaire to survey and analyze 372 cases of schizophrenia between June to August 2014. Results There were no significant differences between male and female schizophrenic patients in the family history, personality before the disease, education level, age, and the onset type and disease course (P > 0.05). The first onset age of male patients [(24.92±8.22) years] was significantly earlier than female patients [(27.02±11.28) years] and the difference was statistically significant (P < 0.05). The number of unmarried male patients (115, 58.97%) was significantly more than unmarried females (81, 45.76%) and the difference was statistically significant (P < 0.05). The full medication compliance rate of female patients (127, 71.75%) was significantly better than that of male patients (115, 58.97%) (P < 0.05). Conclusion The first onset age, marital status and medication compliance are significantly different between the two genders of patients with schizophrenia, which indicates that prevention, treatment and recovery measures for male and female patients should be differentiated.

Citation： YueSuping, ChenYing, HongLing, GengTing, LiHaimin, ZhangZhuoqiu, LiShuiying, ZhangShusen, DengHong. Research on the Gender Difference in Patients with Schizophrenia in Communities. West China Medical Journal, 2016, 31(4): 697-699. doi: 10.7507/1002-0179.201600190 Copy

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17.	陶然, 史杰萍, 武鸣, 等. 精神分裂症的性别差异[J]. 临床精神医学杂志, 2009, 19(1): 40-41.

1. Koychev I, El-Deredy W, Deakin JF. New visual information processing abnormality biomarker for the diagnosis of schizophrenia[J]. Expert Opin Med Diagn, 2011, 5(4): 357-368.
2. Shin JY, Martin R, Suls J. Meta-analytic evaluation of gender differences and symptom measurement strategies in acute coronary syndromes[J]. Heart Lung, 2010, 39(4): 283-295.
3. Tang YL, Gillespie CF, Epstein MP, et al. Gender differences in 542 Chinese inpatients with schizophrenia[J]. Schizophr Res, 2007, 97(1/2/3): 88-96.
4. Leung A, Chue P. Sex differences in schizophrenia, a review of the literature[J]. Acta Psychiatr Scand Suppl, 2000(401): 3-38.
5. Loranger AW. Sex difference in age at onset of schizophrenia[J]. Arch Gen Psychiatry, 1984, 41(2): 157-161.
6. Riecher-Rössler A, Häfner H. Gender aspects in schizophrenia: bridging the border between social and biological psychiatry[J]. Acta Psychiatr Scand Suppl, 2000(47): 58-62.
7. Häfner H. Gender differences in schizophrenia[J]. Psychoneuroendocrinology, 2003, 28(Suppl 2): 17–54.
8. Rao ML, Kõlsch H. Effects of estrogen on brain development and neuroprotection--implications for negative symptoms in schizophrenia[J]. Psychoneuroendocrinology, 2003, 28(Suppl 2): 83-96.
9. Crow TJ. Sex chromosomes and psychosis. The case for a pseudoautosomal locus[J]. Br J Psychiatry, 1988(153): 675-683.
10. Lalloo R, Sheiham A. Risk factors for childhood major and minor head and other injuries in a nationally representative sample[J]. Injury, 2003, 34(4): 261-266.
11. Seeman MV. Women and schizophrenia[J]. Medscape Womens Health, 2000, 5(2): 2-8.
12. Naqvi H, Khan MM, Faizi A . Gender differences in age at on set of schizophrenia[J]. Coll Physicians Surg Pak, 2005(15):345-348.
13. Lindamer LA, Bailey A, Hawthorne W, et al. Gender differences in characteristics and service use of public mental health patients with schizophrenia[J]. Psychiatr Serv, 2003, 54(10): 1407-1409.
14. 王宁, 李艳丽, 陈大春, 等. 487例住院精神分裂症患者临床特征的性别差异[J]. 中国民康医学, 2010, 22(17): 2221-2223.
15. 林建荣, 陈国中, 关炳波, 等. 影响精神分裂症患者治疗依从性的相关因素研究[J]. 中国神经精神疾病杂志, 2000, 26(3): 152-155.
16. Gilmer TP, Dolder CR, Lacro JP, et al. Adherence to treatment with antipsychotic medication and health care costs among Medicaid beneficiaries with schizophrenia[J]. Am J Psychiatry, 2004, 161(4): 692-699.
17. 陶然, 史杰萍, 武鸣, 等. 精神分裂症的性别差异[J]. 临床精神医学杂志, 2009, 19(1): 40-41.

West China Medical Journal

Research on the Gender Difference in Patients with Schizophrenia in Communities

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