• Department of General Thoracic Surgery, Medical College of Yangzhou University, Yangzhou Jiangsu, 225001, P.R.China. Corresponding author: SHI Hongcan, E-mail: shihongcan@hotmail.com;
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Objective To summarize the recent research situation and progress of decellularized matrix in tissue engineered trachea transplantation and to forecast the possible perspects. Methods Recent original articles about study and application for decellularized matrix in tissue engineered trachea were reviewed. The application and study of different decellularized matrices involved in animals or patients with tracheal lesions were elaborated. Results Decellularized matrices researched and applied in tissue engineered trachea include jejunum, urinary bladder, aorta, and trachea. Conclusion Decellularized urinary bladder matrix and jejunal matrix appears to be efficacious method for the patch repair of partial circumferential tracheal defects. The application of decellularized aortic matrix may need more study, and decellularized tracheal matrix has a bright future in long tracheal defects.

Citation: ZHANG Fangbiao,ZHANG Weidong,SHI Hongcan.. RESEARCH PROGRESS OF DECELLULARIZED MATRIX IN TISSUE ENGINEERED TRACHEA TRANSPLANTATION. Chinese Journal of Reparative and Reconstructive Surgery, 2013, 27(2): 223-226. doi: 10.7507/1002-1892.20130048 Copy

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