RESEARCH PROGRESS OF THREE-DIMENSIONAL PRINTING POROUS SCAFFOLDS FOR BONE TISSUE ENGINEERING_Chinese Journal of Reparative and Reconstructive Surgery

Authors：

WUTianqi ^1,2 ,  YANGChunxi ¹

1. Department of Orthopedics, Shanghai Tenth People's Hospital, Tenth People's Hospital of Tongji University, Shanghai, 200072, P. R. China;
2. Tongji University School of Medicine;

Corresponding author：

YANGChunxi, Email: chunxi_yang@163.com

Keywords：

Three-dimensional printing; Porous scaffold; Bone repairing; Scaffold material; Bioprinting

DOI：

10.7507/1002-1892.20160101

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To summarize the research progress of several three-dimensional (3-D) printing scaffold materials in bone tissue engineering. Method The recent domestic and international articles about 3-D printing scaffold materials were reviewed and summarized. Results Compared with conventional manufacturing methods, 3-D printing has distinctive advantages, such as enhancing the controllability of the structure and increasing the productivity. In addition to the traditional metal and ceramic scaffolds, 3-D printing scaffolds carrying seeding cells and tissue factors as well as scaffolds filling particular drugs for special need have been paid more and more attention. Conclusions The development of 3-D printing porous scaffolds have revealed new perspectives in bone repairing. But it is still at the initial stage, more basic and clinical researches are still needed.

Citation： WUTianqi, YANGChunxi. RESEARCH PROGRESS OF THREE-DIMENSIONAL PRINTING POROUS SCAFFOLDS FOR BONE TISSUE ENGINEERING. Chinese Journal of Reparative and Reconstructive Surgery, 2016, 30(4): 509-513. doi: 10.7507/1002-1892.20160101 Copy

1.	贺超良, 汤朝晖, 田华雨, 等. 3D打印技术制备生物医用高分子材料的研究进展. 高分子学报, 2013, (6) :722-732.
2.	Butscher A, Bohner M, Hofmann S, et al. Structural and material approaches to bone tissue engineering in powder-based three-dimensional printing. Acta Biomaterialia, 2011, 7(3) :907-920.
3.	胡堃, 刘斌. 骨移植材料发展趋势. 生物骨科材料与临床研究, 2010, 7(3) :32-38.
4.	Luangphakdy V, Walker E, Shinohara K, et al. Evaluation of osteoconductive scaffolds in the canine femoral multi-defect model. Tissue Eng Part A, 2013, 19(5-6) :634-648.
5.	郑扬, 李危石, 刘忠军. 骨组织3D打印:骨再生的未来. 北京大学学报(医学版), 2015, 47(2) :203-206.
6.	El-Hajje A, Kolos EC, Wang JK, et al. Physical and mechanical characterisation of 3D-printed porous titanium for biomedical applications. J Mater Sci Mater Med, 2014, 25(11) :2471-2480.
7.	Zhang S, Cheng X, Yao Y, et al. Porous niobium coatings fabricated with selective laser melting on titanium substrates:Preparation, characterization, and cell behavior. Mater Sci Eng C Mater Biol Appl, 2015, 53:50-59.
8.	Klein GT, Lu T, Wang MY. 3D printing and neurosurgery-ready for prime time. World Neurosurg, 2013, 80(3-4) :233-235.
9.	袁景, 甄平, 赵红斌. 高性能多孔β-磷酸三钙骨组织工程支架的3D打印. 中国组织工程研究, 2014, 18(43) :6914-6921.
10.	Zhang Y, Xia L, Zhai D, et al. Mesoporous bioactive glass nanolayer-functionalized 3D-printed scaffolds for accelerating osteogenesis and angiogenesis. Nanoscale, 2015, 7(45) :19207-19221.
11.	Lee KW, Wang S, Lu L, et al. Fabrication and characterization of poly (propylene fumarate) scaffolds with controlled pore structures using 3-dimensional printing and injection molding. Tissue Eng, 2006, 12(10) :2801-2811.
12.	Stocco E, Barbon S, Grandi F, et al. Partially oxidized polyvinyl alcohol as a promising material for tissue engineering. J Tissue Eng Regen Med, 2015.[Epub ahead of print].
13.	Rahmati S, Shirazi F, Baghayeri H. Perusing piezoelectric head performance in a new 3-D printing design. Tsinghua Science & Technology, 2009, 14(S1) :24-28.
14.	Zhou Z, Buchanan F, Mitchell C, et al. Printability of calcium phosphate:Calcium sulfate powders for the application of tissue engineered bone scaffolds using the 3D printing technique. Mater Sci Eng C Mater Biol Appl, 2014, 38:1-10.
15.	Inzana JA, Olvera D, Fuller SM, et al. 3D printing of composite calcium phosphate and collagen scaffolds for bone regeneration. Biomaterials, 2014, 35(13) :4026-4034.
16.	Pors Nielsen S. The biological role of strontium. Bone, 2004, 35(3) :583-588.
17.	Tarafder S, Davies NM, Bandyopadhyay A, et al. 3D printed tricalcium phosphate bone tissue engineering scaffolds:Effect of SrO and MgO doping on in vivo osteogenesis in a rat distal femoral defect model. Biomater Sci, 2013, 1(12) :1250-1259.
18.	Jiankang H, Dichen L, Bingheng L, et al. Custom fabrication of composite tibial hemi-knee joint combining CAD/CAE/CAM techniques. Proc Inst Mech Eng H, 2006, 220(8) :823-830.
19.	Kao CT, Lin CC, Chen YW, et al. Poly (dopamine) coating of 3D printed poly (lactic acid) scaffolds for bone tissue engineering. Mater Sci Eng C Mater Biol Appl, 2015, 56:165-173.
20.	倪硕, 李澎, 张卫国, 等. 制备软骨组织工程支架的方法. 中国组织工程研究, 2014, 18(3) :446-451.
21.	李奎锋, 郭立坤, 樊渝江, 等. 胶原水凝胶支架用于软骨组织工程的实验研究. 中国修复重建外科杂志, 2012, 26(11) :1356-1361.
22.	Zhu M, Li K, Zhu Y, et al. 3D-printed hierarchical scaffold for localized isoniazid/rifampin drug delivery and osteoarticular tuberculosis therapy. Acta Biomater, 2015, 16:145-155.
23.	朱辉. 数字化载银珊瑚羟基磷灰石人工骨的制备及生物学研究. 广州:南方医科大学, 2012.
24.	Selimis A, Mironov V, Farsari M. Direct laser writing:Principles and materials for scaffold 3D printing. Microelectronic Engineering, 2015, 132:83-89.

1. 贺超良, 汤朝晖, 田华雨, 等. 3D打印技术制备生物医用高分子材料的研究进展. 高分子学报, 2013, (6) :722-732.
2. Butscher A, Bohner M, Hofmann S, et al. Structural and material approaches to bone tissue engineering in powder-based three-dimensional printing. Acta Biomaterialia, 2011, 7(3) :907-920.
3. 胡堃, 刘斌. 骨移植材料发展趋势. 生物骨科材料与临床研究, 2010, 7(3) :32-38.
4. Luangphakdy V, Walker E, Shinohara K, et al. Evaluation of osteoconductive scaffolds in the canine femoral multi-defect model. Tissue Eng Part A, 2013, 19(5-6) :634-648.
5. 郑扬, 李危石, 刘忠军. 骨组织3D打印:骨再生的未来. 北京大学学报(医学版), 2015, 47(2) :203-206.
6. El-Hajje A, Kolos EC, Wang JK, et al. Physical and mechanical characterisation of 3D-printed porous titanium for biomedical applications. J Mater Sci Mater Med, 2014, 25(11) :2471-2480.
7. Zhang S, Cheng X, Yao Y, et al. Porous niobium coatings fabricated with selective laser melting on titanium substrates:Preparation, characterization, and cell behavior. Mater Sci Eng C Mater Biol Appl, 2015, 53:50-59.
8. Klein GT, Lu T, Wang MY. 3D printing and neurosurgery-ready for prime time. World Neurosurg, 2013, 80(3-4) :233-235.
9. 袁景, 甄平, 赵红斌. 高性能多孔β-磷酸三钙骨组织工程支架的3D打印. 中国组织工程研究, 2014, 18(43) :6914-6921.
10. Zhang Y, Xia L, Zhai D, et al. Mesoporous bioactive glass nanolayer-functionalized 3D-printed scaffolds for accelerating osteogenesis and angiogenesis. Nanoscale, 2015, 7(45) :19207-19221.
11. Lee KW, Wang S, Lu L, et al. Fabrication and characterization of poly (propylene fumarate) scaffolds with controlled pore structures using 3-dimensional printing and injection molding. Tissue Eng, 2006, 12(10) :2801-2811.
12. Stocco E, Barbon S, Grandi F, et al. Partially oxidized polyvinyl alcohol as a promising material for tissue engineering. J Tissue Eng Regen Med, 2015.[Epub ahead of print].
13. Rahmati S, Shirazi F, Baghayeri H. Perusing piezoelectric head performance in a new 3-D printing design. Tsinghua Science & Technology, 2009, 14(S1) :24-28.
14. Zhou Z, Buchanan F, Mitchell C, et al. Printability of calcium phosphate:Calcium sulfate powders for the application of tissue engineered bone scaffolds using the 3D printing technique. Mater Sci Eng C Mater Biol Appl, 2014, 38:1-10.
15. Inzana JA, Olvera D, Fuller SM, et al. 3D printing of composite calcium phosphate and collagen scaffolds for bone regeneration. Biomaterials, 2014, 35(13) :4026-4034.
16. Pors Nielsen S. The biological role of strontium. Bone, 2004, 35(3) :583-588.
17. Tarafder S, Davies NM, Bandyopadhyay A, et al. 3D printed tricalcium phosphate bone tissue engineering scaffolds:Effect of SrO and MgO doping on in vivo osteogenesis in a rat distal femoral defect model. Biomater Sci, 2013, 1(12) :1250-1259.
18. Jiankang H, Dichen L, Bingheng L, et al. Custom fabrication of composite tibial hemi-knee joint combining CAD/CAE/CAM techniques. Proc Inst Mech Eng H, 2006, 220(8) :823-830.
19. Kao CT, Lin CC, Chen YW, et al. Poly (dopamine) coating of 3D printed poly (lactic acid) scaffolds for bone tissue engineering. Mater Sci Eng C Mater Biol Appl, 2015, 56:165-173.
20. 倪硕, 李澎, 张卫国, 等. 制备软骨组织工程支架的方法. 中国组织工程研究, 2014, 18(3) :446-451.
21. 李奎锋, 郭立坤, 樊渝江, 等. 胶原水凝胶支架用于软骨组织工程的实验研究. 中国修复重建外科杂志, 2012, 26(11) :1356-1361.
22. Zhu M, Li K, Zhu Y, et al. 3D-printed hierarchical scaffold for localized isoniazid/rifampin drug delivery and osteoarticular tuberculosis therapy. Acta Biomater, 2015, 16:145-155.
23. 朱辉. 数字化载银珊瑚羟基磷灰石人工骨的制备及生物学研究. 广州:南方医科大学, 2012.
24. Selimis A, Mironov V, Farsari M. Direct laser writing:Principles and materials for scaffold 3D printing. Microelectronic Engineering, 2015, 132:83-89.

Previous Article
DEVELOPMENT OF HYPOXIA-INDUCIBLE FACTOR 1α IN TISSUE ENGINEERED ANGIOGENESIS AND OSTEOGENESIS
Next Article
APPLICATION STRATEGY OF ANKLE AND HINDFOOT ARTHRODESIS

Chinese Journal of Reparative and Reconstructive Surgery

RESEARCH PROGRESS OF THREE-DIMENSIONAL PRINTING POROUS SCAFFOLDS FOR BONE TISSUE ENGINEERING

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content