1. |
Sampara P, Banala RR, Vemuri SK, et al. Understanding the molecular biology of intervertebral disc degeneration and potential gene therapy strategies for regeneration: a review. Gene Ther, 2018, 25(2): 67-82.
|
2. |
Kadow T, Sowa G, Vo N, et al. Molecular basis of intervertebral disc degeneration and herniations: what are the important translational questions? Clin Orthop Relat Res, 2015, 473(6): 1903-1912.
|
3. |
侯孝忠, 徐林飞, 易威威, 等. 内质网应激对吸烟诱导的髓核细胞凋亡与炎性反应的影响研究. 中国修复重建外科杂志, 2019, 33(6): 736-742.
|
4. |
陈琪, 石芳芳, 杨曦, 等. 不同代次髓核细胞生物学特性的比较研究. 中国修复重建外科杂志, 2018, 32(6): 660-667.
|
5. |
MacDonald IJ, Liu SC, Huang CC, et al. Associations between adipokines in arthritic disease and implications for obesity. Int J Mol Sci, 2019, 20(6): pii: E1505.
|
6. |
Ruiz-Fernández C, Francisco V, Pino J, et al. Molecular relationships among obesity, inflammation and intervertebral disc degeneration: are adipokines the common link? Int J Mol Sci, 2019, 20(8): pii: E2030.
|
7. |
Fasshauer M, Blüher M. Adipokines in health and disease. Trends Pharmacol Sci, 2015, 36(7): 461-470.
|
8. |
Gandhi R, Sharma A, Kapoor M, et al. Racial differences in serum adipokine and insulin levels in a matched osteoarthritis sample: a pilot study. J Obes, 2016, 2016: 8746268.
|
9. |
Ouchi N, Parker JL, Lugus JJ, et al. Adipokines in inflammation and metabolic disease. Nat Rev Immunol, 2011, 11(2): 85-97.
|
10. |
Dowdell J, Erwin M, Choma T, et al. Intervertebral disk degeneration and repair. Neurosurgery, 2017, 80(3S): S46-S54.
|
11. |
Segar AH, Fairbank JCT, Urban J. Leptin and the intervertebral disc: a biochemical link exists between obesity, intervertebral disc degeneration and low back pain-an in vitro study in a bovine model. Eur Spine J, 2019, 28(2): 214-223.
|
12. |
Francisco V, Pino J, Campos-Cabaleiro V, et al. Obesity, fat mass and immune system: role for leptin. Front Physiol, 2018, 9: 640.
|
13. |
Zhao CQ, Liu D, Li H, et al. Expression of leptin and its functional receptor on disc cells: contribution to cell proliferation. Spine (Phila Pa 1976), 2008, 33(23): E858-E864.
|
14. |
Li Z, Shen J, Wu WK, et al. Leptin induces cyclin D1 expression and proliferation of human nucleus pulposus cells via JAK/STAT, PI3K/Akt and MEK/ERK pathways. PLoS One, 2012, 7(12): e53176.
|
15. |
Li Z, Yu X, Liang J, et al. Leptin downregulates aggrecan through the p38-ADAMST pathway in human nucleus pulposus cells. PLoS One, 2014, 9(10): e109595.
|
16. |
Han YC, Ma B, Guo S, et al. Leptin regulates disc cartilage endplate degeneration and ossification through activation of the MAPK-ERK signalling pathway in vivo and in vitro. J Cell Mol Med, 2018, 22(4): 2098-2109.
|
17. |
Liu M, Liu F. Regulation of adiponectin multimerization, signaling and function. Best Pract Res Clin Endocrinol Metab, 2014, 28(1): 25-31.
|
18. |
Yamauchi T, Iwabu M, Okada-Iwabu M, et al. Adiponectin receptors: a review of their structure, function and how they work. Best Pract Res Clin Endocrinol Metab, 2014, 28(1): 15-23.
|
19. |
Yuan B, Huang L, Yan M, et al. Adiponectin downregulates TNF-α expression in degenerated intervertebral discs. Spine (Phila Pa 1976), 2018, 43(7): E381-E389.
|
20. |
Terashima Y, Kakutani K, Yurube T, et al. Expression of adiponectin receptors in human and rat intervertebral disc cells and changes in receptor expression during disc degeneration using a rat tail temporary static compression model. J Orthop Surg Res, 2016, 11(1): 147.
|
21. |
Jamaluddin MS, Weakley SM, Yao Q, et al. Resistin: functional roles and therapeutic considerations for cardiovascular disease. Br J Pharmacol, 2012, 165(3): 622-632.
|
22. |
Fang WQ, Zhang Q, Peng YB, et al. Resistin level is positively correlated with thrombotic complications in Southern Chinese metabolic syndrome patients. J Endocrinol Invest, 2011, 34(2): e36-e42.
|
23. |
Li Z, Wang X, Pan H, et al. Resistin promotes CCL4 expression through toll-like receptor-4 and activation of the p38-MAPK and NF-κB signaling pathways: implications for intervertebral disc degeneration. Osteoarthritis Cartilage, 2017, 25(2): 341-350.
|
24. |
Liu C, Yang H, Gao F, et al. Resistin Promotes Intervertebral Disc Degeneration by Upregulation of ADAMTS-5 Through p38 MAPK Signaling Pathway. Spine (Phila Pa 1976), 2016, 41(18): 1414-1420.
|
25. |
Wei J, Hettinghouse A, Liu C. The role of progranulin in arthritis. Ann N Y Acad Sci, 2016, 1383(1): 5-20.
|
26. |
Zhao YP, Tian QY, Liu B, et al. Progranulin knockout accelerates intervertebral disc degeneration in aging mice. Sci Rep, 2015, 5: 9102.
|
27. |
Wang S, Wei J, Fan Y, et al. Progranulin is positively associated with intervertebral disc degeneration by interaction with IL-10 and IL-17 through TNF pathways. Inflammation, 2018, 41(5): 1852-1863.
|
28. |
Francisco V, Pérez T, Pino J, et al. Biomechanics, obesity, and osteoarthritis. The role of adipokines: When the levee breaks. J Orthop Res, 2018, 36(2): 594-604.
|
29. |
Radzicka S, Pietryga M, Iciek R, et al. The role of visfatin in pathogenesis of gestational diabetes (GDM). Ginekol Pol, 2018, 89(9): 518-521.
|
30. |
Shi C, Wu H, Du D, et al. Nicotinamide phosphoribosyltransferase inhibitor APO866 prevents IL-1β-induced human nucleus pulposus cell degeneration via autophagy. Cell Physiol Biochem, 2018, 49(6): 2463-2482.
|
31. |
Colldén G, Tschöp MH, Müller TD. Therapeutic potential of targeting the ghrelin pathway. Int J Mol Sci, 2017, 18(4): pii: E798.
|
32. |
Pereira JADS, da Silva FC, de Moraes-Vieira PMM. The impact of ghrelin in metabolic diseases: an immune perspective. J Diabetes Res, 2017, 2017: 4527980.
|
33. |
Li W, Wu X, Qu R, et al. Ghrelin protects against nucleus pulposus degeneration through inhibition of NF-κB signaling pathway and activation of Akt signaling pathway. Oncotarget, 2017, 8(54): 91887-91901.
|
34. |
Francisco V, Pino J, Gonzalez-Gay MA, et al. Adipokines and inflammation: is it a question of weight? Br J Pharmacol, 2018, 175(10): 1569-1579.
|
35. |
Kao TH, Peng YJ, Salter DM, et al. Nerve growth factor increases MMP9 activity in annulus fibrosus cells by upregulating lipocalin 2 expression. Eur Spine J, 2015, 24(9): 1959-1968.
|
36. |
Kao TH, Peng YJ, Tsou HK, et al. Nerve growth factor promotes expression of novel genes in intervertebral disc cells that regulate tissue degradation: Laboratory investigation. J Neurosurg Spine, 2014, 21(4): 653-661.
|
37. |
Paesold G, Nerlich AG, Boos N. Biological treatment strategies for disc degeneration: potentials and shortcomings. Eur Spine J, 2007, 16(4): 447-468.
|
38. |
Cha YJ, Koo JS. Adipokines as therapeutic targets in breast cancer treatment. Expert Opin Ther Targets, 2018, 22(11): 941-953.
|
39. |
Chung HS, Choi KM. Adipokines and myokines: a pivotal role in metabolic and cardiovascular disorders. Curr Med Chem, 2018, 25(20): 2401-2415.
|
40. |
Pramanik S, Rathwa N, Patel R, et al. Treatment avenues for type 2 diabetes and current perspectives on adipokines. Curr Diabetes Rev, 2018, 14(3): 201-221.
|
41. |
Francisco V, Ruiz-Fernández C, Pino J, et al. Adipokines: Linking metabolic syndrome, the immune system, and arthritic diseases. Biochem Pharmacol, 2019, 165: 196-206.
|