Pattern of lymph node metastasis in 177 thoracic esophageal cancer patients_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

DAILei , RENZixue , ZHANGAnqing ,  ZHANGRongxin

Department of Thoracic Surgery, West Branch of Anhui Provincial Hospital, Anhui Provincial Tumour Hospital, Hefei, 230088, P.R.China;

Corresponding author：

ZHANGRongxin, Email: zrx13855219010@126.com

Keywords：

Esophageal tumor; lymphatic metastasis; surgical procedures, operative; lymph node dissection

DOI：

10.7507/1007-4848.201606002

Video：

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Objective This study analyzed the pattern and influence factors of lymph node metastasis in thoracic esophageal cancer to provide a reference for the lymph node dissection for esophageal cancer. Methods Clinical data of 177 patients with thoracic esophageal cancer receiving the lymph node dissection in our department from 2015 to 2016 were retrospectively analyzed. There were 125 males and 52 females with a median age of 64 years, ranging from 18 to 86 years. We excluded cervical esophageal cancer and adenocarcinoma of the esophagogastric junction and analyzed the relationship between lymph node metastasis and tumor pathological type, depth of invasion, degree of differentiation and length. Results Of the 177 patients, 76 (42.9%) were found to have lymph node metastasis. In the 4 977 dissected lymph nodes, metastasis was identfied in 361 (7.3%) lymph nodes. The rate of lymph node metastasis in thoracic esophageal carcinoma was not related to the location and length of the tumor (P>0.05), but related to the depth of invasion and the degree of differentiation (P<0.05). Conclusion Lymph node metastasis is prone to present in the early stage of thoracic esophageal cancer. According to the characteristics of lymph node metastasis in thoracic esophageal carcinoma, we need have a standardized, systematic and focused lymph node dissection.

Citation： DAILei, RENZixue, ZHANGAnqing, ZHANGRongxin. Pattern of lymph node metastasis in 177 thoracic esophageal cancer patients. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2017, 24(2): 122-126. doi: 10.7507/1007-4848.201606002 Copy

1.	赵海龙, 薛继军, 郑凤长, 等. 食管癌术后生存五年以上患者复发转移的相关因素分析. 中国胸心血管外科临床杂志, 2016, 23(6): 546-549.
2.	Takubo K, Makuuchi H, Fujita H, et al. Japanese classification of esophageal cancer, tenth edition: part Ⅰ. Esophagus, 2009, 6(1): 1-25.
3.	Lee HJ, Lee H, Park JC, et al. Treatment strategy after endoscopic resection of superficial esophageal squamous cell carcinoma: A single institution experience. Gut Liver, 2015, 9(6): 714-719.
4.	Park JS, Youn YH, Park JJ, et al. Clinical outcomes of endoscopic submucosal dissection for superficial esophageal squamous neoplasms. Clin Endosc, 2016, 49(2): 168-175.
5.	杨军, 陈诗娴, 吕必宏, 等. 胸段食管癌淋巴结转移特征及对预后的影响. 江苏医药, 2016, 42(13): 1474-1477.
6.	秦建军, 李印. 日本 2015 食管癌诊治指南解读: 胸段食管癌的外科治疗. 中国胸心血管外科临床杂志, 2016, 23(2): 101-103.
7.	Liebermann-Meffert D. Anatomical basis for the approach and extent of surgical treatment of esophageal cancer. Dis Esophagus, 2001, 14(2): 81-84.
8.	王军, 韩春, 祝淑钗, 等. 胸段食管癌淋巴结转移规律及其影响因素. 中国肿瘤临床, 2010, 37(2): 90-93.
9.	Tachimori Y, Ozawa S, Numasaki H, et al. Efficacy of lymph node dissection by node zones according to tumor location for esophageal squamous cell carcinoma. Esophagus, 2016, 13: 1-7.
10.	崔岳, 谢天鹏, 杨晓军, 等. 胸段食管癌上纵隔淋巴结转移规律的临床分析. 中国胸心血管外科临床杂志, 2015, 22(11): 1026-1030.
11.	中国抗癌协会食管癌专业委员会. 食管癌规范化诊治指南. 北京: 中国协和医科大学出版社, 2011. 24-61.
12.	陈跃军, 邹求益, 朱广, 等. 胸段食管癌淋巴结转移特点的临床研究. 中华胃肠外科杂志, 2013, 16(9): 835-837.
13.	Lin J, Kang M, Chen S, et al. Feasibility and strategy for left tracheobronchial lymph node dissection in thoracolaparoscopic esophageal cancer surgery. Thorac Cancer, 2016, 7(2): 199-206.
14.	Ye T, Sun Y, Zhang Y, et al. Three-field or two-field resection for thoracic esophageal cancer: a meta-analysis. Ann Thorac Surg, 2013, 96(6): 1933-1941.
15.	Ma GW, Situ DR, Ma QL, et al. Three-field vs two-field lymph node dissection for esophageal cancer: a meta-analysis. World J Gastroenterol, 2014, 20(47): 18022-18030.
16.	张颖颖, 王玉, 张航, 等. 三野与二野淋巴结清扫术治疗食管癌疗效及安全性的系统评价与 Meta 分析. 中国胸心血管外科临床杂志, 2016, 23(8): 814-821.
17.	任自学, 张荣新, 王圣应, 等. 选择性三野淋巴结清扫在胸中、上段食管癌中的应用. 临床医学与护理研究, 2014, 13(3): 40-41.
18.	柳常青, 解明然, 郭明发, 等. 微创 Ivor-Lewis 食管癌根治术围手术期结果分析. 中华肿瘤防治杂志, 2014, 21(6): 454-457.
19.	陶开义, 陈奇勋, 赵强, 等. 胸腹腔镜与传统 Ivor-Lewis 手术对早中期食管癌患者术后生活质量的影响. 中国肿瘤, 2016, 25(3): 226-232.
20.	Bencini L, Moraldi L, Bartolini I, et al. Esophageal surgery in minimally invasive era. World J Gastrointest Surg, 2016, 8(1): 52-64.

1. 赵海龙, 薛继军, 郑凤长, 等. 食管癌术后生存五年以上患者复发转移的相关因素分析. 中国胸心血管外科临床杂志, 2016, 23(6): 546-549.
2. Takubo K, Makuuchi H, Fujita H, et al. Japanese classification of esophageal cancer, tenth edition: part Ⅰ. Esophagus, 2009, 6(1): 1-25.
3. Lee HJ, Lee H, Park JC, et al. Treatment strategy after endoscopic resection of superficial esophageal squamous cell carcinoma: A single institution experience. Gut Liver, 2015, 9(6): 714-719.
4. Park JS, Youn YH, Park JJ, et al. Clinical outcomes of endoscopic submucosal dissection for superficial esophageal squamous neoplasms. Clin Endosc, 2016, 49(2): 168-175.
5. 杨军, 陈诗娴, 吕必宏, 等. 胸段食管癌淋巴结转移特征及对预后的影响. 江苏医药, 2016, 42(13): 1474-1477.
6. 秦建军, 李印. 日本 2015 食管癌诊治指南解读: 胸段食管癌的外科治疗. 中国胸心血管外科临床杂志, 2016, 23(2): 101-103.
7. Liebermann-Meffert D. Anatomical basis for the approach and extent of surgical treatment of esophageal cancer. Dis Esophagus, 2001, 14(2): 81-84.
8. 王军, 韩春, 祝淑钗, 等. 胸段食管癌淋巴结转移规律及其影响因素. 中国肿瘤临床, 2010, 37(2): 90-93.
9. Tachimori Y, Ozawa S, Numasaki H, et al. Efficacy of lymph node dissection by node zones according to tumor location for esophageal squamous cell carcinoma. Esophagus, 2016, 13: 1-7.
10. 崔岳, 谢天鹏, 杨晓军, 等. 胸段食管癌上纵隔淋巴结转移规律的临床分析. 中国胸心血管外科临床杂志, 2015, 22(11): 1026-1030.
11. 中国抗癌协会食管癌专业委员会. 食管癌规范化诊治指南. 北京: 中国协和医科大学出版社, 2011. 24-61.
12. 陈跃军, 邹求益, 朱广, 等. 胸段食管癌淋巴结转移特点的临床研究. 中华胃肠外科杂志, 2013, 16(9): 835-837.
13. Lin J, Kang M, Chen S, et al. Feasibility and strategy for left tracheobronchial lymph node dissection in thoracolaparoscopic esophageal cancer surgery. Thorac Cancer, 2016, 7(2): 199-206.
14. Ye T, Sun Y, Zhang Y, et al. Three-field or two-field resection for thoracic esophageal cancer: a meta-analysis. Ann Thorac Surg, 2013, 96(6): 1933-1941.
15. Ma GW, Situ DR, Ma QL, et al. Three-field vs two-field lymph node dissection for esophageal cancer: a meta-analysis. World J Gastroenterol, 2014, 20(47): 18022-18030.
16. 张颖颖, 王玉, 张航, 等. 三野与二野淋巴结清扫术治疗食管癌疗效及安全性的系统评价与 Meta 分析. 中国胸心血管外科临床杂志, 2016, 23(8): 814-821.
17. 任自学, 张荣新, 王圣应, 等. 选择性三野淋巴结清扫在胸中、上段食管癌中的应用. 临床医学与护理研究, 2014, 13(3): 40-41.
18. 柳常青, 解明然, 郭明发, 等. 微创 Ivor-Lewis 食管癌根治术围手术期结果分析. 中华肿瘤防治杂志, 2014, 21(6): 454-457.
19. 陶开义, 陈奇勋, 赵强, 等. 胸腹腔镜与传统 Ivor-Lewis 手术对早中期食管癌患者术后生活质量的影响. 中国肿瘤, 2016, 25(3): 226-232.
20. Bencini L, Moraldi L, Bartolini I, et al. Esophageal surgery in minimally invasive era. World J Gastrointest Surg, 2016, 8(1): 52-64.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Pattern of lymph node metastasis in 177 thoracic esophageal cancer patients

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