Influencing factors of postoperative cough after lung resection in patients with lung cancer by video-assisted thoracic surgery: a single centre prospective study_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

LIN Rongjia ,  CHE Guowei , XU Zhihua , WANG Mingming , LI Pengfei , YANG Mei

Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China;

Corresponding author：

CHE Guowei, Email: guowei_che@yahoo.com

Keywords：

Influencing factor; pulmonary thoracoscope surgery; cough; lung cancer

DOI：

10.7507/1007-4848.201704008

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To explore the factors of postoperative cough in lung cancer patients. Methods Totally 130 lung cancer patients of single medical team (average age of 58.75±9.34 years, 65 males and 65 females), from February 2016 to February 2017 in the Department of Thoracic Surgery of West China Hospital of Sichuan University, were investigated by Mandarin Chinese version of the Leicester Cough Questionnaire (LCQ-MC). We analyzed and calculated the preoperative and postoperative scores of LCQ-MC, Cronbach α and the influencing factor. Results The preoperative score of LCQ-MC's physiological dimension was significantly lower in the postoperative cough group (6.30±0.76) than that of the postoperative non-cough group (6.56±0.60,P=0.044), while the preoperative total score of LCQ-MC (19.53±1.78, 20.03±1.45) was not statistically different (P=0.080). The postoperative score of LCQ-MC was significantly lower in the postoperative cough group (17.32±2.79) than that of the postoperative non-cough group (19.70±1.39,P<0.001). And the scores of physiological, psychological and social dimension were significantly lower in the postoperative cough group (5.32 ±1.14, 5.73±1.14, 6.23±0.89) than those of the postoperative non-cough group (6.25±0.63, 6.67±0.54, 6.78±0.49) (P values were all less than 0.001). The result of multi-factor logistic regression analysis showed the condition of preoperative cough symptom (OR=0.354, 95%CI=0.126–0.994, P=0.049) and anesthesia time (OR=1.021, 95% CI=1.003–1.040, P=0.021) were the risk factors. Conclusion The risk factors of postoperative cough symptoms in lung cancer patients are the condition of preoperative cough symptoms and anesthesia time.

Citation： LIN Rongjia, CHE Guowei, XU Zhihua, WANG Mingming, LI Pengfei, YANG Mei. Influencing factors of postoperative cough after lung resection in patients with lung cancer by video-assisted thoracic surgery: a single centre prospective study. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2017, 24(10): 748-752. doi: 10.7507/1007-4848.201704008 Copy

1.	Lee KK, Matos S, Evans DH, et al. A longitudinal assessment of acute cough. Am J Respir Crit Care Med, 2013, 187(9): 991-997.
2.	Urso B, Michaels S. Differentiation of lung cancer, empyema, and abscess through the investigation of a dry cough. Cureus, 2016, 8(11): e896.
3.	Driessen AK, McGovern AE, Narula M, et al. Central mechanisms of airway sensation and cough hypersensitivity. Pulm Pharmacol Ther, 2017, S1094-5539(17)30016-0.
4.	Molassiotis A, Smith JA, Mazzone P, et al. Symptomatic treatment of cough among adult patients with lung cancer: chest guidelines and expert panel report. Chest, 2017, 151(4):861-874.
5.	车国卫, 刘伦旭, 石应康. 加速康复外科临床应用现状与思考. 中国胸心血管外科临床杂志, 2016, 23(3): 211-215.0.
6.	车国卫, 李为民, 刘伦旭. 快速肺康复需要围手术期流程优化. 中国胸心血管外科临床杂志, 2016, 23(3): 216-220.0.
7.	Liu L, Che G, Pu Q, et al. A new concept of endoscopic lung cancer resection: Single-direction thoracoscopic lobectomy. Surg Oncol, 2010, 19(2): e71-e77.
8.	Zhi XY, Yu JM, Shi YK. Chinese guidelines on the diagnosis and treatment of primary lung cancer(2015 version). Cancer, 2015, 121(Suppl 17): 3165-3181.
9.	杨梅, 樊骏 ,周红霞, 等. 胸腔镜肺癌肺叶切除术后 16F 较 28F 胸腔引流管应用的临床优势. 中国肺癌杂志, 2015, 18(8): 512-517.0.
10.	Gao YH, Guan WJ, Xu G, et al. Validation of the Mandarin Chinese version of the Leicester Cough Questionnaire in bronchiectasis. Int J Tuberc Lung Dis, 2014, 18(12): 1431-1437.
11.	Raj AA, Pavord DI, Birring SS. Clinical cough IV:what is the minimal important difference for the Leicester Cough Questionnaire? Handb Exp Pharmacol, 2009, 187: 311-320.
12.	Yousaf N, Lee KK, Jayaraman B, et al. The assessment of quality of life in acute cough with the Leicester Cough Questionnaire (LCQ-acute). Cough, 2011, 7(1): 4.
13.	Molassiotis A, Smith JA, Bennett MI, et al. Clinical expert guidelines for the management of cough in lung cancer: report of a UK task group on cough. Cough, 2010, 6: 9. doi: 10.1186/1745-9974-6-9.
14.	Harle AS, Blackhall FH, Smith JA, et al. Understanding cough and its management in lung cancer. Curr Opin Support Palliat Care, 2012, 6(2): 153-162.
15.	Lee SY, Yoo JY, Kim JY, et al. Optimal effect-site concentration of remifentanil for preventing cough during removal of the double-lumen endotracheal tube from sevoflurane-remifentanil anesthesia: A prospective clinical trial. Medicine (Baltimore), 2016, 95(24): e3878.
16.	Birring SS, Spinou A. How best to measure cough clinically. Curr Opin Pharmacol, 2015, 22: 37-40.
17.	Wang K, Birring SS, Taylor K, et al. Montelukast for postinfectious cough in adults: a double-blind randomised placebo-controlled trial. Lancet Respir Med, 2014, 2(1): 35-43.
18.	黄佳, 罗清泉, 申屠阳,等. 右肺癌系统性清扫淋巴结术后顽固性咳嗽防治方法的探讨. 中国肺癌杂志, 2010, 13(10): 975-979.0.
19.	宋志芳, 韩兆杰, 林琳, 等. SF-36 量表评价胸外科住院患者生活质量的信度和效度. 中国胸心血管外科临床杂志, 2014, 21(2):164-167.0.
20.	李斌恺, 赖克方, 王法霞, 等. 慢性咳嗽患者的生活质量调查. 国际呼吸杂志, 2011, 31(5): 326-329.0.

1. Lee KK, Matos S, Evans DH, et al. A longitudinal assessment of acute cough. Am J Respir Crit Care Med, 2013, 187(9): 991-997.
2. Urso B, Michaels S. Differentiation of lung cancer, empyema, and abscess through the investigation of a dry cough. Cureus, 2016, 8(11): e896.
3. Driessen AK, McGovern AE, Narula M, et al. Central mechanisms of airway sensation and cough hypersensitivity. Pulm Pharmacol Ther, 2017, S1094-5539(17)30016-0.
4. Molassiotis A, Smith JA, Mazzone P, et al. Symptomatic treatment of cough among adult patients with lung cancer: chest guidelines and expert panel report. Chest, 2017, 151(4):861-874.
5. 车国卫, 刘伦旭, 石应康. 加速康复外科临床应用现状与思考. 中国胸心血管外科临床杂志, 2016, 23(3): 211-215.0.
6. 车国卫, 李为民, 刘伦旭. 快速肺康复需要围手术期流程优化. 中国胸心血管外科临床杂志, 2016, 23(3): 216-220.0.
7. Liu L, Che G, Pu Q, et al. A new concept of endoscopic lung cancer resection: Single-direction thoracoscopic lobectomy. Surg Oncol, 2010, 19(2): e71-e77.
8. Zhi XY, Yu JM, Shi YK. Chinese guidelines on the diagnosis and treatment of primary lung cancer(2015 version). Cancer, 2015, 121(Suppl 17): 3165-3181.
9. 杨梅, 樊骏 ,周红霞, 等. 胸腔镜肺癌肺叶切除术后 16F 较 28F 胸腔引流管应用的临床优势. 中国肺癌杂志, 2015, 18(8): 512-517.0.
10. Gao YH, Guan WJ, Xu G, et al. Validation of the Mandarin Chinese version of the Leicester Cough Questionnaire in bronchiectasis. Int J Tuberc Lung Dis, 2014, 18(12): 1431-1437.
11. Raj AA, Pavord DI, Birring SS. Clinical cough IV:what is the minimal important difference for the Leicester Cough Questionnaire? Handb Exp Pharmacol, 2009, 187: 311-320.
12. Yousaf N, Lee KK, Jayaraman B, et al. The assessment of quality of life in acute cough with the Leicester Cough Questionnaire (LCQ-acute). Cough, 2011, 7(1): 4.
13. Molassiotis A, Smith JA, Bennett MI, et al. Clinical expert guidelines for the management of cough in lung cancer: report of a UK task group on cough. Cough, 2010, 6: 9. doi: 10.1186/1745-9974-6-9.
14. Harle AS, Blackhall FH, Smith JA, et al. Understanding cough and its management in lung cancer. Curr Opin Support Palliat Care, 2012, 6(2): 153-162.
15. Lee SY, Yoo JY, Kim JY, et al. Optimal effect-site concentration of remifentanil for preventing cough during removal of the double-lumen endotracheal tube from sevoflurane-remifentanil anesthesia: A prospective clinical trial. Medicine (Baltimore), 2016, 95(24): e3878.
16. Birring SS, Spinou A. How best to measure cough clinically. Curr Opin Pharmacol, 2015, 22: 37-40.
17. Wang K, Birring SS, Taylor K, et al. Montelukast for postinfectious cough in adults: a double-blind randomised placebo-controlled trial. Lancet Respir Med, 2014, 2(1): 35-43.
18. 黄佳, 罗清泉, 申屠阳,等. 右肺癌系统性清扫淋巴结术后顽固性咳嗽防治方法的探讨. 中国肺癌杂志, 2010, 13(10): 975-979.0.
19. 宋志芳, 韩兆杰, 林琳, 等. SF-36 量表评价胸外科住院患者生活质量的信度和效度. 中国胸心血管外科临床杂志, 2014, 21(2):164-167.0.
20. 李斌恺, 赖克方, 王法霞, 等. 慢性咳嗽患者的生活质量调查. 国际呼吸杂志, 2011, 31(5): 326-329.0.

Previous Article
Clinical implementation of robot assisted trans-subxiphoid (extended) thymectomy
Next Article
Surgical strategy for giant mediastinal mass

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Influencing factors of postoperative cough after lung resection in patients with lung cancer by video-assisted thoracic surgery: a single centre prospective study

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content