Current state of lung cancer with chronic obstructive pulmonary disease in China: A bibliometrics analysis_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

GAO Hua ¹ , ZHAO Ye ² , FENG Haiming ³ , SONG Tieniu ³ , YANG Jianbao ³ , JING Tao ³ , JIANG Peng ³ , LIN Junping ³ ,  LI Bin ³

1. Department of Outpatient, Lanzhou University Second Hospital, Lanzhou University Second Clinical Medical College, Lanzhou, 730030, P.R.China;
2. Respiratory Department, Lanzhou University First Hospital, Lanzhou University First Clinical Medical College, Lanzhou, 730030, P.R.China;
3. Department of Thoracic Surgery, Lanzhou University Second Hospital, Lanzhou University Second Clinical Medical College, Lanzhou, 730030, P.R.China;

Corresponding author：

LI Bin, Email: dr.leebin@outlook.com

Keywords：

Lung cancer; chronic obstructive pulmonary disease; visualization analysis; bibliometrics; research topics

DOI：

10.7507/1007-4848.201803054

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective To explore the research state and topics of lung cancer with chronic obstructive pulmonary disease (COPD) in China using the visualization methods. Methods Literature about lung cancer with COPD was searched through WanFang, CNKI, CBM, PubMed, The Cochrane Library and EMbase databases from inception to March 2018 by computer. We used BICOMS software to analyze the main information and produce co-word matrix, gCLUTO software to cluster, and NetDraw and Cytoscape software to draw the pictures. Results There were 304 studies related to lung cancer with COPD which originated from 173 journals including 23 indexed by Chinese Science Citation Database (CSCD) with 42 articles published, accounting for 13.8% of the total number of studies. There were 37 articles from 24 journals indexed by Science Citation Index (SCI) accounting for 12.2% of the total number of studies. The studies grew rapidly since 2012. The study involved 32 provinces, municipalities, and autonomous regions, among which Beijing, Sichuan, Shanghai, Guangzhou and Jiangsu provinces and cities were the main research areas. Sixty-nine high-frequency keywords were obtained with frequency 2 as the threshold, which was clustered into 5 categories by dual cluster analysis. Among them, topic 0 showed pathogenesis and radiological diagnosis of lung cancer with COPD, topic 1 was about the clinical characteristics of different pathological types of lung cancer with COPD and Chinese medicine treatment, topic 2 aimed at the impact of risk factors on surgical complications and the relationship between chemotherapy or targeted therapies and patient survival prognosis, topic 3 involved the pigenetic correlation between lung cancer and COPD and topic 4 was about clinical studies of perioperative comprehensive management of lung cancer patients with COPD. Conclusion The bibliometrics results show that there are considerable-amount achievements on lung cancer combined with COPD in China, and the researches have gradually increased since 2012. Horizontal research topics are extensive, and the focus of the study is to explore the perioperative comprehensive management and basic research of lung cancer with COPD, but the longitudinal themes need to be further studied. The results of some studies have not yet reached a consensus. There are few high-quality multi-center studies and a lack of clinical-directed achievement.

Citation： GAO Hua, ZHAO Ye, FENG Haiming, SONG Tieniu, YANG Jianbao, JING Tao, JIANG Peng, LIN Junping, LI Bin. Current state of lung cancer with chronic obstructive pulmonary disease in China: A bibliometrics analysis. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2019, 26(3): 233-244. doi: 10.7507/1007-4848.201803054 Copy

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1. Murray CJ, Lopez AD. Measuring the global burden of disease. N Engl J Med, 2013, 369(5): 448-457.
2. Wilson DO, Weissfeld JL, Balkan A, et al. Association of radiographic emphysema and airflow obstruction with lung cancer. Am J Respir Crit Care Med, 2008, 178(7): 738-744.
3. Denholm R, Schüz J, Straif K, et al. Is previous respiratory disease a risk factor for lung cancer? Am J Respir Crit Care Med, 2014, 190(5): 549-559.
4. Smith BM, Pinto L, Ezer N, et al. Emphysema detected on computed tomography and risk of lung cancer: a systematic review and meta-analysis. Lung Cancer, 2012, 77(1): 58-63.
5. Villar Álvarez F, Muguruza Trueba I, Belda Sanchis J, et al. Executive summary of the SEPAR recommendations for the diagnosis and treatment of non-small cell lung cancer. Arch Bronconeumol, 2016, 52(7): 378-388.
6. GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet, 2015, 385(9963): 117-171.
7. Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer, 2010, 127(12): 2893-2917.
8. Young RP, Hopkins RJ, Christmas T, et al. COPD prevalence is increased in lung cancer, independent of age, sex and smoking history. Eur Respir J, 2009, 34(2): 380-386.
9. Vineis P, Airoldi L, Veglia F, et al. Environmental tobacco smoke and risk of respiratory cancer and chronic obstructive pulmonary disease in former smokers and never smokers in the EPIC prospective study. BMJ, 2005, 330(7486): 277.
10. Skillrud DM, Offord KP, Miller RD. Higher risk of lung cancer in chronic obstructive pulmonary disease. A prospective, matched, controlled study. Ann Intern Med, 1986, 105(4): 503-507.
11. Calabrò E, Randi G, La Vecchia C, et al. Lung function predicts lung cancer risk in smokers: a tool for targeting screening programmes. Eur Respir J, 2010, 35(1): 146-151.
12. Schwartz AG, Cote ML, Wenzlaff AS, et al. Chronic obstructive lung diseases and risk of non-small cell lung cancer in women. J Thorac Oncol, 2009, 4(3): 291-299.
13. Henschke CI, Yip R, Boffetta P, et al. CT screening for lung cancer: Importance of emphysema for never smokers and smokers. Lung Cancer, 2015, 88(1): 42-47.
14. Schwartz AG, Lusk CM, Wenzlaff AS, et al. Risk of lung cancer associated with COPD phenotype based on quantitative image analysis. Cancer Epidemiol Biomarkers Prev, 2016, 25(9): 1341-1347.
15. Wang H, Yang L, Zou L, et al. Association between chronic obstructive pulmonary disease and lung cancer: a case-control study in Southern Chinese and a meta-analysis. PLoS One, 2012, 7(9): e46144.
16. Dai J, Yang P, Cox A, et al. Lung cancer and chronic obstructive pulmonary disease: From a clinical perspective. Oncotarget, 2017, 8(11): 18513-18524.
17. Dai J, Liu M, Swensen SJ, et al. Regional emphysema score predicting overall survival, quality of life, and pulmonary function recovery in early-stage lung cancer patients. J Thorac Oncol, 2017, 12(5): 824-832.
18. Dai J, Liu M, Jiang G, et al. The impact of chronic obstructive pulmonary disease on lung cancer survival: A meta-analysis. Arch Cancer Res, 2016, 4: 1.
19. Wasswa-Kintu S, Gan WQ, Man SF, et al. Relationship between reduced forced expiratory volume in one second and the risk of lung cancer: a systematic review and meta-analysis. Thorax, 2005, 60(7): 570-575.
20. Hersh CP, Washko GR, Jacobson FL, et al. Interobserver variability in the determination of upper lobe-predominant emphysema. Chest, 2007, 131(2): 424-431.
21. Li Y, Swensen SJ, Karabekmez LG, et al. Effect of emphysema on lung cancer risk in smokers: a computed tomography-based assessment. Cancer Prev Res (Phila), 2011, 4(1): 43-50.
22. de Torres JP, Bastarrika G, Wisnivesky JP, et al. Assessing the relationship between lung cancer risk and emphysema detected on low-dose CT of the chest. Chest, 2007, 132(6): 1932-1938.
23. Lowry KP, Gazelle GS, Gilmore ME, et al. Personalizing annual lung cancer screening for patients with chronic obstructive pulmonary disease: A decision analysis. Cancer, 2015, 121(10): 1556-1562.
24. Biswas A, Mehta HJ, Folch EE. Chronic obstructive pulmonary disease and lung cancer: inter-relationships. Curr Opin Pulm Med, 2018, 24(2): 152-160.
25. Yang P, Sun Z, Krowka MJ, et al. Alpha1-antitrypsin deficiency carriers, tobacco smoke, chronic obstructive pulmonary disease, and lung cancer risk. Arch Intern Med, 2008, 168(10): 1097-1103.
26. Zhao B, Han H, Chen J, et al. MicroRNA let-7c inhibits migration and invasion of human non-small cell lung cancer by targeting ITGB3 and MAP4K3. Cancer Lett, 2014, 342(1): 43-51.
27. Van Pottelberge GR, Mestdagh P, Bracke KR, et al. MicroRNA expression in induced sputum of smokers and patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 2011, 183(7): 898-906.
28. Young RP, Whitford W, Hopkins RJ. Telomere shortening in COPD and lung cancer: a pilot study in chronic smokers in D99. Novel translational biomarkers in lung cancers. Am Thoracic Soc, 2016: A7539-A7539.
29. Anzalone G, Arcoleo G, Montalbano AM, et al. Cigarette smoke alters the EZH2/DAB2IP expression in bronchial epithelial cells. A risk factor for lung cancer in COPD patients. Eur Respiratory Soc, 2016, 48(suppl 60): PA3995.
30. Dang X, Ma A, Yang L, et al. MicroRNA-26a regulates tumorigenic properties of EZH2 in human lung carcinoma cells. Cancer Genet, 2012, 205(3): 113-123.
31. Aoshiba K, Yokohori N, Nagai A. Alveolar wall apoptosis causes lung destruction and emphysematous changes. Am J Respir Cell Mol Biol, 2003, 28(5): 555-562.
32. Otsubo K, Goto H, Nishio M, et al. MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation. Oncogene, 2017, 36(29): 4201-4211.
33. Takahashi H, Ogata H, Nishigaki R, et al. Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation. Cancer Cell, 2010, 17(1): 89-97.
34. Rahman I, Adcock IM. Oxidative stress and redox regulation of lung inflammation in COPD. Eur Respir J, 2006, 28(1): 219-242.
35. Covey TM, Edes K, Coombs GS, et al. Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer. PLoS One, 2010, 5(10): e13545.
36. Ng Kee Kwong F, Nicholson AG, Harrison CL, et al. Is mitochondrial dysfunction a driving mechanism linking COPD to nonsmall cell lung carcinoma? Eur Respir Rev, 2017, 26(146): pii: 170040.
37. Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol, 2005, 6(11): 1133-1141.
38. Chen X, Wan J, Liu J, et al. Increased IL-17-producing cells correlate with poor survival and lymphangiogenesis in NSCLC patients. Lung Cancer, 2010, 69(3): 348-354.
39. Houghton AM. Mechanistic links between COPD and lung cancer. Nat Rev Cancer, 2013, 13(4): 233-245.
40. Shapiro SD, Goldstein NM, Houghton AM, et al. Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice. Am J Pathol, 2003, 163(6): 2329-2335.
41. Lamprecht B, Soriano JB, Studnicka M, et al. Determinants of underdiagnosis of COPD in national and international surveys. Chest, 2015, 148(4): 971-985.
42. Gershon AS, Hwee J, Chapman KR, et al. Factors associated with undiagnosed and overdiagnosed COPD. Eur Respir J, 2016, 48(2): 561-564.
43. Young RP, Hopkins RJ. Diagnosing COPD and targeted lung cancer screening. Eur Respir J, 2012, 40(4): 1063-1064.
44. de Torres JP, Marín JM, Casanova C, et al. Lung cancer in patients with chronic obstructive pulmonary disease-- incidence and predicting factors. Am J Respir Crit Care Med, 2011, 184(8): 913-919.
45. de-Torres JP, Wilson DO, Sanchez-Salcedo P, et al. Lung cancer in patients with chronic obstructive pulmonary disease. Development and validation of the COPD Lung Cancer Screening Score. Am J Respir Crit Care Med, 2015, 191(3): 285-291.
46. Gould MK. Lung cancer screening in individuals with chronic obstructive pulmonary disease. Finding the sweet spot. Am J Respir Crit Care Med, 2015, 192(9): 1027-1028.
47. Sin DD, Anthonisen NR, Soriano JB, et al. Mortality in COPD: Role of comorbidities. Eur Respir J, 2006, 28(6): 1245-1257.
48. Lung Health Study Research Group, Wise R, Connett J, et al. Effect of inhaled triamcinolone on the decline in pulmonary function in chronic obstructive pulmonary disease. N Engl J Med, 2000, 343(26): 1902-1909.
49. Putila J, Guo NL. Combining COPD with clinical, pathological and demographic information refines prognosis and treatment response prediction of non-small cell lung cancer. PLoS One, 2014, 9(6): e100994.
50. Hopkins RJ, Ko J, Gamble GD, et al. Lung cancer surgery for early stage non-small cell lung cancer: systematic review of mortality according to the presence of COPD. B110: pulmonary nodules and thoracic surgery: working across the aisle. Am Thoracic Soc, 2017: A4887.
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Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Current state of lung cancer with chronic obstructive pulmonary disease in China: A bibliometrics analysis

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