• Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China;
HU Jia, Email: humanjia@msn.com
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Pulmonary hypertension is a disease characterized by pulmonary artery pressure increased, with or without small artery pathological change, which ultimately leads to right heart failure or even death. Pulmonary hypertension seriously threatens to human health, however, the pathogenesis of pulmonary hypertension is unclear. Previous studies have found that bone morphogenetic protein (BMP) signaling system played an important role in the progress of pulmonary hypertension. In the current review, we describe the mechanism of BMP4 in the development of pulmonary hypertension.

Citation: QIAN Hong, HU Jia. Research progress of bone morphogenetic protein-4 in pulmonary vascular remodeling in patients with pulmonary hypertension. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2019, 26(3): 274-277. doi: 10.7507/1007-4848.201805064 Copy

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