GAO Manchen 1 , DUAN Fujian 2 , ZHANG Gejun 1 , XIE Yongquan 1 , WANG Shouzheng 1,3 , HU Xiaopeng 1 , HU Haibo 1 , WAN Junyi 1 , LUO Zhiling 4 , PAN Jiahua 3 , ZHANG Jing 1,5 , SONG Huijun 1,5 , XIONG Hui 5 , PAN Xiangbin 1,3
  • 1. Department of Structural Heart Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100037, P. R. China;
  • 2. Department of Echocardiography Imaging, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100037, P. R. China;
  • 3. Department of Structural Heart Disease, Fuwai Yunnan Cardiovascular Hospital, Kunming, 650102, P. R. China;
  • 4. Department of Echocardiography, Fuwai Yunnan Cardiovascular Hospital, Kunming, 650102, P. R. China;
  • 5. Department of Cardiac Surgery, Shenzhen Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, 518057, Guangdong, P. R. China;
PAN Xiangbin, Email: panxiangbin@fuwaihospital.org
Transcatheter edge-to-edge repair; mitral regurgitation; MitraClip
10.7507/1007-4848.202111088
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Objective To investigate the early clinical results of MitraClip system in domestic patients. Methods  We retrospectively analyzed the clinical data of 36 patients who underwent transcatheter edge-to-edge repair procedure using MitraClip system in Beijing Fuwai Hospital, Shenzhen Fuwai Hospital and Fuwai Yunnan Cardiovascular Hospital between January and June 2021. There were 24 males and 12 females, with a median age of 70 (47-86) years. Ten (27.8%) patients had 3+ mitral regurgitation (MR) and 26 (72.2%) patients had 4+ MR preoperatively. Results All procedures were successfully performed. The reduction in MR was 2+ at least immediately after surgery, and 91.7% of patients had MR≤2+ at 3 days postoperatively. There was no statistical difference in left ventricular ejection fraction change postoperatively. Forward velocity and peak gradient of mitral valve were increased after the procedure. Mean gradient of mitral valve were increased at 3 days postoperatively than immediately after surgery (P<0.001). Two patients had acute pericardial effusion intraoperatively, and received pericardial puncture and drainage immediately. Conclusion MitraClip system has been applied well in domestic patients and can significantly improve MR. This sutdy has a good consistency with foreign studies, and the early results are satisfactory.

Citation： GAO Manchen, DUAN Fujian, ZHANG Gejun, XIE Yongquan, WANG Shouzheng, HU Xiaopeng, HU Haibo, WAN Junyi, LUO Zhiling, PAN Jiahua, ZHANG Jing, SONG Huijun, XIONG Hui, PAN Xiangbin. Primary practice of transcatheter edge-to-edge repair for mitral regurgitation: Early results of MitraClip in multiple centers. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2022, 29(5): 547-552. doi: 10.7507/1007-4848.202111088 Copy

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