YANG Hang , ZHENG Huiping , FENG Haibo , ZHAO Hong , LING Yunpeng
  • Department of Cardiac Surgery, Peking University Third Hospital, Beijing, 100191, P. R. China;
LING Yunpeng, Email: micsling@pku.edu.cn
Mitral regurgitation; transapical mitral valve repair; LifeClip system
10.7507/1007-4848.202112085
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Objective To evaluate the safety and efficacy of transapical mitral valve repair with moderate-to-severe or severe mitral regurgitation (MR) by using LifeClip system. Methods  We retrospectively analyzed the clinical data of 7 symptomatic patients with moderate-to-severe or severe MR who received transapical mitral valve repair by using the LifeClip system in our hospital from July to November 2021. There were 5 males and 2 females with an average age of 76.0±7.5 years. Results There were 2 patients with degenerative MR and 5 patients with functional MR. All of the procedures were successful and 6 patients received 1 LifeClip while the other one patient received 2. The operation time was 135.7±46.9 min, the mechanical ventilation time was 12 (3, 14) h, and the hospital stay time was 18.1±4.1 d. No serious complications or death occurred during the perioperative or follow-up period. MR reduction by ≥2 grades was achieved in all the patients at the one-month follow-up. The classification of cardiac function was improved in varying degrees. Conclusion  Transapical mitral valve repair using the LifeClip system shows good safety and efficacy for severe MR patients, and MR degree is significantly improved at early follow-up. However, the benefit of LifeClip should be validated in a larger sample size of Chinese population and through long-term follow-up.

Citation： YANG Hang, ZHENG Huiping, FENG Haibo, ZHAO Hong, LING Yunpeng. Transapical mitral valve repair with LifeClip system: Early outcome of a single center. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2022, 29(5): 572-576. doi: 10.7507/1007-4848.202112085 Copy

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