甲状旁腺全切除术治疗继发性甲状旁腺功能亢进12例分析_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 王涛 ¹ , 张立洪 ¹ , 邱晶晶 ¹ , 芮坤 ¹ , 冯影 ¹ , 顾继礼 ¹ , 李海涛 ² , 余健 ³

1. ;
2. ;
3. ;

Corresponding author：

王涛, Email: txwangt168@sina.com

Keywords：

继发性甲状旁腺功能亢进; 甲状旁腺全切除术

DOI：

10.7507/1007-9424.20150393

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

目的总结应用甲状旁腺全切除且不移植手术治疗继发性甲状旁腺功能亢进（SHPT）在围手术期的处理经验。方法对我院2012年12月至2015年1月期间12例SHPT患者行甲状旁腺全切除且不移植手术的疗效进行回顾性分析，比较术前、术后血甲状旁腺激素（PTH）、血钙、血磷、血清碱性磷酸酶（AKP）值及临床症状改善情况。结果 12例患者术后骨痛、皮肤瘙痒症状明显缓解，血PTH值术后迅速下降，6个月后恢复至正常范围，血钙均迅速下降并低于正常，AKP指标下降缓慢，血磷指标恢复正常。随访1～2年未出现复发。1例患者于术后4个月死于脑血管意外。结论甲状旁腺全切除且不移植治疗SHPT安全、有效，低钙血症是术后防治重点，多学科协作治疗有利于患者平稳渡过围手术期。

Citation： 王涛, 张立洪, 邱晶晶, 芮坤, 冯影, 顾继礼, 李海涛, 余健. 甲状旁腺全切除术治疗继发性甲状旁腺功能亢进12例分析. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2015, 22(12): 1513-1514. doi: 10.7507/1007-9424.20150393 Copy

1.	张凌, 闫彩芸, 姚力.难治性继发性甲状旁腺功能亢进症的外科治疗.中国血液净化, 2012, 11(7): 349-351.
2.	马丽洁, 赵素梅, 刘婧, 等.甲状旁腺切除术对血液透析患者合并继发性甲状旁腺功能亢进骨代谢及骨密度的影响.中华肾脏病杂志, 2015, 31(1): 13-18.
3.	张海东, 龚单春, 刘亚群, 等.甲状腺全切手术中甲状旁腺的保护.中华耳鼻咽喉头颈外科杂志, 2014, 49(11): 889-892.
4.	邵选, 潘永海, 吴成亮, 等.精细被膜解剖法原位保留甲状旁腺的临床应用.实用医学杂志, 2009, 25(13): 2110-2111.
5.	王松, 代文杰.困难甲状旁腺手术的技术要点.中国普外基础与临床杂志, 2013, 20(1): 92-94.
6.	陈隽, 王家东.应用99mTc-MIBI术中定位的甲状旁腺切除术治疗继发性甲状旁腺功能亢进的研究.中华内分泌外科杂志, 2012, 6(1): 39-41, 45.
7.	Sakman G, Parsak CK, Balal M, et al. Outcomes of total parathyroi-dectomy with autotransplantation versus subtotal parathyroidec-tomy with routine addition of thymectomy to both groups: single center experience of secondary hyperparathyroidism. Balkan Med J, 2014, 31(1): 77-82.
8.	Jia X, Wang R, Zhang C, et al. Long-term outcomes of total parath-yroidectomy with or without autoimplantation for hyperparathyroi-dism in chronic kidney disease: a meta-analysis. Ther Apher Dial, 2015 May 6. [Epub ahead of print].
9.	Conzo G, Perna A, Candela G, et al. Long-term outcomes following "presumed" total parathyroidectomy for secondary hyperparathyroi-dism of chronic kidney disease. G Chir, 2012, 33(11/12): 379-382.
10.	Pattou FN, Pellissier LC, Noël C, et al. Supernumerary parathyroid glands: frequency and surgical significance in treatment of renal hyperparathyroidism. World J Surg, 2000, 24(11): 1330-1334.
11.	Iwamoto N, Sato N, Nishida M, et al. Total parathyroidectomy improves survival of hemodialysis patients with secondary hyper-parathyroidism. J Nephrol, 2012, 25(5): 755-763.
12.	Oltmann SC, Madkhali TM, Sippel RS, et al. Kidney disease impro-ving global outcomes guidelines and parathyroidectomy for renal hyperparathyroidism. J Surg Res, 2015 Apr 18. [Epub ahead of print].
13.	Coulston JE, Egan R, Willis E, et al. Total parathyroidectomy without autotransplantation for renal hyperparathyroidism. Br J Surg, 2010, 97(11): 1674-1679.
14.	Abboud B, Sleilaty G, Ayoub S, et al. Intrathyroid parathyroid adenoma in primary hyperparathyroidism: can it be predicted preoperatively? World J Surg, 2007, 31(4): 817-823.
15.	Kuo LE, Wachtel H, Karakousis G, et al. Parathyroidectomy in dialysis patients. J Surg Res, 2014, 190(2): 554-558.

1. 张凌, 闫彩芸, 姚力.难治性继发性甲状旁腺功能亢进症的外科治疗.中国血液净化, 2012, 11(7): 349-351.
2. 马丽洁, 赵素梅, 刘婧, 等.甲状旁腺切除术对血液透析患者合并继发性甲状旁腺功能亢进骨代谢及骨密度的影响.中华肾脏病杂志, 2015, 31(1): 13-18.
3. 张海东, 龚单春, 刘亚群, 等.甲状腺全切手术中甲状旁腺的保护.中华耳鼻咽喉头颈外科杂志, 2014, 49(11): 889-892.
4. 邵选, 潘永海, 吴成亮, 等.精细被膜解剖法原位保留甲状旁腺的临床应用.实用医学杂志, 2009, 25(13): 2110-2111.
5. 王松, 代文杰.困难甲状旁腺手术的技术要点.中国普外基础与临床杂志, 2013, 20(1): 92-94.
6. 陈隽, 王家东.应用99mTc-MIBI术中定位的甲状旁腺切除术治疗继发性甲状旁腺功能亢进的研究.中华内分泌外科杂志, 2012, 6(1): 39-41, 45.
7. Sakman G, Parsak CK, Balal M, et al. Outcomes of total parathyroi-dectomy with autotransplantation versus subtotal parathyroidec-tomy with routine addition of thymectomy to both groups: single center experience of secondary hyperparathyroidism. Balkan Med J, 2014, 31(1): 77-82.
8. Jia X, Wang R, Zhang C, et al. Long-term outcomes of total parath-yroidectomy with or without autoimplantation for hyperparathyroi-dism in chronic kidney disease: a meta-analysis. Ther Apher Dial, 2015 May 6. [Epub ahead of print].
9. Conzo G, Perna A, Candela G, et al. Long-term outcomes following "presumed" total parathyroidectomy for secondary hyperparathyroi-dism of chronic kidney disease. G Chir, 2012, 33(11/12): 379-382.
10. Pattou FN, Pellissier LC, Noël C, et al. Supernumerary parathyroid glands: frequency and surgical significance in treatment of renal hyperparathyroidism. World J Surg, 2000, 24(11): 1330-1334.
11. Iwamoto N, Sato N, Nishida M, et al. Total parathyroidectomy improves survival of hemodialysis patients with secondary hyper-parathyroidism. J Nephrol, 2012, 25(5): 755-763.
12. Oltmann SC, Madkhali TM, Sippel RS, et al. Kidney disease impro-ving global outcomes guidelines and parathyroidectomy for renal hyperparathyroidism. J Surg Res, 2015 Apr 18. [Epub ahead of print].
13. Coulston JE, Egan R, Willis E, et al. Total parathyroidectomy without autotransplantation for renal hyperparathyroidism. Br J Surg, 2010, 97(11): 1674-1679.
14. Abboud B, Sleilaty G, Ayoub S, et al. Intrathyroid parathyroid adenoma in primary hyperparathyroidism: can it be predicted preoperatively? World J Surg, 2007, 31(4): 817-823.
15. Kuo LE, Wachtel H, Karakousis G, et al. Parathyroidectomy in dialysis patients. J Surg Res, 2014, 190(2): 554-558.

Previous Article
乳房Paget病16例临床分析
Next Article
无张力疝修补术围手术期是否使用抗菌药物预防切口感染？

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

甲状旁腺全切除术治疗继发性甲状旁腺功能亢进12例分析

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content