• Department of General Surgery of Renhe Hospital, Three Gorges University, Yichang 443002, Hubei Province, China;
ZHANGXian-lin, Email: 706456093@qq.com
Export PDF Favorites Scan Get Citation

Objective To investigate the relationship between insulin-like growth factor binding protein (IGFBP) gene with pancreatic cancer. Methods The relevant literatures at home and abroad in recent years were reviewed. From the pancreatic cancer related genes, IGFBP related tumors and the correlation between IGFBP and pancreatic cancer research and other aspects of the previous research results were summaried. Results Most of the studies suggested that IGFBP could inhibit the function of tumor cells through the IGF dependent pathway, but the deletion or mutation of IGFBP gene and its regulation mechanism are still unclear. Conclusion IGFBP is closely related to the tumor, but its specific effects and mechanism of pancreatic cancer has not been settled. In order to affect the degree of cell differentiation, regulation of tumor growth and metastasis probability through the change of endogenous IGFBP gene level, the further studie is needed.

Citation: TAN Zhi-hui, ZHANG Xian-lin. Research Progress of Relationship Between IGFBP Gene and Pancreatic Cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2016, 23(10): 1285-1288. doi: 10.7507/1007-9424.20160330 Copy

  • Previous Article

    胸腔镜结扎胸导管治疗右颈淋巴结清扫术后乳糜漏1例报道
  • Next Article

    Pulmonary Atresia and Ventricular Septal Defect Repair with Pericardial Tube: A Single Center Retrospective Follow-up Study