Clinical Efficacy of Percutaneous Nephroscope in Treatment of Patients with Severe Acute Pancreatitis_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 YANGGuo-chun , CHENHong-gang , LIUQi-fei , JIAHong-gang , LIUHong-yan

Department of Emergency Surgery, Affiliated Hospital of Shandong Academy of Medical Sciences, Ji'nan 250031, Shandong Province, China;

Corresponding author：

YANGGuo-chun, Email: yangguochun25@yeah.net

Keywords：

Percutaneous nephroscope; Severe acute pancreatitis; Inflammatory reaction; Complications

DOI：

10.7507/1007-9424.20160349

Video：

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Objective To investigate clinical efficacy of percutaneous nephroscope in treatment of patients with severe acute pancreatitis (SAP). Methods Eighty-six patients with SAP in this hospital from August 2012 to November 2015 were selected, which were divided into percutaneous nephroscope treatment group (43 cases) and laparotomy treat-ment group (43 cases) according to the difference of therapy modality. The conventional drug therapy was performed for all of them. The postoperative recovery, content of serum C reactive protein (CRP) on day 14 after operation, and post-operative complications were observed in these two groups. Results ① The abdominal pain relief time, postoperative bowel sounds recovery time, normal body temperature recovery time, and postoperative hospitalization time in the percu-taneous nephroscope treatment group were significantly shorter than those in the laparotomy treatment group (P<0.05). ② The contents of serum CRP in the percutaneous nephroscope treatment group and in the laparotomy treatment group on day 14 after operation were significantly lower than those on day 1 before operation[(8.35±2.13) mg/L versus (31.44±3.45) mg/L, P<0.05; (16.42±2.44) mg/L versus (32.09±2.98) mg/L, P<0.05]. On day 14 after operation, the content of serum CRP in the percutaneous nephroscope treatment group was significantly lower than that in the laparotomy treat-ment group[(8.35±2.13) mg/L versus (16.42±2.44) mg/L, P<0.05]. ③ The incidence rate of postoperative complications in the percutaneous nephroscope treatment group was significantly lower than that in the laparotomy treatment group[14.0% (6/43) versus 32.6% (14/43), P<0.05]. Conclusion Percutaneous nephroscope in treatment of patients with SAP is effect, it has advantages of shorter hospital stay and early recovery, which could reduce incidence of postoperative complications, and it's mechanism might be related to systemic inflammatory response.

Citation： YANGGuo-chun, CHENHong-gang, LIUQi-fei, JIAHong-gang, LIUHong-yan. Clinical Efficacy of Percutaneous Nephroscope in Treatment of Patients with Severe Acute Pancreatitis. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2016, 23(11): 1366-1369. doi: 10.7507/1007-9424.20160349 Copy

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2.	Li Z, Xia C, Zhang L, et al. Peritoneal lavage for severe acute pancrea-titis:a meta-analysis and systematic review. Pancreas, 2016, 45(6):806-813.
3.	姚兰杰. 重症急性胰腺炎的临床治疗方法与效果观察. 中国实用医刊, 2015, 42(3):29-30.
4.	Wang G, Zhang J, Xu C, et al. Inhibition of SOCs attenuates acute lung injury induced by severe acute pancreatitis in rats and PMVECs injury induced by lipopolysaccharide. Inflammation, 2016, 39(3):1049-1058.
5.	Shavakhi A, Khodadustan M, Tamizifar B. The effect of prophylactic peripapillary administration of methylprednisolone in reducing the risk and severity of postendoscopic retrograde cholangiopancreatog-raphy pancreatitis:A double blind clinical trial. J Res Med Sci, 2015, 20(9):850-854.
6.	邱庆文. 重症急性胰腺炎患者腹腔镜手术围术期胃肠激素及机体应激状态变化观察. 中南医学科学杂志, 2015, 17(6):675-678.
7.	文毅, 许芳怡, 康娟. 容积敏感性氯通道在急性胰腺炎早期的应用研究. 浙江临床医学, 2015, 22(4):516-517.
8.	王瑞江. 重症胰腺炎合并肠梗阻的治疗体会. 医学临床研究, 2013, 30(1):56-57.
9.	Tan CL, Zhang H, Li KZ. Single center experience in selecting the laparoscopic Frey procedure for chronic pancreatitis. World J Gastroenterol, 2015, 21(44):12644-12652.
10.	张晓东. 复发性胆源性胰腺炎应用十二指肠镜联合腹腔镜的疗效分析. 中国现代医生, 2015, 53(23):82-84.
11.	Banday IA, Gattoo I, Khan AM, et al. Modified computed tomogra-phy severity index for evaluation of acute pancreatitis and its correla-tion with clinical outcome:A Tertiary Care Hospital Based Observa-tional Study. J Clin Diagn Res, 2015, 9(8):TC01-TC05.
12.	辛宪磊, 蔡守旺, 刘志伟, 等. 经皮肾镜治疗重症急性胰腺炎术后残余感染的体会. 中华外科杂志, 2015, 53(9):676-679.
13.	练继文, 肖志伟. 经皮肾镜治疗胰腺周围脓肿体会(附12例报告). 中国现代药物应用, 2015, 9(18):23-24.
14.	Gormezano NW, Otsuzi CI, Barros DL, et al. Macrophage activation syndrome:A severe and frequent manifestation of acute pancreatitis in 362 childhood-onset compared to 1 830 adult-onset systemic lupus erythematosus patients. Semin Arthritis Rheum, 2016, 45(6):706-710.
15.	杨涓, 郑盛, 张帆, 等. 不同评分系统早期预测急性胰腺炎病情严重程度的比较研究. 中国医药导报, 2016, 13(2):133-137.
16.	徐涛. 手术与非手术治疗重症急性胰腺炎疗效比较. 中外医学研究, 2015, 13(12):142-142, 143.
17.	石云, 赵玉芳. 经皮肾镜治疗急性坏死性胰腺炎后的护理. 实用医技杂志, 2015, 22(1):106-109.
18.	刘路培, 刘明祥, 罗毅. 重症胰腺炎患者感染的临床分析. 中华医院感染学杂志, 2015, 25(17):4000-4002.
19.	Wei AL, Guo Q, Wang MJ, et al. Early complications after interven-tions in patients with acute pancreatitis. World J Gastroenterol, 2016, 22(9):2828-2836.
20.	Cavicchioli L, Zappulli V, Beffagna G, et al. Histopathological and immunohistochemical study of exocrine and endocrine pancreatic lesions in avian influenza A experimentally infected turkeys showing evidence of pancreatic regeneration. Avian Pathol, 2015, 44(6):498-508.
21.	徐笑群. 重症急性胰腺炎合并感染患者降钙素原检测的临床意义. 中国实用医刊, 2015, 42(8):46-47.
22.	周波, 戴飞跃, 翁国虎. 急性胰腺炎的诊疗进展. 现代中西医结合杂志, 2015, 17(5):565-567.

1. 杜奕奇, 李兆申. 2015版中国急性胰腺炎MDT共识意见解读. 中华胰腺病杂志, 2015, 15(5):289-291.
2. Li Z, Xia C, Zhang L, et al. Peritoneal lavage for severe acute pancrea-titis:a meta-analysis and systematic review. Pancreas, 2016, 45(6):806-813.
3. 姚兰杰. 重症急性胰腺炎的临床治疗方法与效果观察. 中国实用医刊, 2015, 42(3):29-30.
4. Wang G, Zhang J, Xu C, et al. Inhibition of SOCs attenuates acute lung injury induced by severe acute pancreatitis in rats and PMVECs injury induced by lipopolysaccharide. Inflammation, 2016, 39(3):1049-1058.
5. Shavakhi A, Khodadustan M, Tamizifar B. The effect of prophylactic peripapillary administration of methylprednisolone in reducing the risk and severity of postendoscopic retrograde cholangiopancreatog-raphy pancreatitis:A double blind clinical trial. J Res Med Sci, 2015, 20(9):850-854.
6. 邱庆文. 重症急性胰腺炎患者腹腔镜手术围术期胃肠激素及机体应激状态变化观察. 中南医学科学杂志, 2015, 17(6):675-678.
7. 文毅, 许芳怡, 康娟. 容积敏感性氯通道在急性胰腺炎早期的应用研究. 浙江临床医学, 2015, 22(4):516-517.
8. 王瑞江. 重症胰腺炎合并肠梗阻的治疗体会. 医学临床研究, 2013, 30(1):56-57.
9. Tan CL, Zhang H, Li KZ. Single center experience in selecting the laparoscopic Frey procedure for chronic pancreatitis. World J Gastroenterol, 2015, 21(44):12644-12652.
10. 张晓东. 复发性胆源性胰腺炎应用十二指肠镜联合腹腔镜的疗效分析. 中国现代医生, 2015, 53(23):82-84.
11. Banday IA, Gattoo I, Khan AM, et al. Modified computed tomogra-phy severity index for evaluation of acute pancreatitis and its correla-tion with clinical outcome:A Tertiary Care Hospital Based Observa-tional Study. J Clin Diagn Res, 2015, 9(8):TC01-TC05.
12. 辛宪磊, 蔡守旺, 刘志伟, 等. 经皮肾镜治疗重症急性胰腺炎术后残余感染的体会. 中华外科杂志, 2015, 53(9):676-679.
13. 练继文, 肖志伟. 经皮肾镜治疗胰腺周围脓肿体会(附12例报告). 中国现代药物应用, 2015, 9(18):23-24.
14. Gormezano NW, Otsuzi CI, Barros DL, et al. Macrophage activation syndrome:A severe and frequent manifestation of acute pancreatitis in 362 childhood-onset compared to 1 830 adult-onset systemic lupus erythematosus patients. Semin Arthritis Rheum, 2016, 45(6):706-710.
15. 杨涓, 郑盛, 张帆, 等. 不同评分系统早期预测急性胰腺炎病情严重程度的比较研究. 中国医药导报, 2016, 13(2):133-137.
16. 徐涛. 手术与非手术治疗重症急性胰腺炎疗效比较. 中外医学研究, 2015, 13(12):142-142, 143.
17. 石云, 赵玉芳. 经皮肾镜治疗急性坏死性胰腺炎后的护理. 实用医技杂志, 2015, 22(1):106-109.
18. 刘路培, 刘明祥, 罗毅. 重症胰腺炎患者感染的临床分析. 中华医院感染学杂志, 2015, 25(17):4000-4002.
19. Wei AL, Guo Q, Wang MJ, et al. Early complications after interven-tions in patients with acute pancreatitis. World J Gastroenterol, 2016, 22(9):2828-2836.
20. Cavicchioli L, Zappulli V, Beffagna G, et al. Histopathological and immunohistochemical study of exocrine and endocrine pancreatic lesions in avian influenza A experimentally infected turkeys showing evidence of pancreatic regeneration. Avian Pathol, 2015, 44(6):498-508.
21. 徐笑群. 重症急性胰腺炎合并感染患者降钙素原检测的临床意义. 中国实用医刊, 2015, 42(8):46-47.
22. 周波, 戴飞跃, 翁国虎. 急性胰腺炎的诊疗进展. 现代中西医结合杂志, 2015, 17(5):565-567.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Clinical Efficacy of Percutaneous Nephroscope in Treatment of Patients with Severe Acute Pancreatitis

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