Clinical analysis of long-term effect of duodenum-preserving pancreatic head resection <i>versus</i> pancreaticoduodenectomy: a single center experience_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

CHENG Kun ¹ , SUN Yonghui ¹ , LIN Hai ¹ , DING Nan ² , XU Jiaqi ¹ ,  CHEN Qilong ¹

1. Department of Pancreas Surgery, Digestion and Vascular Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, P. R. China;
2. Department of Pharmacy, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, P. R. China;

Corresponding author：

CHEN Qilong, Email: chenqilong651003@sohu.com

Keywords：

duodenum-preserving pancreatic head resection; pancreaticoduodenectomy; chronic pancreatitis; pancreatic tumor

DOI：

10.7507/1007-9424.201912113

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To summarize and analyze the long-term clinical effect of duodenum-preserving pancreatic head resection (DPPHR) versus pancreaticoduodenectomy.Methods The clinical data of 102 patients who underwent DPPHR (n=35) or pancreaticoduodenectomy (n=67) from January 2014 to December 2019 in The First Affiliated Hospital of Xinjiang Medical University were analyzed retrospectively.Results The operations of patients in the DPPHR group and the PD group were successfully complete, no one died during operation or perioperative period. The weight gain in one year after operation and incidences of exocrine dysfunction in the DPPHR group were all better than those of the PD group (P<0.05), but there was no significant difference on the other complications between the two groups (P>0.05). The pain score, diarrhea score, and the overall health status score in one year after operation significantly improved in the DPPHR group than those in the PD group (P<0.05).Conclusion DPPHR is more beneficial to improve the quality of life after operation, and is a better surgical procedure for benign and low-grade malignant diseases of pancreatic head.

Citation： CHENG Kun, SUN Yonghui, LIN Hai, DING Nan, XU Jiaqi, CHEN Qilong. Clinical analysis of long-term effect of duodenum-preserving pancreatic head resection versus pancreaticoduodenectomy: a single center experience. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2020, 27(10): 1211-1215. doi: 10.7507/1007-9424.201912113 Copy

1.	Whipple AO, Parsons WB, Mullins CR. Treatment of carcinoma of the ampulla of vater. Ann Surg, 1935, 102(4): 763-779.
2.	Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin, 2019, 69(1): 7-34.
3.	Narayanan S, Martin AN, Turrentine FE, <italic>et al</italic>. Mortality after pancreaticoduodenectomy: assessing early and late causes of patient death. J Surg Res, 2018, 231: 304-308.
4.	Morales Soriano R, Esteve Pérez N, Tejada Gavela S, <italic>et al</italic>. Outcomes of an enhanced recovery after surgery programme for pancreaticoduodenectomy. Cir Esp, 2015, 93(8): 509-515.
5.	Beger HG, Krautzberger W, Bittner R, <italic>et al</italic>. Duodenum-preserving resection of the head of the pancreas in patients with severe chronic pancreatitis. Surgery, 1985, 97(4): 467-473.
6.	Gloor B, Friess H, Uhl W, <italic>et al</italic>. A modified technique of the Beger and Frey procedure in patients with chronic pancreatitis. Dig Surg, 2001, 18(1): 21-25.
7.	Takada T, Yasuda H, Uchiyama K, <italic>et al</italic>. Duodenum-preserving pancreatoduodenostomy. A new technique for complete excision of the head of the pancreas with preservation of biliary and alimentary integrity. Hepatogastroenterology, 1993, 40(4): 356-359.
8.	Takada T, Yasuda H, Uchiyama K, <italic>et al</italic>. Complete duodenum-preserving resection of the head of the pancreas with preservation of the biliary tract. J Hep Bil Panc Surg, 1995, 2(1): 32-37.
9.	Imaizumi T, Hanyu F, Suzuki M. A new procedure for duodenum-preserving total resection of the head of the pancreas with pancreaticocholedochoduodenostomy. Stand Panc Surg, 1993: 464-470.
10.	孙永辉, 程坤, 陈启龙. 保留十二指肠胰头切除术的临床应用及进展. 中国普外基础与临床杂志, 2019, 26(10): 1259-1264.
11.	张太平, 曹喆, 赵玉沛. 慢性胰腺炎合并胰头肿块的外科治疗策略. 中国普外基础与临床杂志, 2016, 23(6): 644-646.
12.	刘续宝. 慢性胰腺炎的胰头炎性包块的外科治疗. 中国普外基础与临床杂志, 2013, 20(2): 121-123.
13.	Beger HG. Benign tumors of the pancreas-radical surgery <italic>versus</italic> parenchyma-sparing local resection-the challenge facing surgeons. J Gastrointest Surg, 2018, 22(3): 562-566.
14.	Strobel O, Büchler MW. Pancreatoduodenectomy <italic>vs</italic> duodenum-preserving pancreatic head resection for chronic pancreatitis. Chirurg, 2019, 90(Suppl 2): 77.
15.	Beger HG, Mayer B, Poch B. Duodenum-preserving pancreatic head resection: a local parenchyma-sparing treatment of benign and premalignant tumors of the pancreatic head. Chirurg, 2019, 90(9): 736-743.
16.	Ayres Pereira M, Chio IIC. Metastasis in pancreatic ductal adenocarcinoma: current standing and methodologies. Genes (Basel), 2019, 11(1): E6.
17.	Diener MK, Hüttner FJ, Kieser M, <italic>et al</italic>. Partial pancreatoduodenectomy <italic>versus</italic> duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial. Lancet, 2017, 390(10099): 1027-1037.
18.	董志毅. 保留十二指肠的胰头切除术在胰头部良性病变中的应用及对术后生活质量的影响研究. 中华普外科手术学杂志 (电子版), 2017, 11(6): 528-530.
19.	洪德飞, 林志川, 张宇华, 等. 保留十二指肠和胆管完整性胰头切除术 31 例报告. 中华肝胆外科杂志, 2017, 23(3): 176-180.
20.	刘翔琪, 董岿然, 柳龚堡, 等. 保留十二指肠胰头肿块切除术在儿童胰头肿瘤治疗中的应用. 中华小儿外科杂志, 2017, 38(2): 103-106.
21.	王金湖, 茅君卿, 蔡嘉斌, 等. 保留十二指肠的胰头肿瘤切除术在儿童胰头肿瘤治疗中的应用. 浙江医学, 2019, 41(18): 1989-1991, 前插 5.
22.	Beger HG, Nakao A, Mayer B, <italic>et al</italic>. Duodenum-preserving total and partial pancreatic head resection for benign tumors–systematic review and meta-analysis. Pancreatology, 2015, 15(2): 167-178.
23.	孙永辉, 张晓晶, 林海, 等. 保留十二指肠的胰头切除术与胰十二指肠切除术治疗慢性胰腺炎疗效的 Meta 分析. 中华内分泌外科杂志, 2019, 13(3): 249-255.
24.	Zhao X, Cui N, Wang X, <italic>et al</italic>. Surgical strategies in the treatment of chronic pancreatitis: an updated systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore), 2017, 96(9): e6220.
25.	李建国, 王渊全, 陈谭根, 等. 保留十二指肠和胆管的胰头全切除术. 中华消化外科杂志, 2014, 13(11): 898-901.

1. Whipple AO, Parsons WB, Mullins CR. Treatment of carcinoma of the ampulla of vater. Ann Surg, 1935, 102(4): 763-779.
2. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin, 2019, 69(1): 7-34.
3. Narayanan S, Martin AN, Turrentine FE, <italic>et al</italic>. Mortality after pancreaticoduodenectomy: assessing early and late causes of patient death. J Surg Res, 2018, 231: 304-308.
4. Morales Soriano R, Esteve Pérez N, Tejada Gavela S, <italic>et al</italic>. Outcomes of an enhanced recovery after surgery programme for pancreaticoduodenectomy. Cir Esp, 2015, 93(8): 509-515.
5. Beger HG, Krautzberger W, Bittner R, <italic>et al</italic>. Duodenum-preserving resection of the head of the pancreas in patients with severe chronic pancreatitis. Surgery, 1985, 97(4): 467-473.
6. Gloor B, Friess H, Uhl W, <italic>et al</italic>. A modified technique of the Beger and Frey procedure in patients with chronic pancreatitis. Dig Surg, 2001, 18(1): 21-25.
7. Takada T, Yasuda H, Uchiyama K, <italic>et al</italic>. Duodenum-preserving pancreatoduodenostomy. A new technique for complete excision of the head of the pancreas with preservation of biliary and alimentary integrity. Hepatogastroenterology, 1993, 40(4): 356-359.
8. Takada T, Yasuda H, Uchiyama K, <italic>et al</italic>. Complete duodenum-preserving resection of the head of the pancreas with preservation of the biliary tract. J Hep Bil Panc Surg, 1995, 2(1): 32-37.
9. Imaizumi T, Hanyu F, Suzuki M. A new procedure for duodenum-preserving total resection of the head of the pancreas with pancreaticocholedochoduodenostomy. Stand Panc Surg, 1993: 464-470.
10. 孙永辉, 程坤, 陈启龙. 保留十二指肠胰头切除术的临床应用及进展. 中国普外基础与临床杂志, 2019, 26(10): 1259-1264.
11. 张太平, 曹喆, 赵玉沛. 慢性胰腺炎合并胰头肿块的外科治疗策略. 中国普外基础与临床杂志, 2016, 23(6): 644-646.
12. 刘续宝. 慢性胰腺炎的胰头炎性包块的外科治疗. 中国普外基础与临床杂志, 2013, 20(2): 121-123.
13. Beger HG. Benign tumors of the pancreas-radical surgery <italic>versus</italic> parenchyma-sparing local resection-the challenge facing surgeons. J Gastrointest Surg, 2018, 22(3): 562-566.
14. Strobel O, Büchler MW. Pancreatoduodenectomy <italic>vs</italic> duodenum-preserving pancreatic head resection for chronic pancreatitis. Chirurg, 2019, 90(Suppl 2): 77.
15. Beger HG, Mayer B, Poch B. Duodenum-preserving pancreatic head resection: a local parenchyma-sparing treatment of benign and premalignant tumors of the pancreatic head. Chirurg, 2019, 90(9): 736-743.
16. Ayres Pereira M, Chio IIC. Metastasis in pancreatic ductal adenocarcinoma: current standing and methodologies. Genes (Basel), 2019, 11(1): E6.
17. Diener MK, Hüttner FJ, Kieser M, <italic>et al</italic>. Partial pancreatoduodenectomy <italic>versus</italic> duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial. Lancet, 2017, 390(10099): 1027-1037.
18. 董志毅. 保留十二指肠的胰头切除术在胰头部良性病变中的应用及对术后生活质量的影响研究. 中华普外科手术学杂志 (电子版), 2017, 11(6): 528-530.
19. 洪德飞, 林志川, 张宇华, 等. 保留十二指肠和胆管完整性胰头切除术 31 例报告. 中华肝胆外科杂志, 2017, 23(3): 176-180.
20. 刘翔琪, 董岿然, 柳龚堡, 等. 保留十二指肠胰头肿块切除术在儿童胰头肿瘤治疗中的应用. 中华小儿外科杂志, 2017, 38(2): 103-106.
21. 王金湖, 茅君卿, 蔡嘉斌, 等. 保留十二指肠的胰头肿瘤切除术在儿童胰头肿瘤治疗中的应用. 浙江医学, 2019, 41(18): 1989-1991, 前插 5.
22. Beger HG, Nakao A, Mayer B, <italic>et al</italic>. Duodenum-preserving total and partial pancreatic head resection for benign tumors–systematic review and meta-analysis. Pancreatology, 2015, 15(2): 167-178.
23. 孙永辉, 张晓晶, 林海, 等. 保留十二指肠的胰头切除术与胰十二指肠切除术治疗慢性胰腺炎疗效的 Meta 分析. 中华内分泌外科杂志, 2019, 13(3): 249-255.
24. Zhao X, Cui N, Wang X, <italic>et al</italic>. Surgical strategies in the treatment of chronic pancreatitis: an updated systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore), 2017, 96(9): e6220.
25. 李建国, 王渊全, 陈谭根, 等. 保留十二指肠和胆管的胰头全切除术. 中华消化外科杂志, 2014, 13(11): 898-901.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Clinical analysis of long-term effect of duodenum-preserving pancreatic head resection versus pancreaticoduodenectomy: a single center experience

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content