Database research part <b>Ⅷ</b>: postoperative risks and complications of colorectal cancer_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

WANG Xiaodong ¹ , MENG Xinyu ^1,2 , LIU Jianbo ^1,2 ,  LI Li ¹

1. Department of Gastrointestinal Surgery, West China Hospital of Sichuan University, Chengdu 610041, P. R. China;
2. West China School of Medicine, Sichuan University, Chengdu 610041, P. R. China;

Corresponding author：

LI Li, Email: drlili116@126.com

Keywords：

colorectal cancer; database; big data; postoperative complication; medical quality

DOI：

10.7507/1007-9424.202101025

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To analyze the risks and complications after operation of colorectal cancer in the current version of Database from Colorectal Cancer (DACCA).Methods The DACCA version selected for this data analysis was the updated version on July 28th, 2020. The data items included surgery reaction, body temperature, flatus, pain and mental status; preoperative complication, postoperative complication, short-term and long-term complication. The selected data items were statistically analyzed.Results The total number of medical records (data rows) that met the criteria was 6 422, including 4 185 (65.2%) valid data on surgery reaction, 3 833 (59.7%) valid data on body temperature, 3 835 (59.7%) valid data on flatus, 3 597 (56.0%) valid data on pain, 3 551 (55.3%) valid data on mental status, 6 422 (100%) valid data on preoperative complications, postoperative complications, short-term complications and long-term complications. In the surgical response, 1 517 (36.2%) lines of data showed “normal” structure were the most. Among the days with elevated body temperature, the number of 0-day data lines with the structure of “body temperature >37.5 ℃” was the highest, with 1 980 (51.7%). In postoperative flatus, there were 1 675 (43.7%) data lines with the structure showing “3 days”. The largest number of rows (2 755, 76.6%) showed a structure that was “not obvious” in the pain scale. The mental status showed the highest number of “better” rows (2 976, 83.8%). There were 50 preoperative complications (0.8%). And 595 postoperative complications (9.3%), including anastomotic leakage (80, 13.4%), inflammatory ileus (62, 10.4%), pulmonary infection (57, 9.6%), and anastomotic bleeding (56, 9.4%), etc. There were 6 169 (96.1%) without short-term complication in structural form. There were 6 283 (97.8%) without long-term complications.Conclusions The changes in complications shown in the real world data from DACCA suggest that the focus of postoperative risks must be changed with the over the follow-up time. As for the complication evaluation system, it is necessary to establish a complete evaluation system combining the corresponding types and risks, to carry out valuable complication researches.

Citation： WANG Xiaodong, MENG Xinyu, LIU Jianbo, LI Li. Database research part Ⅷ: postoperative risks and complications of colorectal cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2021, 28(3): 369-375. doi: 10.7507/1007-9424.202101025 Copy

1.	汪晓东, 李立. 真实场景与大数据下的整体微创理念, 大幅提高结直肠癌远期生存率. 中国普外基础与临床杂志, 2019, 26(1): 92-95.
2.	汪晓东, 李希, 何欣林, 等. 数据库研究第一部分: 区域性医疗中心的结直肠癌与人群特征. 中国普外基础与临床杂志, 2019, 26(2): 212-220.
3.	Cavallaro P, Bordeianou L. Implementation of an ERAS pathway in colorectal surgery. Clin Colon Rectal Surg, 2019, 32(2): 102-108.
4.	Renz BW, Kasparek MS, Seeliger H, et al. The CR-POSSUM risk calculator predicts failure of enhanced recovery after colorectal surgery. Acta Chir Belg, 2015, 115(1): 20-26.
5.	冯金华, 黄明君, 胡艳杰, 等. 加速康复对结直肠癌患者术后炎性指标和免疫功能影响的研究进展. 重庆医学, 2015, 44(4): 548-551.
6.	Read TE, Brozovich M, Andujar JE, et al. Bowel sounds are not associated with flatus, bowel movement, or tolerance of oral intake in patients after major abdominal surgery. Dis Colon Rectum, 2017, 60(6): 608-613.
7.	Hawker GA, Mian S, Kendzerska T, et al. Measures of adult pain: visual analog scale for pain (VAS pain), numeric rating scale for pain (NRS pain), McGill pain questionnaire (MPQ), short-form McGill pain questionnaire (SF-MPQ), chronic pain grade scale (CPGS), short form-36 bodily pain scale (SF-36 BPS), and measure of intermittent and constant osteoarthritis pain (ICOAP). Arthritis Care Res (Hoboken), 2011, 63 Suppl 11: S240-S252.
8.	陈凛, 陈亚进, 董海龙, 等. 加速康复外科中国专家共识及路径管理指南(2018 版). 中国实用外科杂志, 2018, 38(1): 1-20.
9.	Lovich-Sapola J, Smith CE, Brandt CP. Postoperative pain control. Surg Clin North Am, 2015, 95(2): 301-318.
10.	Bolliger M, Kroehnert JA, Molineus F, et al. Experiences with the standardized classification of surgical complications (Clavien-Dindo) in general surgery patients. Eur Surg, 2018, 50(6): 256-261.
11.	de la Portilla F, Builes S, García-Novoa A, et al. Analysis of quality indicators for Colorectal Cancer Surgery in Units Accredited by the Spanish Association of Coloproctology. Cir Esp, 2018, 96(4): 226-233.
12.	Sparreboom CL, van Groningen JT, Lingsma HF, et al. Different risk factors for early and late colorectal anastomotic leakage in a nationwide audit. Dis Colon Rectum, 2018, 61(11): 1258-1266.
13.	颜登国, 张汝一, 甄运寰, 等. 结直肠癌切除术后吻合口瘘的治疗. 中华胃肠外科杂志, 2006, 9(5): 408.
14.	柯海林, 池畔, 林惠铭, 等. 直肠癌术后吻合口瘘对长期预后的影响. 中华胃肠外科杂志, 2015, 18(9): 920-924.
15.	郑晖, 池畔, 林惠铭, 等. 结直肠癌术后手术部位切口感染的预后因素分析. 中华外科杂志, 2016, 54(6): 424-428.
16.	任立焕, 傅卫, 王亮, 等. 结直肠癌患者围手术期并发症和病死率的研究. 中华普通外科杂志, 2007, 22(1): 3-7.
17.	Artinyan A, Orcutt ST, Anaya DA, et al. Infectious postoperative complications decrease long-term survival in patients undergoing curative surgery for colorectal cancer: a study of 12, 075 patients. Ann Surg, 2015, 261(3): 497-505.
18.	汪晓东, 方智, 李姣, 等. POSSUM 评分系统在外科手术中的应用现状. 重庆医学, 2008, 37(15): 1747-1749.

1. 汪晓东, 李立. 真实场景与大数据下的整体微创理念, 大幅提高结直肠癌远期生存率. 中国普外基础与临床杂志, 2019, 26(1): 92-95.
2. 汪晓东, 李希, 何欣林, 等. 数据库研究第一部分: 区域性医疗中心的结直肠癌与人群特征. 中国普外基础与临床杂志, 2019, 26(2): 212-220.
3. Cavallaro P, Bordeianou L. Implementation of an ERAS pathway in colorectal surgery. Clin Colon Rectal Surg, 2019, 32(2): 102-108.
4. Renz BW, Kasparek MS, Seeliger H, et al. The CR-POSSUM risk calculator predicts failure of enhanced recovery after colorectal surgery. Acta Chir Belg, 2015, 115(1): 20-26.
5. 冯金华, 黄明君, 胡艳杰, 等. 加速康复对结直肠癌患者术后炎性指标和免疫功能影响的研究进展. 重庆医学, 2015, 44(4): 548-551.
6. Read TE, Brozovich M, Andujar JE, et al. Bowel sounds are not associated with flatus, bowel movement, or tolerance of oral intake in patients after major abdominal surgery. Dis Colon Rectum, 2017, 60(6): 608-613.
7. Hawker GA, Mian S, Kendzerska T, et al. Measures of adult pain: visual analog scale for pain (VAS pain), numeric rating scale for pain (NRS pain), McGill pain questionnaire (MPQ), short-form McGill pain questionnaire (SF-MPQ), chronic pain grade scale (CPGS), short form-36 bodily pain scale (SF-36 BPS), and measure of intermittent and constant osteoarthritis pain (ICOAP). Arthritis Care Res (Hoboken), 2011, 63 Suppl 11: S240-S252.
8. 陈凛, 陈亚进, 董海龙, 等. 加速康复外科中国专家共识及路径管理指南(2018 版). 中国实用外科杂志, 2018, 38(1): 1-20.
9. Lovich-Sapola J, Smith CE, Brandt CP. Postoperative pain control. Surg Clin North Am, 2015, 95(2): 301-318.
10. Bolliger M, Kroehnert JA, Molineus F, et al. Experiences with the standardized classification of surgical complications (Clavien-Dindo) in general surgery patients. Eur Surg, 2018, 50(6): 256-261.
11. de la Portilla F, Builes S, García-Novoa A, et al. Analysis of quality indicators for Colorectal Cancer Surgery in Units Accredited by the Spanish Association of Coloproctology. Cir Esp, 2018, 96(4): 226-233.
12. Sparreboom CL, van Groningen JT, Lingsma HF, et al. Different risk factors for early and late colorectal anastomotic leakage in a nationwide audit. Dis Colon Rectum, 2018, 61(11): 1258-1266.
13. 颜登国, 张汝一, 甄运寰, 等. 结直肠癌切除术后吻合口瘘的治疗. 中华胃肠外科杂志, 2006, 9(5): 408.
14. 柯海林, 池畔, 林惠铭, 等. 直肠癌术后吻合口瘘对长期预后的影响. 中华胃肠外科杂志, 2015, 18(9): 920-924.
15. 郑晖, 池畔, 林惠铭, 等. 结直肠癌术后手术部位切口感染的预后因素分析. 中华外科杂志, 2016, 54(6): 424-428.
16. 任立焕, 傅卫, 王亮, 等. 结直肠癌患者围手术期并发症和病死率的研究. 中华普通外科杂志, 2007, 22(1): 3-7.
17. Artinyan A, Orcutt ST, Anaya DA, et al. Infectious postoperative complications decrease long-term survival in patients undergoing curative surgery for colorectal cancer: a study of 12, 075 patients. Ann Surg, 2015, 261(3): 497-505.
18. 汪晓东, 方智, 李姣, 等. POSSUM 评分系统在外科手术中的应用现状. 重庆医学, 2008, 37(15): 1747-1749.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Database research part Ⅷ: postoperative risks and complications of colorectal cancer

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content