Part <b>Ⅸ</b> of database building: tag and structure of the neoadjuvant therapy of colorectal cancer_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

WANG Xiaodong ¹ , YOU Yixian ^1,2 , Yu Qi’ao ^1,2 ,  LI Li ¹

1. Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, P.R.China;
2. West China School of Medicine/West China Hospital of Sichuan University, Chengdu 610041, P.R.China;

Corresponding author：

LI Li, Email: drlili116@126.com

Keywords：

colorectal neoplasm; database; big data; neoadjuvant therapy

DOI：

10.7507/1007-9424.202104011

Video：

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Objective To describe the constructive process of neoadjuvant therapy for colorectal cancer part in the West China Colorectal Cancer Database (DACCA).Method We used the form of text description.Results The specific concept of neoadjuvant therapy for colorectal cancer including neoadjuvant treatment therapies, compliance of patients with neoadjuvant therapy, neoadjuvant therapy intensity scheme, the CEA value of patients during neoadjuvant therapy, changes of symptoms, changes of primary tumor size in colorectal cancer, and TRG grading of the DACCA in the West China Hospital were defined. Then the neoadjuvant therapies were detailed for their definition, label, structure, error correction, and update.Conclusion Through detailed description and specification of neoadjuvant therapy for colorectal cancer in DACCA in West China Hospital, it can provide a reference for the standardized treatment of colorectal cancer and also provide experiences for the peers who wish to build a colorectal cancer database.

Citation： WANG Xiaodong, YOU Yixian, Yu Qi’ao, LI Li. Part Ⅸ of database building: tag and structure of the neoadjuvant therapy of colorectal cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2021, 28(6): 799-804. doi: 10.7507/1007-9424.202104011 Copy

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9.	National Comprehensive Cancer Network. (NCCN) Clinical Practice Guidelines in Oncology. Rectal Cancer, Version 1.2021. https://www.nccn.org/guidelines/category_1.
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11.	Trilisky I, Wroblewski K, Vannier MW, et al. CT colonography with computer-aided detection: recognizing the causes of false-positive reader results. Radiographics, 2014, 34(7): 1885-1905.
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1. 汪晓东, 李立. 数据库建设第一部分: 个人数据的标签与结构化. 中国普外基础与临床杂志, 2019, 26(3): 335-342.
2. 汪晓东, 李立. 真实场景与大数据下的整体微创理念, 大幅提高结直肠癌远期生存率. 中国普外基础与临床杂志, 2019, 26(1): 92-95 .
3. Trimble EL, Ungerleider RS, Abrams JA, et al. Neoadjuvant therapy in cancer treatment. Cancer, 1993, 72(11 Suppl): 3515-3524 .
4. Feeney G, Sehgal R, Sheehan M, et al. Neoadjuvant radiotherapy for rectal cancer management. World J Gastroenterol, 2019, 25(33): 4850-4869.
5. Dossa F, Chesney TR, Acuna SA, et al. A watch-and-wait approach for locally advanced rectal cancer after a clinical complete response following neoadjuvant chemoradiation: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol, 2017, 2(7): 501-513.
6. 中华人民共和国国家卫生健康委员会. 中国结直肠癌诊疗规范(2020年版). 中华外科杂志, 2020, 58(8): 561-585.
7. Simon K. Colorectal cancer development and advances in screening. Clin Interv Aging, 2016, 11: 967-976.
8. Horvat N, Carlos Tavares Rocha C, Clemente Oliveira B, et al. MRI of rectal cancer: tumor staging, imaging techniques, and management. Radiographics, 2019, 39(2): 367-387.
9. National Comprehensive Cancer Network. (NCCN) Clinical Practice Guidelines in Oncology. Rectal Cancer, Version 1.2021. https://www.nccn.org/guidelines/category_1.
10. Nie K, Shi L, Chen Q, et al. Rectal cancer: assessment of neoadjuvant chemoradiation outcome based on radiomics of multiparametric MRI. Clin Cancer Res, 2016, 22(21): 5256-5264.
11. Trilisky I, Wroblewski K, Vannier MW, et al. CT colonography with computer-aided detection: recognizing the causes of false-positive reader results. Radiographics, 2014, 34(7): 1885-1905.
12. Hosny A, Parmar C, Quackenbush J, et al. Artificial intelligence in radiology. Nat Rev Cancer, 2018, 18(8): 500-510.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Part Ⅸ of database building: tag and structure of the neoadjuvant therapy of colorectal cancer

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