自噬相关分子机制在肺癌中的作用_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

孙雨晴 ,  韩锋锋

Corresponding author：

韩锋锋, Email: fengfh86@sina.com

Keywords：

DOI：

10.7507/1671-6205.201704023

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Citation： 孙雨晴, 韩锋锋. 自噬相关分子机制在肺癌中的作用. Chinese Journal of Respiratory and Critical Care Medicine, 2018, 17(3): 319-322. doi: 10.7507/1671-6205.201704023 Copy

1.	An HK, Kim KS, Lee JW, et al. Mimulone-induced autophagy through p53-mediated AMPK/mTOR pathway increases caspase-mediated apoptotic cell death in a549 human lung cancer cells. PLoS ONE, 2014, 9(12): e114607.
2.	Wu S, Su J, Qian H, Guo T. SLC27A4 regulate ATG4B activity and control reactions to chemotherapeutics-induced autophagy in human lung cancer cells. Tumour Biol, 2016, 37(5): 6943-6952.
3.	Rebecca VW, Amaravadi RK. Emerging strategies to effectively target autophagy in cancer. Oncogene, 2016, 35(1): 1-11.
4.	Galluzzi L, Pietrocola F, Bravo-San Pedro JM, et al. Autophagy in malignant transformation and cancer progression. EMBO J, 2015, 34(7): 856-880.
5.	White E, Mehnert JM, Chan CS. Autophagy, metabolism, and cancer. Clin Cancer Res, 2015, 21(22): 5037-5046.
6.	Sharma K, Le N, Alotaibi M, et al. Cytotoxic autophagy in cancer therapy. Int J Mol Sci, 2014, 15(6): 10034-10051.
7.	Eileen White, Cristina Karp, Anne M-S, et al. Role of autophagy in suppression of inflammation and cancer. Curr Opin Cell Biol, 2010, 22(2): 212-217.
8.	Liu JL, Chang KC, Lo CC, et al. Expression of autophagy-related protein Beclin-1 in malignant canine mammary tumors. BMC Vet Res, 2013, 9: 75.
9.	Schläfli AM, Adams O, Galván JA, et al. Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. Oncotarget, 2016, 7(26): 39544-39555.
10.	Wang XF, Du ZY, Li LY, et al. Beclin 1 and p62 expression in non-small cell lung cancer: relation with malignant behaviors and clinical outcome. Int J Clin Exp Pathol, 2015, 8(9): 10644-10652.
11.	Caiola E, Brunelli L, Marabese M, et al. Different metabolic responses to PI3K inhibition in NSCLC cells harboring wild-type and G12C mutant KRAS. Oncotarget, 2016, 7(32): 51462-51472.
12.	Van Nostrand JL, Brisac A, Mello SS, et al. The p53 target gene SIVA enables non-small cell lung cancer development. Cancer Discov, 2015, 5(6): 622-635.
13.	Dong QZ, Wang Y, Tang ZP, et al. Derlin-1 is overexpressed in Non-small cell lung cancer and promotes cancer cell invasion via EGFR-ERK-mediated up-regulation of MMP-2 and MMP-9. Am J Pathol, 2013, 182(3): 954-964.
14.	Ran Y, Hu H, Hu D, et al. Derlin-1 is overexpressed on the tumor cell surface and enables antibody-mediated tumor targeting therapy. Clin Cancer Res, 2008, 14(20): 6538-6545.
15.	Xu L, Wang ZH, Xu D, ……Wan T, Guo SL, et al. Expression of Derlin-1 and its effect on expression of autophagy marker genes under endoplasmic reticulum stress in lung cancer cells. Cancer Cell Int, 2014, 14: 50.
16.	Lee JG, Shin JH, Shim HS, et al. Autophagy contributes to the chemo-resistance of non-small cell lung cancer in hypoxic conditions. Respir Res, 2015, 16: 138.
17.	Chen TJ, Ren H, Thakur A, et al. Decreased level of klotho contributes to drug resistance in lung cancer cells: involving in klotho-mediated cell autophagy. DNA Cell Biol, 2016, 35(12): 751-757.
18.	Lin XC, Liao Y, Chen X, et al. Regulation of oncoprotein 18/Stathmin signaling by ERK concerns the resistance to taxol in nonsmall cell lung cancer cells. Cancer Biother Radiopharm, 2016, 31(2): 37-43.
19.	Nie W, Xu MD, Gan L, et al. Overexpression of stathmin 1 is a poor prognostic biomarker in non-small cell lung cancer. Lab Invest, 2015, 95(1): 56-64.
20.	Zhang X, Ji JF, Yang Y, et al. Stathmin1 increases radioresistance by enhancing autophagy in non-small-cell lung cancer cells. Onco Targets Ther, 2016, 9: 2565-2574.
21.	Smejkal K, Grycová L, Marek R, et al. C-geranyl compounds from Paulownia tomentosa fruits. J Nat Prod, 2007, 70(8): 1244-1248.
22.	Chakradeo S, Sharma K, Alhaddad A, et al. Yet another function of p53--the switch that determines whether radiation-induced autophagy will be cytoprotective or nonprotective: implications for autophagy inhibition as a therapeutic strategy. Mol Pharmacol, 2015, 87(5): 803-814.
23.	Chatterjee A, Chattopadhyay D, Chakrabarti G. miR-17-5p downregulation contributes to paclitaxel resistance of lung cancer cells through altering beclin1 expression. PLoS ONE, 2014, 9(4): e95716.
24.	Guo JY, White E. Autophagy, metabolism, and cancer. Cold Spring Harb Symp Quant Biol, 2017: 030981. [Epub ahead of print]. Available at: http://symposium.cshlp.org/content/early/2017/02/16/sqb.2016.81.030981.full.pdf.
25.	Feng Y, He D, Yao Z, Klionsky DJ. The machinery of macro-autophagy. Cell Res, 2014; 24: 24-41.
26.	García-Cano J, Ambroise G, Pascual-Serra R, et al. Exploiting the potential of autophagy in cisplatin therapy: a new strategy to overcome resistance. Oncotarget, 2015, 6(17): 15551-15565.

1. An HK, Kim KS, Lee JW, et al. Mimulone-induced autophagy through p53-mediated AMPK/mTOR pathway increases caspase-mediated apoptotic cell death in a549 human lung cancer cells. PLoS ONE, 2014, 9(12): e114607.
2. Wu S, Su J, Qian H, Guo T. SLC27A4 regulate ATG4B activity and control reactions to chemotherapeutics-induced autophagy in human lung cancer cells. Tumour Biol, 2016, 37(5): 6943-6952.
3. Rebecca VW, Amaravadi RK. Emerging strategies to effectively target autophagy in cancer. Oncogene, 2016, 35(1): 1-11.
4. Galluzzi L, Pietrocola F, Bravo-San Pedro JM, et al. Autophagy in malignant transformation and cancer progression. EMBO J, 2015, 34(7): 856-880.
5. White E, Mehnert JM, Chan CS. Autophagy, metabolism, and cancer. Clin Cancer Res, 2015, 21(22): 5037-5046.
6. Sharma K, Le N, Alotaibi M, et al. Cytotoxic autophagy in cancer therapy. Int J Mol Sci, 2014, 15(6): 10034-10051.
7. Eileen White, Cristina Karp, Anne M-S, et al. Role of autophagy in suppression of inflammation and cancer. Curr Opin Cell Biol, 2010, 22(2): 212-217.
8. Liu JL, Chang KC, Lo CC, et al. Expression of autophagy-related protein Beclin-1 in malignant canine mammary tumors. BMC Vet Res, 2013, 9: 75.
9. Schläfli AM, Adams O, Galván JA, et al. Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. Oncotarget, 2016, 7(26): 39544-39555.
10. Wang XF, Du ZY, Li LY, et al. Beclin 1 and p62 expression in non-small cell lung cancer: relation with malignant behaviors and clinical outcome. Int J Clin Exp Pathol, 2015, 8(9): 10644-10652.
11. Caiola E, Brunelli L, Marabese M, et al. Different metabolic responses to PI3K inhibition in NSCLC cells harboring wild-type and G12C mutant KRAS. Oncotarget, 2016, 7(32): 51462-51472.
12. Van Nostrand JL, Brisac A, Mello SS, et al. The p53 target gene SIVA enables non-small cell lung cancer development. Cancer Discov, 2015, 5(6): 622-635.
13. Dong QZ, Wang Y, Tang ZP, et al. Derlin-1 is overexpressed in Non-small cell lung cancer and promotes cancer cell invasion via EGFR-ERK-mediated up-regulation of MMP-2 and MMP-9. Am J Pathol, 2013, 182(3): 954-964.
14. Ran Y, Hu H, Hu D, et al. Derlin-1 is overexpressed on the tumor cell surface and enables antibody-mediated tumor targeting therapy. Clin Cancer Res, 2008, 14(20): 6538-6545.
15. Xu L, Wang ZH, Xu D, ……Wan T, Guo SL, et al. Expression of Derlin-1 and its effect on expression of autophagy marker genes under endoplasmic reticulum stress in lung cancer cells. Cancer Cell Int, 2014, 14: 50.
16. Lee JG, Shin JH, Shim HS, et al. Autophagy contributes to the chemo-resistance of non-small cell lung cancer in hypoxic conditions. Respir Res, 2015, 16: 138.
17. Chen TJ, Ren H, Thakur A, et al. Decreased level of klotho contributes to drug resistance in lung cancer cells: involving in klotho-mediated cell autophagy. DNA Cell Biol, 2016, 35(12): 751-757.
18. Lin XC, Liao Y, Chen X, et al. Regulation of oncoprotein 18/Stathmin signaling by ERK concerns the resistance to taxol in nonsmall cell lung cancer cells. Cancer Biother Radiopharm, 2016, 31(2): 37-43.
19. Nie W, Xu MD, Gan L, et al. Overexpression of stathmin 1 is a poor prognostic biomarker in non-small cell lung cancer. Lab Invest, 2015, 95(1): 56-64.
20. Zhang X, Ji JF, Yang Y, et al. Stathmin1 increases radioresistance by enhancing autophagy in non-small-cell lung cancer cells. Onco Targets Ther, 2016, 9: 2565-2574.
21. Smejkal K, Grycová L, Marek R, et al. C-geranyl compounds from Paulownia tomentosa fruits. J Nat Prod, 2007, 70(8): 1244-1248.
22. Chakradeo S, Sharma K, Alhaddad A, et al. Yet another function of p53--the switch that determines whether radiation-induced autophagy will be cytoprotective or nonprotective: implications for autophagy inhibition as a therapeutic strategy. Mol Pharmacol, 2015, 87(5): 803-814.
23. Chatterjee A, Chattopadhyay D, Chakrabarti G. miR-17-5p downregulation contributes to paclitaxel resistance of lung cancer cells through altering beclin1 expression. PLoS ONE, 2014, 9(4): e95716.
24. Guo JY, White E. Autophagy, metabolism, and cancer. Cold Spring Harb Symp Quant Biol, 2017: 030981. [Epub ahead of print]. Available at: http://symposium.cshlp.org/content/early/2017/02/16/sqb.2016.81.030981.full.pdf.
25. Feng Y, He D, Yao Z, Klionsky DJ. The machinery of macro-autophagy. Cell Res, 2014; 24: 24-41.
26. García-Cano J, Ambroise G, Pascual-Serra R, et al. Exploiting the potential of autophagy in cisplatin therapy: a new strategy to overcome resistance. Oncotarget, 2015, 6(17): 15551-15565.

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Chinese Journal of Respiratory and Critical Care Medicine

自噬相关分子机制在肺癌中的作用

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