Effectiveness of External Application with JinHuang Powder for Diabetic Foot Ulcers: A Systematic Review_Chinese Journal of Evidence-Based Medicine

Authors：

 MALi ¹ , TIANXu ¹ , YILi-juan ¹ ,  WANGYan ²

1. Graduate College, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;
2. School of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;

Corresponding author：

WANGYan, Email: yan2015wangly@163.com

Keywords：

JinHuang powder; Diabetic foot ulcer; Systematic review; Meta-analysis; Randomized controlled trial

DOI：

10.7507/1672-2531.20150096

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To systematically evaluate the potential effectiveness of JinHuang powder in the treatment of diabetic foot ulcers (DFUs). Methods Databases including PubMed, The Cochrane Library, Web of Science, CBM, WanFang data, VIP and CNKI were electronically searched from their inception to December 2013, to identify randomized controlled trials (RCTs) about JinHuang powder for DFUs. Two reviewers screened literature according to the inclusion and exclusion criteria, extracted data and assessed the methodological quality of included studies, and then meta-analysis was performed by using RevMan 5.1 software. Results A total of 3 RCTs involving 198 patients were included. The results of meta-analysis showed that:the JinHuang powder group were superior to the control group in total effective rate (RR=1.25, 95%CI 1.10 to 1.41, P=0.00) and the wound healing time (SMD=-3.32, 95%CI -5.69 to -0.96, P=0.00). Conclusion Current evidence suggests that the JinHuang powder is an effective therapeutic method for DFUs. Because of the limitations of quantity and quality of the eligible studies, large sample size studies are needed to validate the conclusion.

Citation： MALi, TIANXu, YILi-juan, WANGYan. Effectiveness of External Application with JinHuang Powder for Diabetic Foot Ulcers: A Systematic Review. Chinese Journal of Evidence-Based Medicine, 2015, 15(5): 581-585. doi: 10.7507/1672-2531.20150096 Copy

1.	Peregrina-Barretoa H, Morales-Hernandezb LA, Rangel-Magdalenoa JJ, et al. Quantitative estimation of temperature variations in plantar angiosomes:a study case for diabetic foot. Computational and Mathematical Methods in Med, 2014:585306.
2.	李菊川. 糖尿病足溃疡诊疗研究新进展. 北方药学, 2014, 11(3):58-59.
3.	Marineau ML, Herrington MT, Swenor KM, et al. Maggot debridement therapy in the treatment of complex diabetic wounds. Hawaii Med J, 2011, 70(3):121-124.
4.	Yamamoto H, Watanabe L, Yamamoto, et al. RAGE in diabetic nephropathy. Curt Mol Med, 2007, 7(8):752-757.
5.	Brod M. Quality of life issues in patients with diabetes and lower extremity ulcers:patients and care givers. Quality life Res, 1998, 7(4):365-372.
6.	Ribu L, Wahl A. Living with diabetic foot ulcers, a life of fear, restrictions and pain. Ostomy Wound manage, 2004, 50(2):57-67.
7.	Levin ME. Management of the diabetic foot:preventing amputation. South med J, 2002, 95(1):10-20.
8.	盛路芳, 张美英, 吴红娟, 等. 金黄散加蜂蜜外敷治疗皮肤过敏的效果观察及护理. 现代临床护理, 2013, 12(10):47-49.
9.	Higgins JPT, Altman DG. Chapter 8:Assessing risk of bias in included studies. In:Higgins JPT, Green S (editors). Cochrane handbook for systematic reviews of interventions version 5.0.2 (updated September 2009). The Cochrane Collaboration, 2009.
10.	崔晓斌, 王英果, 罗振立. 局部清创换药联合金黄散外用治疗糖尿病足临床观察. 中国医药指南, 2011, 9(24):318-319.
11.	贾秀卿, 孙喜明. 如意金黄散外敷在糖尿病足溃疡护理中的应用. 临床和实验医学杂志, 2010, 9(10):786-787.
12.	马书田, 刘利珍. 如意金黄散外用联合局部清创治疗糖尿病足疗效观察. 现代中西医结合杂志, 2011, 20(7):828-829.
13.	李仕明. 糖尿病足检查方法及诊断标准(草案). 中国糖尿病杂志, 1996, 4(2):126.
14.	朱橲星. 现代糖尿病学. 上海:复旦大学出版社, 2002:157-182.
15.	周兆熊, 张柏根. 糖尿病足溃疡的诊断与治疗. 中国实用外科杂志, 2006, 26(2):97-98.
16.	Yang WY, Lu JM, Weng JP, et al. Prevalence of diabetes among men and women in China. N Engl J Med, 2010, 362(12):1090-1101.
17.	王玉珍, 许樟荣. 第五届国际血管外科暨第一届国际糖尿病血管疾病会议(糖尿病足部分)纪要. 中华糖尿病杂志, 2005, 13(5):152-153.
18.	Driver VR, Madsen J, Goodman RA. Reducing amputation rates in patients with diabetes at a military medical-center:the limb preservation service model. Diabetes Care, 2005, 28(2):248-253.
19.	罗炬兰. 中医护理在糖尿病足患者足部护理的临床应用. 护理研究, 2011, 18(6):120-121.
20.	陈龙云, 钟鹏飞. 糖尿病足的中医病因病机探讨. 中国医学创新, 2010, 7(26):179-181.
21.	张友杰.中西医结合治疗糖尿病足的疗效观察. 吉林医学, 2011, 32(23):4809-4810.
22.	柴政, 吕延伟. 糖尿病足的临床研究近况. 实用中医内科杂志, 2013, 27(1):155-157.
23.	Yi ZH. A meta analysis on expression of cyclooxygenase-2 in gastric carcinoma. Bulletin of Chinese Cancer, 2007, 16(5):365-367.
24.	王和鸣. 中医伤科学. 北京:中国中医药出版社, 2002:352.

1. Peregrina-Barretoa H, Morales-Hernandezb LA, Rangel-Magdalenoa JJ, et al. Quantitative estimation of temperature variations in plantar angiosomes:a study case for diabetic foot. Computational and Mathematical Methods in Med, 2014:585306.
2. 李菊川. 糖尿病足溃疡诊疗研究新进展. 北方药学, 2014, 11(3):58-59.
3. Marineau ML, Herrington MT, Swenor KM, et al. Maggot debridement therapy in the treatment of complex diabetic wounds. Hawaii Med J, 2011, 70(3):121-124.
4. Yamamoto H, Watanabe L, Yamamoto, et al. RAGE in diabetic nephropathy. Curt Mol Med, 2007, 7(8):752-757.
5. Brod M. Quality of life issues in patients with diabetes and lower extremity ulcers:patients and care givers. Quality life Res, 1998, 7(4):365-372.
6. Ribu L, Wahl A. Living with diabetic foot ulcers, a life of fear, restrictions and pain. Ostomy Wound manage, 2004, 50(2):57-67.
7. Levin ME. Management of the diabetic foot:preventing amputation. South med J, 2002, 95(1):10-20.
8. 盛路芳, 张美英, 吴红娟, 等. 金黄散加蜂蜜外敷治疗皮肤过敏的效果观察及护理. 现代临床护理, 2013, 12(10):47-49.
9. Higgins JPT, Altman DG. Chapter 8:Assessing risk of bias in included studies. In:Higgins JPT, Green S (editors). Cochrane handbook for systematic reviews of interventions version 5.0.2 (updated September 2009). The Cochrane Collaboration, 2009.
10. 崔晓斌, 王英果, 罗振立. 局部清创换药联合金黄散外用治疗糖尿病足临床观察. 中国医药指南, 2011, 9(24):318-319.
11. 贾秀卿, 孙喜明. 如意金黄散外敷在糖尿病足溃疡护理中的应用. 临床和实验医学杂志, 2010, 9(10):786-787.
12. 马书田, 刘利珍. 如意金黄散外用联合局部清创治疗糖尿病足疗效观察. 现代中西医结合杂志, 2011, 20(7):828-829.
13. 李仕明. 糖尿病足检查方法及诊断标准(草案). 中国糖尿病杂志, 1996, 4(2):126.
14. 朱橲星. 现代糖尿病学. 上海:复旦大学出版社, 2002:157-182.
15. 周兆熊, 张柏根. 糖尿病足溃疡的诊断与治疗. 中国实用外科杂志, 2006, 26(2):97-98.
16. Yang WY, Lu JM, Weng JP, et al. Prevalence of diabetes among men and women in China. N Engl J Med, 2010, 362(12):1090-1101.
17. 王玉珍, 许樟荣. 第五届国际血管外科暨第一届国际糖尿病血管疾病会议(糖尿病足部分)纪要. 中华糖尿病杂志, 2005, 13(5):152-153.
18. Driver VR, Madsen J, Goodman RA. Reducing amputation rates in patients with diabetes at a military medical-center:the limb preservation service model. Diabetes Care, 2005, 28(2):248-253.
19. 罗炬兰. 中医护理在糖尿病足患者足部护理的临床应用. 护理研究, 2011, 18(6):120-121.
20. 陈龙云, 钟鹏飞. 糖尿病足的中医病因病机探讨. 中国医学创新, 2010, 7(26):179-181.
21. 张友杰.中西医结合治疗糖尿病足的疗效观察. 吉林医学, 2011, 32(23):4809-4810.
22. 柴政, 吕延伟. 糖尿病足的临床研究近况. 实用中医内科杂志, 2013, 27(1):155-157.
23. Yi ZH. A meta analysis on expression of cyclooxygenase-2 in gastric carcinoma. Bulletin of Chinese Cancer, 2007, 16(5):365-367.
24. 王和鸣. 中医伤科学. 北京:中国中医药出版社, 2002:352.

Chinese Journal of Evidence-Based Medicine

Effectiveness of External Application with JinHuang Powder for Diabetic Foot Ulcers: A Systematic Review

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content