WANG Zhe 1,2,3 , WANG Ya 2,3 , LIU Yanfei 1 , LIU Yue 2,3 , LI Lizhi 2,3
  • 1. Graduate School of Beijing University of Chinese Medicine, Beijing, 100029, P.R.China;
  • 2. Center of Cardiovascular Diseases, XiYuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, P.R.China;
  • 3. National Clinical Research Center of Cardiovascular Diseases of Chinese Medicine, Beijing, 100091, P.R.China;
LIU Yue, Email: liuyue@188.com; LI Lizhi, Email: lilizhi0723@126.com
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Objective To overview the systematic reviews (SRs) on the efficacy of traditional Chinese medicine (TCM) in the treatment of atrial fibrillation.Methods PubMed, The Cochrane Library, EMbase, CNKI, CBM, WanFang Data and VIP database were electronically searched to collect SRs of TCM in the treatment of atrial fibrillation from inception to July 2019. Two researchers independently screened literature, extracted data and then the methodological quality, reporting quality and evidence quality of the included documents were evaluated by AMSTAR2 tool, PRISMA statement and GRADE method.Results A total of 20 SRs were included. In which, 15 SRs evaluated clinical efficacy and 12 SRs analyzed adverse reactions. The methodological quality evaluation by AMSTAR2 was generally low and none of them being high quality, 1 of them being low quality and 19 of them being extremely low quality. The items with poor scores were item 2, 7, 8, 9, 10, 12, 13, 14 and 16. The PRISMA score ranged from 14 to 22.5. The quality question of the report was mainly manifested in the aspects of scheme and registration, data item, other analysis methods and sources of fundings. Evidence quality evaluation of GRADE outcome indicators was generally low.Conclusion Traditional Chinese medicine for atrial fibrillation can improve clinical efficacy and reduce adverse reactions. The overall methodological quality of the included literature is not high, and the quality of evidence is generally low. It suggest that further high-quality clinical studies should be carried out to provide a basis for evaluating the clinical efficacy of traditional Chinese medicine in treatment of atrial fibrillation.

Citation: WANG Zhe, WANG Ya, LIU Yanfei, LIU Yue, LI Lizhi. Traditional Chinese medicine treatment for atrial fibrillation: an overview of systematic reviews. Chinese Journal of Evidence-Based Medicine, 2020, 20(2): 199-206. doi: 10.7507/1672-2531.201908110 Copy

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