细胞程序化死亡在癫痫发生过程中的机制研究_Journal of Epilepsy

Authors：

高振 ¹ ,  翁柠 ^1,2

1. ;
2. ;

Corresponding author：

翁柠, Email: 16138649@qq.com

Keywords：

癫痫; 细胞自噬; 细胞凋亡; 程序性坏死; 细胞焦亡

DOI：

10.7507/2096-0247.20210026

Video：

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癫痫是一种病因复杂且发病机制尚未明确的慢性神经系统疾病。目前，国内外对癫痫开展了大量的研究。其中有研究认为，癫痫发生后，大脑海马区出现了一些结构性的改变，这些改变就包括细胞程序化死亡。细胞程序化死亡的方式主要有四种，分别是细胞自噬、细胞凋亡、程序性坏死和细胞焦亡，这四种死亡方式有着各自的特点和相应的机制。文章就细胞程序化死亡在癫痫发生过程中的相关机制作一综述，探讨癫痫发生分别与细胞自噬、细胞凋亡、程序性坏死和细胞焦亡的关系。

Citation： 高振, 翁柠. 细胞程序化死亡在癫痫发生过程中的机制研究. Journal of Epilepsy, 2021, 7(2): 152-158. doi: 10.7507/2096-0247.20210026 Copy

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