Objective To explore the effect of endovascular treatment guided by ultrasonography combined with portosystemic shunts on the patients with Budd-Chiari Syndrome (BCS).
Methods The clinical data of 136 patients with BCS treated by balloon angioplasty and stent implantation guided by Doppler ultrasonography in our hospital from January 1995 to January 2011 were retrospectively analyzed.After balloon angioplasty,53 patients were treated by inferior vena cava (IVC) stent implantation and 31 patients with hepatic venous occlusion underwent portosystemic shunts (PSSs) at one week after endovascular treatment.The long-and short-term effects after treatment were studied.
Results After endovascular procedures,the IVC pressure of patients significantly decreased (P<0.01),while IVC diameter, flow velocity in the lesion,and right atrial pressure of patients showed significant increase(P<0.01).Slight heart dysfunction appeared in 13 cases of patients.After shunting,acute pancreatitis occurred in 3 cases, and 1 patient died of upper gastrointestinal hemorrhage on the 10 d after PSSs.Doppler ultrasonography for IVC and shunt vessels showed:the swollen liver and spleen lessened on 3d after endovascular procedures.The swollen liver lessened 2-7cm (mean 5.5cm),swollen spleen lessened 3-8cm (mean 5.8cm), and the time of ascites disappearance was 3-60d (mean 14d).All the patients were followed up for 1 month to 15 years with an average of 3 years.Restenosis of the distal part of stent was found in 1 patient in 2 years after operation, hepatic vein occlusion occurred in 1 case in 1 year after treatment,hepatocellular carcinoma occurred in 1 patient in 3 years after stent implantation,and 1 patient died of C type hepatitis after 1 year,and 5 out of 6 cases of patients with infertility had babies after 1 year.All patients had no stent migration or occlusion of shunts and the symptoms of portal hypertension were obviously relieved.
Conclusions Endovascular treatment guided by Doppler ultrasonography is a convenient,safe,and effective method for BCS.Portosystemic shunts are commended to patients with hepatic venous occlusions.The above mentioned methods provide a feasible and effective means for IVC stenosis and short segment occlusion with hepatic vein occlusion of BCS.
Citation:
HAN Bing,HUANG Yingjun,ZHANG Hongguang,ZHOU Chenguang,JI Guohui,YANG Zheng,ZHANG Liang.. Study on The Effect of Endovascular Treatment Guided by Ultrasonography Combined with Portosystemic Shunts for Budd-Chiari Syndrome. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2012, 19(1): 72-76. doi:
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Kew MC, Hodkinson HJ. Membranous obstruction of the inferior vena cava and its causal relation to hepatocellular carcinoma [J].Liver Int, 2006, 26(1): 1-7..
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赵文星, 李秀丽, 杨书环.介入治疗布-加综合征远期疗效观察 [J].中国现代医生, 2008, 46(14): 65-66..
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王茂华, 金星.布-加综合征的介入与手术治疗 [J].中国普通外科杂志, 2008, 17(6): 602-604..
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张小明, 李清乐.布加综合征诊治现状 [J].中国医学科学院学报, 2007, 29(1): 25-28..
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李春民, 卞策, 汪忠镐.布-加综合征的个体化手术治疗 [J].中国普外基础与临床杂志2012 年1 月第19 卷第1 期 Chin J Bases ? 76 ? Clin General Surg, Vol. 19, No. 1, Jan. 2012中国普外基础与临床杂志, 2010, 17(12): 1306-1307..
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李震, 汪忠镐, 霍小森, 等.腹水静脉回输在重症布加综合征治疗中的作用 [J].中国普外基础与临床杂志, 2010,17(8):828-831, 836..
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李晓强, 余朝文, 吴允明.下腔静脉及肝静脉短段病变型布-加综合征的外科治疗 [J].中华普通外科杂志, 2001, 16(5):23-25..
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汪忠镐, 马颂章, 王仕华, 等.布-加综合征根治性矫正术式的探讨: 附37 例报告 [J].中华胸心血管外科杂志, 1995,11(3): 132-134..
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余军, 汪忠镐.下腔静脉内球囊成形支架置放加肠腔分流术治疗布-加综合征 [J].普外临床, 1995, 10(5): 307-308..
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陈学明, 汪忠镐, 尹振明, 等.布-加综合征452 例术后并发症的处理 [J].中华普通外科杂志, 1999, 14(6): 417-420..
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魏志新.肠腔分流或联合下腔静脉内支架置入术治疗布-加综合征 [J].中国普外基础与临床杂志, 2001, 8(4): 265-266..
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李晓东, 陈学明, 汪忠镐, 等.肝外型门静脉高压症外科治疗42 例经验 [J]. 中国普外基础与临床杂志, 2002, 9(2): 122-123.
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李震, 贾如冰, 汪忠镐, 等.附脐静脉在门静脉高压分流术中的应用 [J].中国普外基础与临床杂志, 2010, 17(2): 180-181.
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侯钰, 孙广新, 杨俊山.门静脉高压时脐静脉或附脐静脉的血流动力学改变及临床意义 [J].肝胆外科杂志, 2004, 12(5):332-334..
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王欣博, 童中勋, 刘威, 等. 门静脉海绵样变性外科治疗的研究进展 [J]. 中国普外基础与临床杂志, 2008, 15(12):877-879.
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王曙光, 蔡景修, 刘子沛, 等.脐静脉桥式选择性分流术 [J].消化外科杂志, 2003, 2(4): 239-242..
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李震, 汪忠镐, 卞策, 等. 肠房转流通畅前提下并发顽固性腹水的治疗 [J]. 中国普外基础与临床杂志, 2009, 16(7):571-572..
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汪忠镐, 李震.我国血管外科的现状和发展 [J].中国普外基础与临床杂志, 2006, 13(6): 625-628.
|
- 1. Xu PQ, Ma XX, Ye XX, et al.Surgical treatment of 1 360 cases of Budd-chiari syndrome:20-year experience [J].Hepatobiliary Pancreat Dis Int, 2004, 3(3): 391-394..
- 2. Kew MC, Hodkinson HJ. Membranous obstruction of the inferior vena cava and its causal relation to hepatocellular carcinoma [J].Liver Int, 2006, 26(1): 1-7..
- 3. 舒畅, 罗明尧, 姜晓华, 等.介入和外科手术治疗布加综合征39 例诊治体会 [J].中国现代手术学杂志, 2011, 15(1):47-5.
- 4. 赵文星, 李秀丽, 杨书环.介入治疗布-加综合征远期疗效观察 [J].中国现代医生, 2008, 46(14): 65-66..
- 5. 王茂华, 金星.布-加综合征的介入与手术治疗 [J].中国普通外科杂志, 2008, 17(6): 602-604..
- 6. 孙尚锋, 黄宏伟, 曹峰, 等.布加综合征治疗的研究进展 [J].中国现代普通外科进展, 2011, 14(1):52-54..
- 7. Wang ZG, Zhang FJ, Yi MQ, et al.Evolution of management for Budd-chiari syndrome: a team’s view from 2 564 patients [J].ANZ J Surg, 2005, 75(1-2): 55-63..
- 8. 王友琼.布-加综合征临床治疗研究( 附9 例分析) [J].当代医学, 2009, 15(6): 35..
- 9. 韩冰, 杨庆祥, 周玮娜, 等. 超声监测IVC 内支架置入并球囊扩张术治疗布-加综合征 [J].中国超声医学杂志, 1995, 11 (10): 748-750..
- 10. 陈世远, 高涌, 聂中林.B 超引导下肝静脉型布加综合征的介入治疗体会 [J].中华全科医学, 2011, 9(5): 713-714..
- 11. 张小明, 李清乐.布加综合征诊治现状 [J].中国医学科学院学报, 2007, 29(1): 25-28..
- 12. 李春民, 卞策, 汪忠镐.布-加综合征的个体化手术治疗 [J].中国普外基础与临床杂志2012 年1 月第19 卷第1 期 Chin J Bases ? 76 ? Clin General Surg, Vol. 19, No. 1, Jan. 2012中国普外基础与临床杂志, 2010, 17(12): 1306-1307..
- 13. 李震, 汪忠镐, 霍小森, 等.腹水静脉回输在重症布加综合征治疗中的作用 [J].中国普外基础与临床杂志, 2010,17(8):828-831, 836..
- 14. 李晓强, 余朝文, 吴允明.下腔静脉及肝静脉短段病变型布-加综合征的外科治疗 [J].中华普通外科杂志, 2001, 16(5):23-25..
- 15. 汪忠镐, 马颂章, 王仕华, 等.布-加综合征根治性矫正术式的探讨: 附37 例报告 [J].中华胸心血管外科杂志, 1995,11(3): 132-134..
- 16. 余军, 汪忠镐.下腔静脉内球囊成形支架置放加肠腔分流术治疗布-加综合征 [J].普外临床, 1995, 10(5): 307-308..
- 17. 陈学明, 汪忠镐, 尹振明, 等.布-加综合征452 例术后并发症的处理 [J].中华普通外科杂志, 1999, 14(6): 417-420..
- 18. 魏志新.肠腔分流或联合下腔静脉内支架置入术治疗布-加综合征 [J].中国普外基础与临床杂志, 2001, 8(4): 265-266..
- 19. 李晓东, 陈学明, 汪忠镐, 等.肝外型门静脉高压症外科治疗42 例经验 [J]. 中国普外基础与临床杂志, 2002, 9(2): 122-123.
- 20. 李震, 贾如冰, 汪忠镐, 等.附脐静脉在门静脉高压分流术中的应用 [J].中国普外基础与临床杂志, 2010, 17(2): 180-181.
- 21. 侯钰, 孙广新, 杨俊山.门静脉高压时脐静脉或附脐静脉的血流动力学改变及临床意义 [J].肝胆外科杂志, 2004, 12(5):332-334..
- 22. 王欣博, 童中勋, 刘威, 等. 门静脉海绵样变性外科治疗的研究进展 [J]. 中国普外基础与临床杂志, 2008, 15(12):877-879.
- 23. 王曙光, 蔡景修, 刘子沛, 等.脐静脉桥式选择性分流术 [J].消化外科杂志, 2003, 2(4): 239-242..
- 24. 李震, 汪忠镐, 卞策, 等. 肠房转流通畅前提下并发顽固性腹水的治疗 [J]. 中国普外基础与临床杂志, 2009, 16(7):571-572..
- 25. 汪忠镐, 李震.我国血管外科的现状和发展 [J].中国普外基础与临床杂志, 2006, 13(6): 625-628.