Advances in Medical Imaging Evaluation of Fatty Liver_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

ZHAO Liming , YANG Ningjing , SONG Bin

Department of Radiolog y , West China Hospital , Sichuan Universit y , Chengdu 610041 , China;

Corresponding author：

Keywords：

Fatty liver; 　Sonography; 　　Computed tomography/X-ray　　Magnetic resonance imaging/functional

Video：

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Objective 　To evaluate the value of medical imaging technology in qualitative and quantitative diagnosis of liver steatosis. Methods 　To describe the current status and advancement s of medical imaging technology such as sonography , CT and MRI in qualitative and quantitative diagnosis of liver steatosis , and to cont rast their advantages and shortages. Results 　Sonography could be used as the primary screening and evaluate measures in qualitative and quantitative diagnosis of liver steatosis , and CT was more reliable in quantitative diagnosis , MRI had significant improving with its high sensitivity and specificity. Conclusion 　Medical imaging technology has significant clinical value in qualitative and quantitative diagnosis of liver steatosis , especially with the help of functional MR imaging techniques such as spect roscopy and chemical shif t Gradient-Echo technic.

Citation： ZHAO Liming,YANG Ningjing,SONG Bin. Advances in Medical Imaging Evaluation of Fatty Liver. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2008, 15(1): 68-70. doi: Copy

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1. <>[1]范建高,曾民德.脂肪肝的研究进展[J].胃肠病学和肝病学杂志,1999; 8(2)∶149.
2. 周永昌,郭万学主编.超声医学[M].第3版.北京:科学技术文献出版社,1992∶598.
3. 陈伟明,杨益虎,吴意.超声量化诊断均匀性脂肪肝的初步研究[J].中华实用中西医杂志,2005; 18(21)∶1453.
4. 盛明洪,吕斌,周兴祥,等.二维超声图像定量诊断脂肪肝病变程度的应用研究[J].临床超声医学杂志,2005; 7(1)∶18.
5. 陈苏宁,陆雯,胡小涛,等.用超声研究脂肪肝的血流动力学变化[J].上海医学影像,2005; 14(1)∶47.
6. Graif M,Yanuka M,Baraz M,et al.Quantitative estimation of attenuation in ultrasound video images:correlation with histology in diffuse liver disease[J].Invest Radiol,2000; 35(5)∶319.
7. 李汉英,袁莉芳,董常峰,等.超声组织定征对均匀性脂肪肝分度的测量研究[J].中国超声诊断杂志,2005; 6(4)∶261.
8. 刘云霞,王洁贞,刘建平,等.脂肪肝影像学诊断性试验的系统评价[J].中国医学科学院学报,2004; 26(5)∶580.
9. 李果珍,戴建平,王仪生,等主编.临床CT诊断学[M].第2版.北京:中国科学技术出版社,1994∶437.
10. 许骅,王蒿,耿道颖,等.CT定量分析脂肪肝的临床应用探讨[J].中国医学计算机成像杂志,2004; 10(4)∶250.
11. 贺文,钱林学,赵继学,等.CT定量诊断脂肪肝的临床研究[J].中华放射学杂志,2001; 35(11)∶829.
12. 徐芸,王振豫,宋燕,等.CT图像的面罩式覆盖法对脂肪肝脂肪浸润的定量分析及临床意义[J].中华消化杂志,2000; 20(6)∶422.
13. 刘军,高鑫,陈刚,等.CT定量评价脂肪肝[J].上海医学影像杂志,2002; 11(3)∶170.
14. Ricci C,Longo R,Gioulis E,et al.Noninvasive in vivo quantitative assessment of fat content in human liver[J].J Hepatol,1997; 27(1)∶108.
15. 李文政,彭光春,汤恢焕,等.脂肪肝CT、MRI定量诊断的对照实验研究[J].医学影像学杂志,2005; 15(4)∶294.
16. Qayyum A,Goh JS,Kakar S,et al.Accuracy of liver fat quantification at MR imaging:comparison of out-of-phase gradient-echo and fat-saturated fast spin-echo techniques--initial experience[J].Radiology,2005; 237(2)∶507.
17. Rinella ME,McCarthy R,Thakrar K,et al.Dual-echo,chemical shift gradient-echo magnetic resonance imaging to quantifyhepatic steatosis:implications for living liver donation[J].Liver Transpl,2003; 9(8)∶851.
18. Machann J,Thamer C,Schnoedt B,et al.Hepatic lipid accumulation in healthy subjects:a comparative study using spectral fat-selective MRI and volume-localized 1H-MR spectroscopy[J].Magn Reson Med,2006; 55(4)∶913.
19. 范明霞,田建明,陆建平,等.活体1H磁共振波谱分析在大鼠脂肪肝中应用价值的初步研究[J].中国影像技术,2004; 20(10)∶1503.
20. Soher BJ,Vermathen P,Schuff N,et al.Short TE in vivo 1H-MR spectroscopic imaging at 1.5 T:acquisition and automated spectral analysis[J].Magn Reson Imaging,2000; 18(9)∶1159.
21. Pollesello P,Masutti F,Crocè LS,et al.1H-NMR spectroscopic studies of lipid extracts from human fatty liver[J].Biochem Biophys Res Commun,1993; 192(3)∶1217.
22. Thomas EL,Hamilton G,Patel N,et al.Hepatic triglyceride content and its relation to body adiposity:a magnetic resonance imaging and proton magnetic resonance spectroscopy study[J].Gut,2005; 54(1)∶122.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Advances in Medical Imaging Evaluation of Fatty Liver

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