Characterization Value of Focal Hepatic Lesions with Feridexs-Enhanced MR Imaging_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

YANG Hanfeng , SONG Bin , ZHOU Xiangping , YU Jianqun , CHEN Weixia , CHEN Xian , SUN Jiayu , CHEN Fufu , ZHU Hongmei.

Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China;

Corresponding author：

Keywords：

Focal hepatic lesions Magnetic resonance imaging Reviewer operator characteristic curve Diagnosis

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【Abstract】Objective To compare radiologists’ performance on combined unenhanced and feridexs-enhanced MR imaging （MRI） with their performance on helical CT enhanced, unenhanced MRI, and feridexs-enhanced MR alone imaging for the characteristics of local hepatic lesions.
Methods MR images and CT scans obtained in 26 patients with 57 local hepatic lesions were analyzed with reviewer operator characteristic (ROC) curve analysis. The imaging of patient were divided into 4 groups including combined unenhanced and feridexs-enhanced MRI group, helical CT enhanced group, unenhanced MRI group, and feridexsenhanced MR alone group.
Results The combined approach resulted in larger area under the ROC curve (Az=0.926 0) and accuracy (86.8%),P＜0.05，as compared with the others methods. There were no significant differences among the other three methods.
Conclusion Feridexs-enhanced MRI was more accurate than enhanced helical CT scan in characterization of local hepatic lesion. The combined analysis of unenhanced and feridexs-enhanced images was more accurate in the characterization of focal hepatic lesions than was review of feridexs-enhanced images alone.

Citation： YANG Hanfeng,SONG Bin,ZHOU Xiangping,YU Jianqun,CHEN Weixia,CHEN Xian,SUN Jiayu,CHEN Fufu,ZHU Hongmei.. Characterization Value of Focal Hepatic Lesions with Feridexs-Enhanced MR Imaging. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2004, 11(5): 454-457下转465. doi: Copy

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7.	Nakayama M, Yamashita Y, Mitsuzaki K, et al. Improved tissue characterization of focal liver lesions with ferumoxideenhanced T1 and T2weighted MR imaging [Ｊ]. J Magn Reson Imaging, 2000; 11(6)∶647.
8.	Grangier C, Tourniaire J, Mentha G, et al. Enhancement of liver hemangiomas on T1weighted MR SE images by superparamagnetic iron oxide particles [Ｊ]. J Comput Assist Tomogr, 1994; 18(6)∶888.
9.	Sahani D, Saini S, Sharma R, et al. Dynamic T1weighted ferumoxides enhanced MRI for imaging liver hemangiomas: preliminary observations [Ｊ]. Abdom Imaging, 2001; 26(2)∶166.
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1. Seneterre E, Taourel P, Bouvier Y, et al. Detection of hepatic metastases: ferumoxidesenhanced MR imaging versus unenhanced MR imaging and CT during arterial portography [Ｊ]. Radiology, 1996; 200(3)∶785.
2. Soyer P. Will ferumoxidesenhanced MR imaging replace CT during arterial portography in the detection of hepatic metastases? Prologue to a promising future [Ｊ]. Radiology, 1996; 200(3)∶600.
3. Vogl TJ, Hammerstingl R, Schwarz W, et al. Superparamagnetic iron oxide——enhanced versus gadoliniumenhanced MR imaging for differential diagnosis of focal liver lesions [Ｊ]. Radiology, 1996; 198(3)∶881.
4. Ishida T, Murakami T, Kato N, et al. Superparamagnetic iron oxide enhanced magnetic resonance imaging of rat liver with hepatocellular carcinoma and benign hyperplastic nodule [Ｊ]. Invest Radiol, 1997; 32(5)∶282.
5. Grandin C, Van Beers BE, Robert A, et al. Benign hepatocellular tumors: MRI after superparamagnetic iron oxide administration [Ｊ]. J Comput Assist Tomogr, 1995; 19(3)∶412.
6. Paley MR, Mergo PJ, Torres GM, et al. Characterization of focal hepatic lesions with ferumoxidesenhanced T2weighted MR imaging [Ｊ]. AJR Am J Roentgenol, 2000; 175(1)∶159.
7. Nakayama M, Yamashita Y, Mitsuzaki K, et al. Improved tissue characterization of focal liver lesions with ferumoxideenhanced T1 and T2weighted MR imaging [Ｊ]. J Magn Reson Imaging, 2000; 11(6)∶647.
8. Grangier C, Tourniaire J, Mentha G, et al. Enhancement of liver hemangiomas on T1weighted MR SE images by superparamagnetic iron oxide particles [Ｊ]. J Comput Assist Tomogr, 1994; 18(6)∶888.
9. Sahani D, Saini S, Sharma R, et al. Dynamic T1weighted ferumoxides enhanced MRI for imaging liver hemangiomas: preliminary observations [Ｊ]. Abdom Imaging, 2001; 26(2)∶166.
10. 刘剑羽，谢敬霞，姚学会，等. 菲立磁增强MRI在肝脏局灶性病变的诊断价值 [Ｊ]. 临床放射学杂志， 2001； 20（4）∶256.
11. Oudkerk M, van den Heuvel AG, Wielopolski PA, et al. Hepatic lesions: detection with ferumoxideenhanced T1weighted MR imaging [Ｊ]. Radiology, 1997; 203(2)∶449.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Characterization Value of Focal Hepatic Lesions with Feridexs-Enhanced MR Imaging

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