THE PROBLEM AND ASPECT OF GASTRIC CANCER GENE THERAPY_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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陈道达 , 郑海

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Keywords：

胃癌; 基因治疗; 问题; 展望

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Citation： 陈道达,郑海. THE PROBLEM AND ASPECT OF GASTRIC CANCER GENE THERAPY. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2002, 9(3): 141-142. doi: Copy

1.	参考文献.
2.	Tanaka T,Kanai F,Lan KH, et al. Adenovirusmediated gene therapy of gastric carcinoma using cancerspecific gene expression in vivo [J]. Biochem Res Commun， 1997; 231∶775.
3.	Hart S,Knight A,Harbottle R, et al. Cell binding and internalization by filamentous phage displaying a cyclic ArgGlyAspcontaining peptide [J]. J Biologi Chemis, 1994; 269∶12468.
4.	Steele RJC, Thompson AM,Hall P, et al. The p53 tumor suppressor gene [J]. Br J Surg, 1988; 85∶1460.
5.	Ohashi M, Kanai F. Adenovirus mediated p53 tumor suppressor gene therapy for human gastric cancer cells in vitro and in vivo [J].Gut, 1999; 44∶366.
6.	Bouvet M, Ellis LM. Adenovirusmediated wildtype p53 gene transfer downregulates vascular endothelial growth factor expression and inhibits angeiogenesis in human colon cancer [J]. Cancer Res, 1998; 58∶2288.
7.	Lowe S, Ruley H. p53dependent apoptosis modulstes the cytotoxicity of anticancer agents [J]. Cell， 1993; 362∶847.
8.	Nakano H, Namatame K, Suzuki T, et al. The evaluation of proliferating activity in gastric carcinoma stained by proliferating cell nuclear antigen (PCNA) [J]. Nippon Geka Gakkai Zasshi, 1992; 93(2)∶216.
9.	Sakakura C, Hagiwara A. The antiproliferative effect of proliferating cell nuclear antigenspecific antisense oligonucleotides on human gastric cancer cell lines [J]. Surg Today, 1995; 25∶184.
10.	Yoshida K, Kawami H. Retovirally transmitted gene therapy for gastric carcinoma using herps simplex virus thymidine kinase gene [J]. Cancer, 1995; 75∶1467.
11.	Inaba M, Swada H. Circumvention of 5fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction [J]. Jap J Cancer Research, 1999; 90∶349.
12.	Freema SM, Abboud CN. The "bystander effect": tumour regression when a fraction to be tumour mass is geneticlly modified [J]. Cancer Research， 1993; 53∶5274.
13.	Tanaka F,Abe M. The antihuman tumour effect and generation of human cytotoxic T cells in SCID mice given human periperal blood lymphocytes by the in vivo transfer of the IL6 gene using adenovirus vector [J]. Cancer Research, 1997; 57∶1335.
14.	Tagawa M, Goto S. Reduced tumorigenicity of human gastric carcinoma cells engeered to produce IL2 in SCID mice reconstituted with periperal blood cells from cancer patients [J]. Cancer Letters, 1998; 123∶517.

1. 参考文献.
2. Tanaka T,Kanai F,Lan KH, et al. Adenovirusmediated gene therapy of gastric carcinoma using cancerspecific gene expression in vivo [J]. Biochem Res Commun， 1997; 231∶775.
3. Hart S,Knight A,Harbottle R, et al. Cell binding and internalization by filamentous phage displaying a cyclic ArgGlyAspcontaining peptide [J]. J Biologi Chemis, 1994; 269∶12468.
4. Steele RJC, Thompson AM,Hall P, et al. The p53 tumor suppressor gene [J]. Br J Surg, 1988; 85∶1460.
5. Ohashi M, Kanai F. Adenovirus mediated p53 tumor suppressor gene therapy for human gastric cancer cells in vitro and in vivo [J].Gut, 1999; 44∶366.
6. Bouvet M, Ellis LM. Adenovirusmediated wildtype p53 gene transfer downregulates vascular endothelial growth factor expression and inhibits angeiogenesis in human colon cancer [J]. Cancer Res, 1998; 58∶2288.
7. Lowe S, Ruley H. p53dependent apoptosis modulstes the cytotoxicity of anticancer agents [J]. Cell， 1993; 362∶847.
8. Nakano H, Namatame K, Suzuki T, et al. The evaluation of proliferating activity in gastric carcinoma stained by proliferating cell nuclear antigen (PCNA) [J]. Nippon Geka Gakkai Zasshi, 1992; 93(2)∶216.
9. Sakakura C, Hagiwara A. The antiproliferative effect of proliferating cell nuclear antigenspecific antisense oligonucleotides on human gastric cancer cell lines [J]. Surg Today, 1995; 25∶184.
10. Yoshida K, Kawami H. Retovirally transmitted gene therapy for gastric carcinoma using herps simplex virus thymidine kinase gene [J]. Cancer, 1995; 75∶1467.
11. Inaba M, Swada H. Circumvention of 5fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction [J]. Jap J Cancer Research, 1999; 90∶349.
12. Freema SM, Abboud CN. The "bystander effect": tumour regression when a fraction to be tumour mass is geneticlly modified [J]. Cancer Research， 1993; 53∶5274.
13. Tanaka F,Abe M. The antihuman tumour effect and generation of human cytotoxic T cells in SCID mice given human periperal blood lymphocytes by the in vivo transfer of the IL6 gene using adenovirus vector [J]. Cancer Research, 1997; 57∶1335.
14. Tagawa M, Goto S. Reduced tumorigenicity of human gastric carcinoma cells engeered to produce IL2 in SCID mice reconstituted with periperal blood cells from cancer patients [J]. Cancer Letters, 1998; 123∶517.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

THE PROBLEM AND ASPECT OF GASTRIC CANCER GENE THERAPY

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