Clinical Study of Detectable Rate of IntraAbdominal Free Cancer Cells and Hyperthermic Peritoneal Perfusion Chemotherapy of Patients with Gastric Cancer_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

Department of General Surgery, The 309th Hospital of PLA, Beijing 100091;

Corresponding author：

Keywords：

Gastric cancerFree cancer cellHyperthermic peritoneal perfusion chemotherapy

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To evaluate the rational of peritoneal warm perfusion chemotherapy after the operation. MethodsOne hundred and two patients with gastric cancer were included in this study. One hundred milliliter of peritoneal fluid were collected respectively after opening the abdomen,before closing the peritoneal cavity,and after hyperthermic peritoneal perfusion chemotherapy for free cancer cells examination. ResultsAfter opening the abdomen, the positive rate of free cancer cells was 36.3%(37/102), and the positive rate before closure of peritoneal cavity was 52.9%(54/102), 31 cases of free cancer cells were found killed after the warm perfusion chemotherapy,the effect rate was 57.4%(31/54).The free cancer cells positive rate related to the tumor infiltration depth, serous membrane invasion area and the type of histopathology. Conclusion In the peritoneal cavity of patients with gastric cancer, free cancer cells are able to survive and have a high degree of activity. Hyperthermic peritoneal perfusion chemotherapy is an effective method to kill free cancer cells.

Citation： HE Jianmiao,PU Yongdong,CAO Zhiyu,et al.. Clinical Study of Detectable Rate of IntraAbdominal Free Cancer Cells and Hyperthermic Peritoneal Perfusion Chemotherapy of Patients with Gastric Cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2002, 9(3): 156-158. doi: Copy

1.	杨镇.手术野血中脱落的肿瘤细胞 [J].国外医学外科学分册，1995; 22(5)∶298.
2.	Kaibara M,Litsuka M,Kimura M， et al.Relationship between area of serosal invasion and prognosis in patients with gastric carcinoma [J]. Cancer,1987; 60(1)∶136.
3.	刘庆华,陈峻青. 胃癌浆膜类型、病理特点与腹腔游离癌细胞关系的临床分析 [J]. 中华肿瘤杂志，1988; 10（6）∶430.
4.	中岛聪聪. 胃癌10 000例の表解析 [J]. 癌と化学疗法，1994; 21（11）∶1882.
5.	杨传欣.胃癌病人腹腔游离癌细胞检出率的研究 [J]. 中国肿瘤临床与康复，1996; 3（3）∶15.
6.	Litsuka Y, Kaneshima S, Tanida O, et al. Intraperitoneal free cancer cell and their viability in gastric cancer [J]. Cancer，1979; 44（8）∶1476.
7.	朱正纲，朱寿柱，尹浩然, 等. 腹腔内温热灌注疗法在防治胃癌术后腹膜复发中的临床意义 [J]. 中国实用外科杂志, 1995; 15（12）∶710.

1. 杨镇.手术野血中脱落的肿瘤细胞 [J].国外医学外科学分册，1995; 22(5)∶298.
2. Kaibara M,Litsuka M,Kimura M， et al.Relationship between area of serosal invasion and prognosis in patients with gastric carcinoma [J]. Cancer,1987; 60(1)∶136.
3. 刘庆华,陈峻青. 胃癌浆膜类型、病理特点与腹腔游离癌细胞关系的临床分析 [J]. 中华肿瘤杂志，1988; 10（6）∶430.
4. 中岛聪聪. 胃癌10 000例の表解析 [J]. 癌と化学疗法，1994; 21（11）∶1882.
5. 杨传欣.胃癌病人腹腔游离癌细胞检出率的研究 [J]. 中国肿瘤临床与康复，1996; 3（3）∶15.
6. Litsuka Y, Kaneshima S, Tanida O, et al. Intraperitoneal free cancer cell and their viability in gastric cancer [J]. Cancer，1979; 44（8）∶1476.
7. 朱正纲，朱寿柱，尹浩然, 等. 腹腔内温热灌注疗法在防治胃癌术后腹膜复发中的临床意义 [J]. 中国实用外科杂志, 1995; 15（12）∶710.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Clinical Study of Detectable Rate of IntraAbdominal Free Cancer Cells and Hyperthermic Peritoneal Perfusion Chemotherapy of Patients with Gastric Cancer

Abstract Full text Figures/Tables Video References Cited by

Format

Content