Application of Myocardial Contrast Echocardiography in Evaluation of Viable Myocardium_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

XU Lei , LIU Hongyu.

Department of Cardiovascular Surgery， First Affiliated Hospital of Harbin Medical University， Harbin 150001， P. R. China;

Corresponding author：

Keywords：

Myocardial contrast echocardiography; 　Viable myocardium; 　Revascularization

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Progress in the treatment of acute myocardial infarction (AMI)， chronic coronary artery disease and their immediate complications has led to an increasing number of surviving patients with residual left ventricular dysfunction. It has been shown that viable myocardium in post-AMI patients and chronic heart failure patients plays an important role in predicting their prognosis and making clinical decisions. Viable myocardium refers to myocardium with reversible contractile dysfunction that occurs in coronary ischemia or after ischemia-reperfusion, but still has contractile reserve. Myocardial microvascular integrity is in　correspondence with myocardial viability. Myocardial contrast echocardiography can evaluate the microvascular integrity of myocardial dysfunctional areas in patients with AMI or chronic coronary artery disease, detect viable myocardium， predict the potential for functional recovery in dysfunctional areas following reperfusion， and provide clinicians with valuable information for individualized treatment.

Citation： XU Lei,LIU Hongyu.. Application of Myocardial Contrast Echocardiography in Evaluation of Viable Myocardium. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2012, 19(5): 551-554. doi: Copy

1.	Cardiol， 2003， 41 （5）：827-833.
2.	McManus DD， Chinali M， Saczynski JS， et al. Thirty-year trends in heart failure in patients hospitalized with acute myocardial infarction. Am J Cardiol， 2011， 107 （3）：353-359.
3.	Rees G， Bristow JD， Kremkau EL， et al. Influence of aortocoronary bypass surgery on left ventricular performance. N Engl J Med， 1971， 284 （20）：1116-1120.
4.	Kloner RA， Bolli R， Marban E， et al. Medical and cellular implications of stunning， hibernation， and preconditioning：an NHLBI workshop.　Circulation， 1998， 97 （18）：1848-1867.
5.	Rahimtoola SH. The hibernating myocardium. Am Heart J， 1989， 117 （1）：211-221.
6.	Kaufmann BA， Wei K， Lindner JR. Contrast echocardiography. Curr Probl Cardiol， 2007， 32 （2）：51-96.
7.	Kaul S， Jayaweera AR. Coronary and myocardial blood volumes：noninvasive tools to assess the coronary microcirculation ?Circulation， 1997， 96（3）：719-724.
8.	Wei K， Jayaweera AR， Firoozan S， et al. Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion. Circulation， 1998， 97 （5）：473-483.
9.	Galiuto L， Locorotondo G， Paraggio L， et al. Characterization of microvascular and myocardial damage within perfusion defect area at myocardial　contrast echocardiography in the subacute phase of myocardial infarction. Eur Heart J Cardiovasc Imaging， 2012， 13 （2）：174-180.
10.	Ito H， Tomooka T， Sakai N， et al. Lack of myocardial perfusion immediately after successful thrombolysis：a predictor of poor recovery of left ventricular function in anterior myocardial infarction. Circulation， 1992， 85 （5）：1699-1705.
11.	Ohmori K， Cotter B， Leistad E， et al. Assessment of myocardial postreperfusion viability by intravenous contrast echocardiography：analysis of the intensity and texture of opacification. Circulation， 2001， 103 （15）：2021-2027.
12.	Dwivedi G， Janardhanan R， Hayat SA， et al. Prognostic value of myocardial viability detected by myocardial contrast echocardiography early after acute myocardial infarction. J Am Coll Cardiol， 2007， 50 （4）：327-334.
13.	Olszowska M， Kostkiewicz M， Podolec P， et al. Myocardial viabi-lity detected by myocardial contrast echocardiography—prognostic value in patients after myocardial infarction. Echocardiography， 2010， 27 （4）：430-434.
14.	Galiuto L， Garramone B， Scara A， et al. The extent of microvascular damage during myocardial contrast echocardiography is superior to other known indexes of post-infarct reperfusion in predicting left ventricular remodeling. J Am Coll Cardiol， 2008， 51 （5）：552-559.
15.	Balcells E， Powers ER， Lepper W， et al. Detection of myocardial viability by contrast echocardiography in acute infarction predicts recovery of resting function and contractile reserve. J Am Coll.
16.	Hayat SA， Senior R. Myocardial contrast echocardiography in ST elevation myocardial infarction：ready for prime time? Eur Heart J， 2008， 29 （3）：299-314.
17.	申屠伟慧，邓又斌，黄润青，等. 实时心肌造影超声心动图再充盈参数评估心肌梗死后心肌存活性. 中国超声医学杂志， 2008， 24 （4）：370-372.
18.	Hickman M， Janardhanan R， Dwivedi G， et al. Clinical significance of perfusion techniques utilising different physiological mechanisms to detect myocardial viability：a comparative study with myocardial contrast echocardiography and single photon emission computed tomography. Int J Cardiol， 2007， 114 （1）：139-140.
19.	Huang WC， Chiou KR， Liu CP， et al. Comparison of real-time contrast echocardiography and low-dose dobutamine stress echocardiography in predicting the left ventricular functional recovery in patients after acute myocardial infarction under different therapeutic intervention. Int J Cardiol， 2005， 104 （1）：81-91.
20.	Senior R， Swinburn JM. Incremental value of myocardial contrast echocardiography for the prediction of recovery of function in dobutamine nonresponsive myocardium early after acute myocardial infarction. Am J Cardiol， 2003， 91 （4）：397-402.
21.	Schinkel AF， Bax JJ， Poldermans D， et al. Hibernating myocardium：diagnosis and patient outcomes. Curr Probl Cardiol， 2007， 32 （7）：375-410.
22.	Fernandes DR， Tsutsui JM， Bocchi EA， et al. Qualitative and quantitative real time myocardial contrast echocardiography for detecting hibernating myocardium. Echocardiography， 2011， 28 （3）：342-349.
23.	Tousek P， Penicka M， Tintera J， et al. Identification of hibernating myocardium with myocardial contrast echocardiography：comparison with late gadolinium-enhanced magnetic resonance. Int J Cardiol， 2008， 128 （1）：117-120.
24.	Chelliah RK， Hickman M， Kinsey C， et al. Myocardial contrast echocardiography versus single photon emission computed tomography for assessment of hibernating myocardium in ischemic cardiomyopathy：preliminary qualitative and quantitative results. J Am Soc Echocardiogr， 2010， 23 （8）：840-847.
25.	Hickman M， Chelliah R， Burden L， et al. Resting myocardial blood flow， coronary flow reserve， and contractile reserve in hibernating myocardium：implications for using resting myocardial contrast echocardiography vs. dobutamine echocardiography for the detection of hibernating myocardium. Eur J Echocardiogr， 2010， 11 （9）：756-762.
26.	Korosoglou G， Hansen A， Hoffend J， et al. Comparison of real-time myocardial contrast echocardiography for the assessment of myocardial viability with fluomdeoxyglueose-18 positron emission tomography and dobutamine stress echocardiography. Am J Cardiol， 2004， 94 （5）：570-576.
27.	Meza MF， Ramee S， Collins T， et al. Knowledge of perfusion and contractile reserve improves the predictive value of recovery of regional myocardial function postrevascularization. A study using the combination of myocardial contrast echocardiography and dobutamine echocardiography. Circulation， 1997， 96 （10）：3459-3465.
28.	Nelson C， Marwick TH. Clinical decision-making and myocardial viability：current perspectives. Int Med J， 2005， 35 （2）：118-125.
29.	李东野. 存活心肌检测对冠心病血运重建治疗决策的影响. 中华临床医师杂志：电子版， 2009， 3 （7）：1094-1099.
30.	Slart RH， Bax JJ， van Veldhuisen DJ， et al. Imaging techniques in nuclear cardiology for the assessment of myocardial viability. Int J Cardiovasc Imaging， 2006， 22 （1）：63-80.

1. Cardiol， 2003， 41 （5）：827-833.
2. 　McManus DD， Chinali M， Saczynski JS， et al. Thirty-year trends in heart failure in patients hospitalized with acute myocardial infarction. Am J Cardiol， 2011， 107 （3）：353-359.
3. 　Rees G， Bristow JD， Kremkau EL， et al. Influence of aortocoronary bypass surgery on left ventricular performance. N Engl J Med， 1971， 284 （20）：1116-1120.
4. 　Kloner RA， Bolli R， Marban E， et al. Medical and cellular implications of stunning， hibernation， and preconditioning：an NHLBI workshop.　Circulation， 1998， 97 （18）：1848-1867.
5. 　Rahimtoola SH. The hibernating myocardium. Am Heart J， 1989， 117 （1）：211-221.
6. 　Kaufmann BA， Wei K， Lindner JR. Contrast echocardiography. Curr Probl Cardiol， 2007， 32 （2）：51-96.
7. 　Kaul S， Jayaweera AR. Coronary and myocardial blood volumes：noninvasive tools to assess the coronary microcirculation ?Circulation， 1997， 96（3）：719-724.
8. 　Wei K， Jayaweera AR， Firoozan S， et al. Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion. Circulation， 1998， 97 （5）：473-483.
9. 　Galiuto L， Locorotondo G， Paraggio L， et al. Characterization of microvascular and myocardial damage within perfusion defect area at myocardial　contrast echocardiography in the subacute phase of myocardial infarction. Eur Heart J Cardiovasc Imaging， 2012， 13 （2）：174-180.
10. 　Ito H， Tomooka T， Sakai N， et al. Lack of myocardial perfusion immediately after successful thrombolysis：a predictor of poor recovery of left ventricular function in anterior myocardial infarction. Circulation， 1992， 85 （5）：1699-1705.
11. 　Ohmori K， Cotter B， Leistad E， et al. Assessment of myocardial postreperfusion viability by intravenous contrast echocardiography：analysis of the intensity and texture of opacification. Circulation， 2001， 103 （15）：2021-2027.
12. 　Dwivedi G， Janardhanan R， Hayat SA， et al. Prognostic value of myocardial viability detected by myocardial contrast echocardiography early after acute myocardial infarction. J Am Coll Cardiol， 2007， 50 （4）：327-334.
13. 　Olszowska M， Kostkiewicz M， Podolec P， et al. Myocardial viabi-lity detected by myocardial contrast echocardiography—prognostic value in patients after myocardial infarction. Echocardiography， 2010， 27 （4）：430-434.
14. 　Galiuto L， Garramone B， Scara A， et al. The extent of microvascular damage during myocardial contrast echocardiography is superior to other known indexes of post-infarct reperfusion in predicting left ventricular remodeling. J Am Coll Cardiol， 2008， 51 （5）：552-559.
15. 　Balcells E， Powers ER， Lepper W， et al. Detection of myocardial viability by contrast echocardiography in acute infarction predicts recovery of resting function and contractile reserve. J Am Coll.
16. 　Hayat SA， Senior R. Myocardial contrast echocardiography in ST elevation myocardial infarction：ready for prime time? Eur Heart J， 2008， 29 （3）：299-314.
17. 　申屠伟慧，邓又斌，黄润青，等. 实时心肌造影超声心动图再充盈参数评估心肌梗死后心肌存活性. 中国超声医学杂志， 2008， 24 （4）：370-372.
18. 　Hickman M， Janardhanan R， Dwivedi G， et al. Clinical significance of perfusion techniques utilising different physiological mechanisms to detect myocardial viability：a comparative study with myocardial contrast echocardiography and single photon emission computed tomography. Int J Cardiol， 2007， 114 （1）：139-140.
19. 　Huang WC， Chiou KR， Liu CP， et al. Comparison of real-time contrast echocardiography and low-dose dobutamine stress echocardiography in predicting the left ventricular functional recovery in patients after acute myocardial infarction under different therapeutic intervention. Int J Cardiol， 2005， 104 （1）：81-91.
20. 　Senior R， Swinburn JM. Incremental value of myocardial contrast echocardiography for the prediction of recovery of function in dobutamine nonresponsive myocardium early after acute myocardial infarction. Am J Cardiol， 2003， 91 （4）：397-402.
21. 　Schinkel AF， Bax JJ， Poldermans D， et al. Hibernating myocardium：diagnosis and patient outcomes. Curr Probl Cardiol， 2007， 32 （7）：375-410.
22. 　Fernandes DR， Tsutsui JM， Bocchi EA， et al. Qualitative and quantitative real time myocardial contrast echocardiography for detecting hibernating myocardium. Echocardiography， 2011， 28 （3）：342-349.
23. 　Tousek P， Penicka M， Tintera J， et al. Identification of hibernating myocardium with myocardial contrast echocardiography：comparison with late gadolinium-enhanced magnetic resonance. Int J Cardiol， 2008， 128 （1）：117-120.
24. 　Chelliah RK， Hickman M， Kinsey C， et al. Myocardial contrast echocardiography versus single photon emission computed tomography for assessment of hibernating myocardium in ischemic cardiomyopathy：preliminary qualitative and quantitative results. J Am Soc Echocardiogr， 2010， 23 （8）：840-847.
25. 　Hickman M， Chelliah R， Burden L， et al. Resting myocardial blood flow， coronary flow reserve， and contractile reserve in hibernating myocardium：implications for using resting myocardial contrast echocardiography vs. dobutamine echocardiography for the detection of hibernating myocardium. Eur J Echocardiogr， 2010， 11 （9）：756-762.
26. 　Korosoglou G， Hansen A， Hoffend J， et al. Comparison of real-time myocardial contrast echocardiography for the assessment of myocardial viability with fluomdeoxyglueose-18 positron emission tomography and dobutamine stress echocardiography. Am J Cardiol， 2004， 94 （5）：570-576.
27. 　Meza MF， Ramee S， Collins T， et al. Knowledge of perfusion and contractile reserve improves the predictive value of recovery of regional myocardial function postrevascularization. A study using the combination of myocardial contrast echocardiography and dobutamine echocardiography. Circulation， 1997， 96 （10）：3459-3465.
28. 　Nelson C， Marwick TH. Clinical decision-making and myocardial viability：current perspectives. Int Med J， 2005， 35 （2）：118-125.
29. 　李东野. 存活心肌检测对冠心病血运重建治疗决策的影响. 中华临床医师杂志：电子版， 2009， 3 （7）：1094-1099.
30. 　Slart RH， Bax JJ， van Veldhuisen DJ， et al. Imaging techniques in nuclear cardiology for the assessment of myocardial viability. Int J Cardiovasc Imaging， 2006， 22 （1）：63-80.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Application of Myocardial Contrast Echocardiography in Evaluation of Viable Myocardium

Abstract Full text Figures/Tables Video References Cited by

Format

Content