Objective To investigate the applied significance of adjustable low-concentration of mixed oxygen
and nitrous oxide inhalation sedation combined with lidocaine local anesthesia in anorectal surgery.
Methods Three hundreds patients underwent anorectal surgery in our hospital were divided into control group (n=154) and observation group (n=146). Patients of control group underwent pure lidocaine local anesthesia, and patients of observation group underwent mixed oxygen and nitrous oxide sedation analgesia combined with lidocaine local anesthesia. Vital signs before and after operation as well as results of sedation and analgesia were compared between the 2 groups.
Results Anorectal surgeries of all patients were performed successfully. There were no significant differences on change of heart rate, blood pressure, and oxygen saturation between the 2 groups before and after operation (P>0.05). The operation time between the control group 〔(36.3±6.8) min〕 and observation group 〔(35.4±6.5) min〕 had no statistically significant difference(t=-0.607, P=0.544). The analgesic effects (Z=-6.859, P=0.000) and sedative effects (Z=-5.275, P=0.000) of obser-vation group were both better than those of control group.
Conclusions Low-concentration of mixed oxygen and nitrous oxide inhalation sedation combined with lidocaine local anesthesia can relieve the discomfort of fear and pain, no side-impacts on vital sign before and after operation were observed,and it has better effects of sedation and analgesia, therefore it can be recommended to clinical application.
Citation:
CHEN Ying,ZHU Cifang,ZHANG Liang. Application of Adjustable Low-Concentration of Mixed Oxygen and Nitrous Oxide Inhalation Sedation Combined with Lidocaine Local Anesthesia in Anorectal Surgery. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2013, 20(10): 1146-1149. doi:
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1. |
国家中医药管理局. 中医病证诊断疗效标准[M]. 南京:南京大学出版社, 1994:132-136.
|
2. |
Cohen LB, Delegge MH, Aisenberg J, et al. Aga institute reviewof endoscopic sedation[J]. Gastroenterology, 2007, 133(2):675-701.
|
3. |
中华口腔医学会. 口腔治疗中笑气-氧气吸入镇静技术应用操作指南(试行)[J]. 中华口腔医学杂志, 2010, 45(11):645-647.
|
4. |
李立成, 刘瑛. 术后疼痛评估及镇痛护理进展[J]. 沈阳医学院学报, 2010, 12(1):57-60.
|
5. |
陈律, 李桂云, 蔡卫新, 等. Ramsay评分在神经外科术后患者中应用的信度和效度[J]. 中国医药导刊, 2011, 13(12):2105-2106.
|
6. |
Martínez J, Casellas JA, Aparicio JR, et al. Safety of propofoladministration by the staff of a gastrointestinal endoscopy unit[J].Gastroenterol Hepatol, 2007, 30(3):105-109.
|
7. |
Morse JW, Fowler SA, Morse AL. Endoscopist-administered propofol:a retrospective safety study[J]. Can J Gastroenterol, 2008, 22(7):617-620.
|
8. |
叶燕婷. 无痛胃镜检查的整体护理效果分析[J]. 中国基层医药, 2010, 17(24):3439-3440.
|
9. |
Clark M, Brunick A. Handbook of nitrous oxide and oxygen sedation[M]. 2th ed. UK:Mosby Elsevier, 2003:1-256.
|
10. |
梁庆艳. 笑气清醒镇静在胃镜检查中的应用[J]. 医学理论与实践, 2011, 24(11):1294-1295.
|
11. |
刘冰, 朱伟, 闫维, 等. 笑气吸入对阻生齿拔除术局麻药镇疼效果的影响[J]. 实用口腔医学杂志, 2013, 29(1):80-82.
|
12. |
樊淑珍, 卫梅征, 郭巧荣. 笑气吸入镇痛在妇产科的临床效果观察[J]. 实用医技杂志, 2008, 15(19):2542-2543.
|
13. |
张海萍. 笑气镇痛仪用于人工流产320例的临床镇痛疗效分析[J]. 淮海医药, 2008, 26(2):147.
|
14. |
苏连明, 艾江, 孔祥红. 笑气吸入应用于胃镜检查的临床效果观察[J]. 中国全科医学, 2012, 15(17):2014-2015.
|
15. |
刘华, 刘希双, 尹晓燕, 等. 笑气吸入清醒镇静在胃镜检查中的作用[J]. 中国内镜杂志, 2012, 18(5):554-555.
|
16. |
董正谋, 蒋和田, 刘鲁川, 等. 笑气吸入清醒镇静法在阻生牙拔除术中的临床观察[J]. 第三军医大学学报, 2011, 33(10):1071-1074.
|
17. |
李阳毓, 印春铭. 复方利多卡因乳膏在局麻手术中应用的临床观察[J]. 中国误诊学杂志, 2008, 8(23):5585-5586.
|
18. |
张雪, 王世端, 潘维敏, 等. 利多卡因局部浸润对宫颈锥切手术异丙酚效应室浓度及血流动力学参数影响[J]. 青岛大学医学院学报, 2010, 46(5):437-440.
|
19. |
张宪生, 尹杰, 郭宏杰. 利多卡因局部浸润麻醉下周围动脉重建术在老年患者中的应用[J]. 中华老年多器官疾病杂志, 2011, 10(5):424-427.
|
20. |
闫素英, 李希平, 田璟. 腭大孔注射利多卡因肾上腺素混合液对鼻内镜术野出血的影响[J]. 中国微创外科杂志, 2012, 12(3):266-268.
|
21. |
杨宝峰. 药理学[M]. 第7版. 北京:人民卫生出版社, 2011:123-127.
|
22. |
中华口腔医学会. 口腔治疗中笑气-氧气吸入镇静技术管理规范[J]. 中华口腔医学杂志, 2010, 45(11):648-649.
|
23. |
Hale KJ;American Academy of Pediatrics Section on Pediatric Dentistry. Oral health risk assessment timing and establishment of the dental home[J]. Pediatrics, 2005, 111(5 Pt 1):1113-1116.
|
24. |
Hosey MT;UK National Clinical Guidelines in Pediatric Dentistry.UK National Clinical Guidelines in Paediatric Dentistry. Managinganxious children:the use of conscious sedation in paediatric den-tistry[J]. Int J Paediatr Dent, 2002, 12(5):359-372.
|
25. |
顾立芳. 笑气吸入性分娩镇痛的临床观察[J]. 实用医学杂志, 2005, 21(14):1577-1578.
|
26. |
成健康, 杜勇, 刘锄非, 等. 笑气清醒镇静术在胃镜检查中的应用[J]. 湖北医药学院学报, 2011, 30(5):535-536.
|
- 1. 国家中医药管理局. 中医病证诊断疗效标准[M]. 南京:南京大学出版社, 1994:132-136.
- 2. Cohen LB, Delegge MH, Aisenberg J, et al. Aga institute reviewof endoscopic sedation[J]. Gastroenterology, 2007, 133(2):675-701.
- 3. 中华口腔医学会. 口腔治疗中笑气-氧气吸入镇静技术应用操作指南(试行)[J]. 中华口腔医学杂志, 2010, 45(11):645-647.
- 4. 李立成, 刘瑛. 术后疼痛评估及镇痛护理进展[J]. 沈阳医学院学报, 2010, 12(1):57-60.
- 5. 陈律, 李桂云, 蔡卫新, 等. Ramsay评分在神经外科术后患者中应用的信度和效度[J]. 中国医药导刊, 2011, 13(12):2105-2106.
- 6. Martínez J, Casellas JA, Aparicio JR, et al. Safety of propofoladministration by the staff of a gastrointestinal endoscopy unit[J].Gastroenterol Hepatol, 2007, 30(3):105-109.
- 7. Morse JW, Fowler SA, Morse AL. Endoscopist-administered propofol:a retrospective safety study[J]. Can J Gastroenterol, 2008, 22(7):617-620.
- 8. 叶燕婷. 无痛胃镜检查的整体护理效果分析[J]. 中国基层医药, 2010, 17(24):3439-3440.
- 9. Clark M, Brunick A. Handbook of nitrous oxide and oxygen sedation[M]. 2th ed. UK:Mosby Elsevier, 2003:1-256.
- 10. 梁庆艳. 笑气清醒镇静在胃镜检查中的应用[J]. 医学理论与实践, 2011, 24(11):1294-1295.
- 11. 刘冰, 朱伟, 闫维, 等. 笑气吸入对阻生齿拔除术局麻药镇疼效果的影响[J]. 实用口腔医学杂志, 2013, 29(1):80-82.
- 12. 樊淑珍, 卫梅征, 郭巧荣. 笑气吸入镇痛在妇产科的临床效果观察[J]. 实用医技杂志, 2008, 15(19):2542-2543.
- 13. 张海萍. 笑气镇痛仪用于人工流产320例的临床镇痛疗效分析[J]. 淮海医药, 2008, 26(2):147.
- 14. 苏连明, 艾江, 孔祥红. 笑气吸入应用于胃镜检查的临床效果观察[J]. 中国全科医学, 2012, 15(17):2014-2015.
- 15. 刘华, 刘希双, 尹晓燕, 等. 笑气吸入清醒镇静在胃镜检查中的作用[J]. 中国内镜杂志, 2012, 18(5):554-555.
- 16. 董正谋, 蒋和田, 刘鲁川, 等. 笑气吸入清醒镇静法在阻生牙拔除术中的临床观察[J]. 第三军医大学学报, 2011, 33(10):1071-1074.
- 17. 李阳毓, 印春铭. 复方利多卡因乳膏在局麻手术中应用的临床观察[J]. 中国误诊学杂志, 2008, 8(23):5585-5586.
- 18. 张雪, 王世端, 潘维敏, 等. 利多卡因局部浸润对宫颈锥切手术异丙酚效应室浓度及血流动力学参数影响[J]. 青岛大学医学院学报, 2010, 46(5):437-440.
- 19. 张宪生, 尹杰, 郭宏杰. 利多卡因局部浸润麻醉下周围动脉重建术在老年患者中的应用[J]. 中华老年多器官疾病杂志, 2011, 10(5):424-427.
- 20. 闫素英, 李希平, 田璟. 腭大孔注射利多卡因肾上腺素混合液对鼻内镜术野出血的影响[J]. 中国微创外科杂志, 2012, 12(3):266-268.
- 21. 杨宝峰. 药理学[M]. 第7版. 北京:人民卫生出版社, 2011:123-127.
- 22. 中华口腔医学会. 口腔治疗中笑气-氧气吸入镇静技术管理规范[J]. 中华口腔医学杂志, 2010, 45(11):648-649.
- 23. Hale KJ;American Academy of Pediatrics Section on Pediatric Dentistry. Oral health risk assessment timing and establishment of the dental home[J]. Pediatrics, 2005, 111(5 Pt 1):1113-1116.
- 24. Hosey MT;UK National Clinical Guidelines in Pediatric Dentistry.UK National Clinical Guidelines in Paediatric Dentistry. Managinganxious children:the use of conscious sedation in paediatric den-tistry[J]. Int J Paediatr Dent, 2002, 12(5):359-372.
- 25. 顾立芳. 笑气吸入性分娩镇痛的临床观察[J]. 实用医学杂志, 2005, 21(14):1577-1578.
- 26. 成健康, 杜勇, 刘锄非, 等. 笑气清醒镇静术在胃镜检查中的应用[J]. 湖北医药学院学报, 2011, 30(5):535-536.