Objective To analyze the clinical features， common etiologies， prevention measurements of recurrent acute pancreatitis （AP）.
Methods The clinical characteristics and imaging examination data of 43 patients with recurrent AP were analyzed retrospectively， which was compared with the results of 258 patients with primary AP. The recurrence etiologies were analyzed.
Results There were no significant differences on the fever， jaundice， abdominal pain relief time， pancreatic local complications， and ratio of severe AP between two groups （P＞0.05）. Comparion of etiologies between recurrent AP and primary AP， cholecystitis and diet factor （alcoholic） had priority in patients with primary AP （P=0.038， P=0.006， respectively）， but the hyperlipidemic， duodenal nipple disease， and small stone in the common bile duct were the major etiologies in patients with recurrent AP （P=0.007， P=0.008， respectively）. No relapse was found within the follow up for 3 months to 2 years （the average time was 14.2 months）.
Conclusion Find out the exact etiology and performe correct therapy are the key to the treatment and prevention of recurrent AP.
Citation：
ZHENG Benbo,LIU Shan,YANG Yong. Clinical Features and Common Etiologies of Recurrent Acute Pancreatitis. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2012, 19(10): 1102-1104. doi:
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Saraswat VA， Sharma BC， Agarwal DK， et al. Biliary microlithiasis in patients with idiopathic acute pancreatitis and unexplained biliary pain：response to therapy[J]. J Gastroenterol Hepatol， 2004， 19(10)：1206-1211.
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Kamisawa T， Chari ST， Giday SA， et al. Clinical profile of autoimmune pancreatitis and its histological subtypes：an international multicenter survey[J]. Pancreas， 2011， 40(6)：809-814.
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- 1. Guda NM， Romagnuolo J， Freeman ML. Recurrent and relapsing pancreatitis[J]. Curr Gastroenterol Rep， 2011， 13(2)：140-149.
- 2. 中华医学会消化病学分会胰腺疾病学组. 中国急性胰腺炎诊治指南(草案)[J]. 中华消化杂志， 2004， 24(3)：190-192.
- 3. 中华医学会消化病学分会. 慢性胰腺炎诊治指南[J]. 胰腺病学， 2005， 5(2)：104-106.
- 4. Takeyama Y. Long-term prognosis of acute pancreatitis in Japan[J]. Clin Gastroenterol Hepatol， 2009， 7(11 Suppl)：S15-S17.
- 5. Nguyen GC， Rosenberg M， Chong RY， et al. Early cholecystectomy and ERCP are associated with reduced readmissions for acute biliary pancreatitis：a nationwide， population-based study[J]. Gastrointest Endosc， 2012， 75(1)：47-55.
- 6. 金安琴， 黄晓俊， 王伟， 等. 早期内镜治疗急性胆源性胰腺炎46例临床研究[J]. 中国普外基础与临床杂志， 2010， 17(10)：1001-1005.
- 7. Egawa N， Anjiki H， Takuma K， et al. Juxtapapillary duodenal diverticula and pancreatobiliary disease[J]. Dig Surg， 2010， 27(2)：105-109.
- 8. 王刚， 孙备， 姜洪池. 高脂血症急性胰腺炎的研究进展[J]. 中国普通外科杂志， 2005， 14(11)：857-859.
- 9. 刘山， 郑本波， 何永林. 早期血浆置换联合连续血液滤过治疗高血脂性重症急性胰腺炎的效果观察[J]. 中国现代医学杂志， 2009， 19(21)：3323-3325.
- 10. Saraswat VA， Sharma BC， Agarwal DK， et al. Biliary microlithiasis in patients with idiopathic acute pancreatitis and unexplained biliary pain：response to therapy[J]. J Gastroenterol Hepatol， 2004， 19(10)：1206-1211.
- 11. Kamisawa T， Chari ST， Giday SA， et al. Clinical profile of autoimmune pancreatitis and its histological subtypes：an international multicenter survey[J]. Pancreas， 2011， 40(6)：809-814.
- 12. Gullo L， Migliori M， Pezzilli R， et al. An update on recurrent acute pancreatitis：data from five European countries[J]. Am J Gastroenterol， 2002， 97(8)：1959-1962.
