Objective The survival data of patients with colon cancer who were treated by laparoscopic-assisted surgery and open surgery three years after operation were analyzed and contrasted, which provided data to support the future treatment.
Methods The 217 patients who were cured by laparoscopic-assisted surgery and 193 patients who were cured by open surgery were followed up, and the rates of local recurrence, metastasis, implantative, and survival were contrasted and analyzed.
Results Three years after laparoscopic-assisted surgery and open surgery, the disease-free survival rate was 86.2% （187/217） and 85.5% （165/193）, respectively, and the overall survival rate was 91.2% （198/217） and 92.7% （179/193）, respectively, the difference between the two groups was not statistic significance（P＞0.05）. The differences of the rates of local recurrence, metastasis, and implantative between the two groups were not statistic significance（P＞0.05）.
Conclusions Laparoscopic-assisted surgery is similar with open surgery in the rates of local recurrence, forward metastasis, and overall survival. So laparoscopic-assisted surgery is a safe and radical curative surgery.
Citation：
YIN Hongzhuan,YAN Zhaopeng,SUN Wei,YIN Jianqiao,LIU Baolin,SU Qi,.. Short-Term Outcome Analysis of Laparoscopy-Assisted Versus Open Surgery for Colon Cancer. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2012, 19(6): 646-648. doi:
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Mishima H， Ikenaga M， Tsujinaka T， et al. FOLFOX [J]. GanTo Kagaku Ryoho， 2006， 33(7)：911-914.
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徐忠法， 孙燕来. 结肠癌的分期与腹腔镜结肠癌手术治疗的选择 [J]. 肿瘤预防与治疗， 2008， 21(3)：239-241.
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Jayne DG， Guillou PJ， Thorpe H， et al. Randomized trial of laparoscopic-assisted resection of colorectal carcinoma：3-year results of the UK MRC CLASICC Trial Group[J]. J Clin Oncol，2007， 25(21)：3061-3068.
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Cummings LC， Delaney CP， Cooper GS. Laparoscopic versus open colectomy for colon cancer in an older population：a cohort study [J]. World J Surg Oncol， 2012， 10：31.
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王琛， 李徐生， 徐小东， 等. 腹腔镜外科技术在结肠癌治疗中的临床应用 [J]. 中国普外基础与临床杂志， 2007(6)：644-645.
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| 11. |
郁宝铭. 结直肠癌外科治疗的现状和展望 [J]. 中国普外基础与临床杂志，2008， 15(9)：631-636.
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黄石川， 游志坚， 梁子君， 等. 腹腔镜结直肠肿瘤手术18 例报道 [J]. 中国普外基础与临床杂志， 2008， 15(10)：722-725.
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汪路， 孟庆勇， 王小军， 等. 结肠癌根治术后复发转移危险因素分析 [J]. 中国肿瘤，2007， 16(8)：646-648.
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| 14. |
Tanis E， van Geloven AA， Bemelman WA， et al. A comparison of short-term outcome after laparoscopic， transverse， and midline right-sided colectomy [J]. Int J Colorectal Dis， 2012 Jan 17.[Epub ahead of print].
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| 15. |
Khan JS， Hemandas AK， Flashman KG， et al. Clinical outcome of laparoscopic and open colectomy for right colonic carcinoma [J]. Ann R Coll Surg Engl， 2011， 93(8)：603-607.
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| 16. |
吕成余， 时开网， 蔡永东， 等. 结直肠癌211 例外科治疗体会[J]. 中国普外基础与临床杂志， 2008， 15(10)：771-772.
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| 17. |
Watanabe M， Hasegawa H， Yamamoto S， et al. Laparoscopic surgery for stage I colorectal cancer [J]. Surg Endosc， 2003，17(8)：1274-1277.
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| 18. |
Okuda J， Tanigawa M. Laparoscopy-assisted surgery for colon cancer [J]. Gan To Kagaku Ryoho， 2008， 35(11)：1847-1849.
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| 19. |
Lacy AM， Delgado S， Castells A， et al. The long-term results of a randomized clinical trial of laparoscopy-assisted versus open surgery for colon cancer [J]. Ann Surg， 2008， 248(1)：1-7.
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| 20. |
Bilimoria KY， Bentrem DJ， Merkow RP， et al. Laparoscopicassisted vs. open colectomy for cancer：comparison of short-term outcomes from 121 hospitals [J]. J Gastrointest Surg， 2008，12(11)：2001-2009.
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| 21. |
Kuhry E， Schwenk W， Gaupset R， et al. Long-term outcome of laparoscopic surgery for colorectal cancer：a cochrane systematic review of randomised controlled trials [J]. Cancer Treat Rev，2008， 34(6)：498-504.
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| 22. |
Varela JE， Asolati M， Huerta S， et al. Outcomes of laparoscopic and open colectomy at academic centers [J]. Am J Surg， 2008，196(3)：403-406.
|
| 23. |
Tong DK， Law WL. Laparoscopic versus open right hemicolectomy for carcinoma of the colon [J]. JSLS， 2007， 11(1)：76-80.
|
| 24. |
Hayes JL， Hansen P. Is laparoscopic colectomy for cancer costeffective relative to open colectomy? [J]. ANZ J Surg， 2007，77(9)：782-786.
|
| 25. |
Stucky CC， Pockaj BA， Novotny PJ， et al. Long-term follow-up and individual item analysis of quality of life assessments related to laparoscopic-assisted colectomy in the COST trial 93-46-53(INT 0146) [J]. Ann Surg Oncol， 2011， 18(9)：2422-2431.
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| 26. |
Ohtani H， Tamamori Y， Arimoto Y， et al. A meta-analysis of the short- and long-term results of randomized controlled trials that compared laparoscopy-assisted and open colectomy for colon cancer [J]. J Cancer， 2012， 3：49-57.
|
- 1. 吴在德， 吴肇汉. 外科学 [M]. 第7 版. 北京：人民卫生出版社， 2008：488-489.
- 2. 中华医学会外科学分会腹腔镜与内镜外科学组. 腹腔镜结直肠癌根治术指南(2006 版) [J]. 外科理论与实践， 2006，5(11)：462-464.
- 3. 万德森. 临床肿瘤学 [M]. 第2 版. 北京：科学出版社，2005：348.
- 4. Medinger M， Steinbild S， Mross K. Adjuvant and palliativeanticancer treatment of colon carcinoma in 2004 [J]. Praxis (Bern1994)， 2004， 93(40)：1633-1644.
- 5. Mishima H， Ikenaga M， Tsujinaka T， et al. FOLFOX [J]. GanTo Kagaku Ryoho， 2006， 33(7)：911-914.
- 6. 徐忠法， 孙燕来. 结肠癌的分期与腹腔镜结肠癌手术治疗的选择 [J]. 肿瘤预防与治疗， 2008， 21(3)：239-241.
- 7. Fleshman J， Sargent DJ， Green E， et al. Laparoscopic colectomyfor cancer is not inferior to open surgery based on 5-year data from the COST Study Group trial [J]. Ann Surg， 2007， 246(4)：655-662.
- 8. Jayne DG， Guillou PJ， Thorpe H， et al. Randomized trial of laparoscopic-assisted resection of colorectal carcinoma：3-year results of the UK MRC CLASICC Trial Group[J]. J Clin Oncol，2007， 25(21)：3061-3068.
- 9. Cummings LC， Delaney CP， Cooper GS. Laparoscopic versus open colectomy for colon cancer in an older population：a cohort study [J]. World J Surg Oncol， 2012， 10：31.
- 10. 王琛， 李徐生， 徐小东， 等. 腹腔镜外科技术在结肠癌治疗中的临床应用 [J]. 中国普外基础与临床杂志， 2007(6)：644-645.
- 11. 郁宝铭. 结直肠癌外科治疗的现状和展望 [J]. 中国普外基础与临床杂志，2008， 15(9)：631-636.
- 12. 黄石川， 游志坚， 梁子君， 等. 腹腔镜结直肠肿瘤手术18 例报道 [J]. 中国普外基础与临床杂志， 2008， 15(10)：722-725.
- 13. 汪路， 孟庆勇， 王小军， 等. 结肠癌根治术后复发转移危险因素分析 [J]. 中国肿瘤，2007， 16(8)：646-648.
- 14. Tanis E， van Geloven AA， Bemelman WA， et al. A comparison of short-term outcome after laparoscopic， transverse， and midline right-sided colectomy [J]. Int J Colorectal Dis， 2012 Jan 17.[Epub ahead of print].
- 15. Khan JS， Hemandas AK， Flashman KG， et al. Clinical outcome of laparoscopic and open colectomy for right colonic carcinoma [J]. Ann R Coll Surg Engl， 2011， 93(8)：603-607.
- 16. 吕成余， 时开网， 蔡永东， 等. 结直肠癌211 例外科治疗体会[J]. 中国普外基础与临床杂志， 2008， 15(10)：771-772.
- 17. Watanabe M， Hasegawa H， Yamamoto S， et al. Laparoscopic surgery for stage I colorectal cancer [J]. Surg Endosc， 2003，17(8)：1274-1277.
- 18. Okuda J， Tanigawa M. Laparoscopy-assisted surgery for colon cancer [J]. Gan To Kagaku Ryoho， 2008， 35(11)：1847-1849.
- 19. Lacy AM， Delgado S， Castells A， et al. The long-term results of a randomized clinical trial of laparoscopy-assisted versus open surgery for colon cancer [J]. Ann Surg， 2008， 248(1)：1-7.
- 20. Bilimoria KY， Bentrem DJ， Merkow RP， et al. Laparoscopicassisted vs. open colectomy for cancer：comparison of short-term outcomes from 121 hospitals [J]. J Gastrointest Surg， 2008，12(11)：2001-2009.
- 21. Kuhry E， Schwenk W， Gaupset R， et al. Long-term outcome of laparoscopic surgery for colorectal cancer：a cochrane systematic review of randomised controlled trials [J]. Cancer Treat Rev，2008， 34(6)：498-504.
- 22. Varela JE， Asolati M， Huerta S， et al. Outcomes of laparoscopic and open colectomy at academic centers [J]. Am J Surg， 2008，196(3)：403-406.
- 23. Tong DK， Law WL. Laparoscopic versus open right hemicolectomy for carcinoma of the colon [J]. JSLS， 2007， 11(1)：76-80.
- 24. Hayes JL， Hansen P. Is laparoscopic colectomy for cancer costeffective relative to open colectomy? [J]. ANZ J Surg， 2007，77(9)：782-786.
- 25. Stucky CC， Pockaj BA， Novotny PJ， et al. Long-term follow-up and individual item analysis of quality of life assessments related to laparoscopic-assisted colectomy in the COST trial 93-46-53(INT 0146) [J]. Ann Surg Oncol， 2011， 18(9)：2422-2431.
- 26. Ohtani H， Tamamori Y， Arimoto Y， et al. A meta-analysis of the short- and long-term results of randomized controlled trials that compared laparoscopy-assisted and open colectomy for colon cancer [J]. J Cancer， 2012， 3：49-57.
