Analysis of Risk Factors of Early Postoperative Complications after Pancreaticoduodenectomy (Report of 71 Cases)_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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吕飞飞 , 赵海平

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胰十二指肠切除术,并发症

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【摘要】目的总结胰十二指肠切除术(pancreaticoduodenectomy,PD)早期（术后30 d内）并发症发生的相关危险因素，指导围手术期患者的有效治疗。方法回顾性分析2002年1月至2007年1月期间71例行PD的临床资料,分析早期并发症的发生情况及相关影响因素。结果 PD术后并发症发生率为46.5%(33/71)。Logistic多变量分析确定了2个与PD术后早期并发症相关的变量即术中输血量≥800 ml(OR=8.227)和胰液引流入肠道(OR=5.134)。结论 PD的手术风险目前仍较高，运用胰液外引流、加强围手术期处理是预防并发症的重要环节。

Citation： 吕飞飞,赵海平. Analysis of Risk Factors of Early Postoperative Complications after Pancreaticoduodenectomy (Report of 71 Cases). CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2008, 15(3): 205-206. doi: Copy

1.	Lin JW, Cameron JL, Yeo CJ, et al. Risk factors and outcomes in postpancreaticoduodenectomy pancreaticocutaneous fistula [Ｊ]. J Gastrointest Surg, 2004; 8(8)∶951.
2.	孙汴生，杨汉新，王勇强，等. 胰管引流与非引流在预防胰十二指肠切除术后胰瘘发生的作用观察[Ｊ]. 中国普外基础与临床杂志， 2002； 9（2）∶118.
3.	Topal B, Aerts R, Hendrickx T, et al. Determinants of complications in pancreaticoduodenectomy [Ｊ]. Eur J Surg Oncol, 2007; 33(4)∶488.
4.	Gulbinas A, Barauskas G, Pundzius J, et al. The impact of morphologic and physiologic peculiarities of the pancreas on pancreas-related complications following pancreatoduodenectomy [Ｊ]. Medicina (Kaunas), 2003; 39(2)∶151.
5.	Roder JD, Stein HJ, Bttcher KA, et al. Stented versus nonstented pancreaticojejunostomy after pancreatoduodenectomy: a prospective study [Ｊ]. Ann Surg, 1999; 229(1)∶41.
6.	Makary MA, Winter JM, Cameron JL, et al. Pancreaticoduodenectomy in the very elderly [Ｊ]. J Gastrointest Surg, 2006; 10(3)∶347.
7.	胡万青, 江艺, 吕立志. 胰十二指肠切除术的并发症和术前相关因素分析(附67 例报告) [Ｊ]. 中国普外基础与临床杂志， 2002； 9（2）∶123.
8.	Cheng OB, Zhang BH, Luo XJ, et al. Risk factors of early complications after pancreaticoduodenectomy in 200 consecutive patients [Ｊ]. Chinese-German J Clin Onco, 2005； 4(4)∶194.
9.	徐来喜，余少鸿，何振平. 胰十二指肠切除术后严重并发症的防治体会[Ｊ]. 中国普外基础与临床杂志， 2006； 13（6）∶714.
10.	戴存才, 苗毅, 刘训良. 专业组与非专业组胰十二指肠切除之比较 [Ｊ]. 中华肝胆外科杂志， 2005; 11(10)∶665.

1. Lin JW, Cameron JL, Yeo CJ, et al. Risk factors and outcomes in postpancreaticoduodenectomy pancreaticocutaneous fistula [Ｊ]. J Gastrointest Surg, 2004; 8(8)∶951.
2. 孙汴生，杨汉新，王勇强，等. 胰管引流与非引流在预防胰十二指肠切除术后胰瘘发生的作用观察[Ｊ]. 中国普外基础与临床杂志， 2002； 9（2）∶118.
3. Topal B, Aerts R, Hendrickx T, et al. Determinants of complications in pancreaticoduodenectomy [Ｊ]. Eur J Surg Oncol, 2007; 33(4)∶488.
4. Gulbinas A, Barauskas G, Pundzius J, et al. The impact of morphologic and physiologic peculiarities of the pancreas on pancreas-related complications following pancreatoduodenectomy [Ｊ]. Medicina (Kaunas), 2003; 39(2)∶151.
5. Roder JD, Stein HJ, Bttcher KA, et al. Stented versus nonstented pancreaticojejunostomy after pancreatoduodenectomy: a prospective study [Ｊ]. Ann Surg, 1999; 229(1)∶41.
6. Makary MA, Winter JM, Cameron JL, et al. Pancreaticoduodenectomy in the very elderly [Ｊ]. J Gastrointest Surg, 2006; 10(3)∶347.
7. 胡万青, 江艺, 吕立志. 胰十二指肠切除术的并发症和术前相关因素分析(附67 例报告) [Ｊ]. 中国普外基础与临床杂志， 2002； 9（2）∶123.
8. Cheng OB, Zhang BH, Luo XJ, et al. Risk factors of early complications after pancreaticoduodenectomy in 200 consecutive patients [Ｊ]. Chinese-German J Clin Onco, 2005； 4(4)∶194.
9. 徐来喜，余少鸿，何振平. 胰十二指肠切除术后严重并发症的防治体会[Ｊ]. 中国普外基础与临床杂志， 2006； 13（6）∶714.
10. 戴存才, 苗毅, 刘训良. 专业组与非专业组胰十二指肠切除之比较 [Ｊ]. 中华肝胆外科杂志， 2005; 11(10)∶665.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Analysis of Risk Factors of Early Postoperative Complications after Pancreaticoduodenectomy (Report of 71 Cases)

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