Impact of Immunonutrition in Organ Transplantation_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

CIREN Sangzhu , WANG Zhengxia , ZHANG Hui , CHEN Xiaoli

Department of General Surgery, West China Hospital, Sichuan University, Chengdu 610041, China;

Corresponding author：

Keywords：

Immunonutrition; Organ transplantation

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Objective 　To investigate the impact of immunonutrition in organ transplantation.
Methods 　The literatures of recent years on the studies of immunonutrition in organ transplantation were reviewed.
Results 　Immunonutrition including ω-3 fatty acid and special amino acids etc could reduce inflamation and supress immunal response following organ transplantation markably.
Conclusion 　Application of immunonutrition associated with immunosupress could take the place of traditional steroids completely in the treatment following organ transplantation, even shorten clinical course of immunosupress.

Citation： CIREN Sangzhu,WANG Zhengxia,ZHANG Hui,CHEN Xiaoli. Impact of Immunonutrition in Organ Transplantation. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2007, 14(2): 243-244. doi: Copy

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1. 　魏晓平，李立. 他克莫司与环孢素A在器官移植中的应用比较 [J]. 中国普外基础与临床杂志， 2003； 10（4）∶415.
2. 　Alexander JW. Immunonutrition: the role of omega-3 fatty acids [J]. Nutrition， 1998; 14(7-8)∶627.
3. 　朱国超，陈知水. 染料木黄酮的免疫调节作用及其在器官移植中的应用 [J]. 细胞与分子免疫学杂志， 2006； 22（5）∶689.
4. 　Alexander JW. Influence of EPA and DHA intravenous fat emulsions on nitrogen retention and protein kinetics in burned rats [J]. Nutrition， 1999; 15(2)∶161.
5. 　王伟，仇巯东. 丙氨酰谷氨酰胺对肝移植术后病人蛋白质代谢及营养状况的影响 [J]. 肠外与肠内营养， 2006； 13（5）∶292.
6. 　Alexander JW. Role of immunonutrition in reducing complications following organ transplantation [J]. Transplant Proc， 2000; 32(3)∶574.
7. 　Alexander JW, Valente JF, Greenberg NA, et al. Dietary amino acids as new and novel agents to enhance allograft survival [J]. Nutrition， 1999; 15(2)∶130.
8. 　Gibson SW, Valente JF, Alexander JW, et al. Nutritional immunomodulation leads to enhanced allograft survival in combination with cyclosporine A and rapamycin, but not FK506 [J]. Transplantation， 2000; 69(10)∶2034.
9. 　Alexander JW, Stanley LL, Ofstedal TL, et al. Transplantation without steroids [J]. Transplant Proc， 2002; 34(6)∶2076.
10. 　武正山，钱建民，孔连宝，等. 肝移植术后早期肠内营养支持的临床应用[J]. 中国普外基础与临床杂志， 2004； 11（3）∶255.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Impact of Immunonutrition in Organ Transplantation

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