• Department of General Surgery, Third Affiliated Hospital, Beijing University of Medical Sciences, Beijing 100083;
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Objective  To study the value of intraperitoneal chemotherapy in the treatment of gastrointestinal malignancies. Methods  The current literature on intraperitoneal chemotherapy was reviewed.
Results  Following intraperitoneal injection, the concentration of drugs in the peritoneum and in the portal vein was high, lasting and sustained. Early postoperative chemotherapy showed better results. Port-A-Cath provides a safe and suitable drug delivery system. Complications were mild.
Conclusion  Intraperitoneal chemotherapy presents significant pharmacokinetic and clinical potentials in the treatment of gastrointestinal malignancies, as well as in the prevention and treatment of postoperative metastasis.

Citation: Foute Nelong J.C.,YAN Nansheng,ZHOU Xiaosi.. INTRAPERITONEAL CHEMOTHERAPY IN THE TREATMENT OF GASTROINTESTINAL MALIGNANCIES. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2000, 7(3): 191-193. doi: Copy