Objective To analyze the relation between the mode of delivery and postpartum lower extremity deep venous thrombosis （DVT）， and discuss the therapy methods.
Methods The clinical data of 48 patients with postpartum lower extremity DVT from 2006 to 2012 in this hospital were analyzed retrospectively.
Results There were 15 897 patients with the delivery， of whom were 10 097 cases of cesarean section and 5 800 cases of spontaneous delivery， the incidence rate of lower extremity DVT in the patients with cesarean section was significantly higher than that in the patients with spontaneous delivery〔0.41% （41/10 097） versus 0.12% （7/5 800）， χ2=9.94，P＜0.005〕. The higher incidence rate of cesarean section， the higher incidence rate of lower extremity DVT， which was a positive correlation between them （rs=0.87，P＜0.05）. Forty-three cases were only treated by drug therapy， 2 cases were performed operation combined with drug therapy， and 5 cases were placed the inferior vena cava filter. Forty-eight cases were cured and discharged.
Conclusions The incidence rate of lower extremity DVT of cesarean section is higher as compared with the spontaneous delivery. The thrombolysis and （or） anticoagulation therapy is an effective way in the treatment for DVT. Controlling indications of cesarean section and early postpartum out-of-bed can decrease the DVT.
Citation：
Lingjuan,YANG Yong,YANG Guokai,WAN Jia,XIE Hailiang. Study of Relation Between Mode of Delivery and Postpartum Lower Extremity Deep Venous Thrombosis. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2013, 20(2): 143-146. doi:
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中华医学会外科学分会血管外科学组. 深静脉血栓形成的诊断和治疗指南(第2版)[J]. 中华外科杂志， 2012， 50(7) ：611-614.
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汪忠镐， 李震. 深静脉血栓治疗的商榷[J]. 中国普外基础与临床杂志， 2012， 19(11)：1149-1151.
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Acharya G， Singh K， Hansen JB， et al. Catheter-directed thrombolysis for the management of postpartum deep venous thrombosis[J]. Acta Obstet Gynecol Scand， 2005， 84(2)：155-158.
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马志强， 魏松洋， 杨瑞丽， 等. 下肢深静脉血栓形成的治疗经验[J]. 中国普外基础与临床杂志， 2011， 18(2)：202-203.
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中华医学会外科学分会血管外科学组. 深静脉血栓形成的诊断和治疗指南[J]. 中华普通外科杂志， 2008， 23(3)：235-238.
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， 31(3)：167-175.
|
- 1. James AH， Tapson VF， Goldhaber SZ. Thrombosis during pregnancy and the postpartum period[J]. Am J Obstet Gynecol， 2005， 193(1)：216-219.
- 2. 狄文， 吴震溟. 重视妇产科静脉血栓性疾病的预防和处理[J]. 中国实用妇科与产科杂志， 2009， 25(5)：324-326.
- 3. Simpson EL， Lawrenson RA， Nightingale AL， et al. Venous thromboembolism in pregnancy and the puerperium：incidence and additional risk factors from a London perinatal database[J]. BJOG， 2001， 108(1)：56-60.
- 4. Garcia DA， Baglin TP， Weitz JI， et al. American College of Chest Physicians. Parenteral anticoagulants：Antithrombotic Therapy and Prevention of Thrombosis， 9th ed：American Collegeof Chest Physicians Evidence-Based Clinical Practice Guidelines[J]. Chest， 2012， 141(2 Suppl)：e24S-e43S.
- 5. Jacobsen AF， Dahm A， Bergrem A， et al. Risk of venous thrombosis in pregnancy among carriers of the factorⅤLeiden and the prothrombin gene G20210A polymorphisms[J]. J Thromb Haemost， 2010， 8(11)：2443-2449.
- 6. James AH， Grotegut CA， Brancazio LR， et al. Thromboembolismin pregnancy：recurrence and its prevention[J]. Semin Perinatol，.
- 7. 张柏根. 深静脉血栓形成//外科学[M]. 第7版. 北京：人民卫生出版社， 2008：617-620.
- 8. O’Connor DJ， Scher LA， Gargiulo NJ 3rd， et al. Incidence and characteristics of venous thromboembolic disease during pregnancyand the postnatal period：a contemporary series[J]. Ann Vasc Surg， 2011， 25(1)：9-14.
- 9. 杨镛， 杨国凯， 万嘉. 下肢深静脉血栓的微创治疗//微创血管外科学[M]. 北京：科学出版社， 2011：426-445.
- 10. Popuri RK， Vedantham S. The role of thrombolysis in the clinicalmanagement of deep vein thrombosis[J]. Arterioscler Thromb Vasc Biol， 2011， 31(3)：479-484.
- 11. 中华医学会外科学分会血管外科学组. 深静脉血栓形成的诊断和治疗指南(第2版)[J]. 中华外科杂志， 2012， 50(7) ：611-614.
- 12. 汪忠镐， 李震. 深静脉血栓治疗的商榷[J]. 中国普外基础与临床杂志， 2012， 19(11)：1149-1151.
- 13. Acharya G， Singh K， Hansen JB， et al. Catheter-directed thrombolysis for the management of postpartum deep venous thrombosis[J]. Acta Obstet Gynecol Scand， 2005， 84(2)：155-158.
- 14. 马志强， 魏松洋， 杨瑞丽， 等. 下肢深静脉血栓形成的治疗经验[J]. 中国普外基础与临床杂志， 2011， 18(2)：202-203.
- 15. 中华医学会外科学分会血管外科学组. 深静脉血栓形成的诊断和治疗指南[J]. 中华普通外科杂志， 2008， 23(3)：235-238.
- 16. ， 31(3)：167-175.
