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find Author "任静" 9 results
  • 曲美他嗪治疗缺血性扩张型心肌病疗效观察

    【摘要】 目的 总结曲美他嗪在缺血性扩张型心肌病患者心功能改善方面的作用。 方法 2007年1月-2009年12月随机将61例患者分为二组,观察组给予常规药物治疗加用曲美他嗪,对照组给予常规治疗,通过心功能及左心室射血分数两个方面来评估治疗效果。 结果 观察组较对照组显著增加左室射血分数,并能改善患者心功能分级。 结论 缺血性扩张型心肌病患者可以很好地耐受较长期的曲美他嗪治疗,同时心功能也得到改善。

    Release date:2016-09-08 09:52 Export PDF Favorites Scan
  • The Anxiety Status and Related Factors of H1N1 Patients at the Influenza Peak of Fever Clinics

    【摘要】 目的 了解甲型H1N1流感发热病区门诊就诊高峰期患者焦虑状况及相关因素,采取针对性护理措施减轻患者焦虑情绪。 方法 2009年11月上旬-12月上旬采用一般资料调查和Zung′s焦虑自评量表(SAS)对219例患者进行调查分析。 结果 219例患者SAS平均分为(33.70±8.60)分,其中17例SAS总分≥50分,存在焦虑情绪,发生率7.76%。多元回归分析结果显示,在年龄、性别、城乡差异、发热程度等因素中,与焦虑症状有关的主要因素为年龄和发热程度。 结论 甲型H1N1流感发热病区门诊就诊高峰期患者焦虑情绪明显高于常模,应引起重视,在门诊工作中加强心理护理,减轻和尽力消除患者的焦虑情绪,以免对病情产生不利影响,不利于控制流感疫情。【Abstract】 Objective To investigate the anxiety status and related factors of H1N1 patients at influenza peak of fever clinics,and to take specific measures to reduce anxiety in patients. Methods The general information and Zung′s self rating anxiety scale (SAS) were taken to analyze 219 patients from early November to early December 2009. Results The average SAS score of the 219 patients was 33.70±8.60, in which there were 17 patients (7.76%) with total scores ≥ 50 and anxiety. Multiple regression analysis showed that the age and temperature were related factors among age, gender, urban-rural differences, and fever. Conclusion The survey suggests that the pafients at the H1N1 influenza peak of fever clinics are significantly more anxious than normal anxiety. Out-patient work should strengthen psychological care to reduce and try to eliminate the anxiety of patients, in order to avoid adverse impact which is not conducive to control influenza outbreaks.

    Release date:2016-09-08 09:52 Export PDF Favorites Scan
  • Structure and preliminary evaluation of Prostate Imaging Reporting and Data System V2 in diagnosis of prostate cancer using multi-parametric MRI

    The incidence of prostate cancer ranks the second in malignant tumors among elderly males. Multi-parametric MRI (Mp-MRI) is an important mean for detection, staging, and grading of prostate cancer. In order to standardize the collection, interpretation, and reporting of prostate MRI data, the European Urogenital Radiology Society launched the Prostate Imaging Reporting and Data System (PI-RADS) in 2012. Due to some limitations in the application process, the Joint Committee of the American Society of Radiology and the European Society of Radiology issued an updated version of PI-PADS V2 in 2014. In recent years, some studies have been carried out on the effectiveness, accuracy, and consistency of the diagnosis of prostate cancer. This article will review the application and research status of PI-RADS V2 system in the diagnosis of Mp-MRI for prostate cancer.

    Release date:2018-04-23 05:00 Export PDF Favorites Scan
  • 多种教学方法结合改善护理本科学生对老年人的态度

    目的探讨理论讲授与模拟老年人体验、赏析老年相关影片等多种教学方法结合对护理本科生对老年人态度的影响。 方法2014年2月-5月选择2011级护理专业学生,在老年护理教学中运用理论讲授结合模拟老年人体验、影片赏析进行教学,在教学前后分别发放中文版Kogan老年态度量表调查学生对老年人的态度,同时分析整理学生的实验报告。 结果学生对老年人的态度评分由培训前的(150.64±13.74)分增加至培训后的(163.13±13.87)分,培训前后差异有统计学意义(P<0.001),其中负向态度以“老年人容易让别人感觉不舒服”、“老年人应该居住于特殊的住所”改善最为明显(P<0.001);实验报告分析78.2%的学生认为老化对老年人影响大,50.1%的学生在实验报告中较全面认识到衰老对老年人的影响。 结论理论讲授与模拟老年人体验、影片赏析等多种教学方法结合有助于改变护理本科学生对老年人的态度和认识。

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  • The Effects of Sleeping-inclued Hypoxema at Different Time and Level on Pulmonary Emphysema and of Coagulation System Function in Rats with Pulmonary Emphysema

    Objective To investigate whether the sleep-induced hypoxemia ( SIH) at different time and different level have different effects on pulmonary emphysema and coagulation systemfunction in the rats with pulmonary emphysema. Methods Thirty Wistar rats were randomly divided into three groups( n = 10 in each group) . All rats were exposed to cigarette smoke twice a day ( 30 min each time) . From29th day on, the rats in Group A ( pulmonary emphysema with short SIH) were also exposed to mixed gas of 12. 5% oxygen for 1. 5 hours during sleeping time every day ( the expose time was divided into 4 periods, 22. 5 min each) . The rats in Group B ( pulmonary emphysema with mild SIH) were also exposed to mixed gas of 15% oxygen for three hours during sleeping time every day( the expose time was divided into 4 periods, 45 min each) . The rats in Group C( pulmonary emphysema with standard SIH) were also exposed to mixed gas of 12. 5% oxygen for three hours during sleeping time every day( the expose time was divided into 4 periods,45 min each) . After continuous exposure for 56 days, the rats were sacrificed. Semi-quantitative image analytic method was employed for histopathological analysis including pathological score of lungs, mean linear intercept ( MLI) and mean alveolus number( MAN) . ATⅢ, FIB, vWF, FⅧ were measured. Results All animals in three groups manifested the histopathological features of emphysema. Pathological scores of lungs and MLI of every group were significantly different from each other( F = 21. 907, F = 18. 415, all P lt; 0. 05) , Group A [ ( 61. 90 ±4. 25) % , ( 92. 45 ±1. 78) μm] and Group B[ ( 64. 60 ±3. 95) % , ( 92. 80 ±3. 65) μm] were significantly lower than Group C[ ( 73. 30 ±3. 86) % , ( 99. 32 ±2. 81) μm, q= 8. 96, q =6. 84, q = 12. 64, q =9. 65, all P lt; 0. 05] . Levels of FIB were significantly different among three groups ( F = 20. 592, P lt; 0. 05) while FIB in Group A[ ( 189. 98 ±5. 29) mg/ dL] and Group B[ ( 182. 70 ±2. 78) mg /dL] were significantly lower than that in Group C[ ( 198. 40 ±7. 37) mg/ dL, q = 4. 86, q= 9. 07, all P lt; 0. 05] , and FIB in Group A was significantly higher than that in Group B( q = 4. 20, P lt; 0. 05) . Levels of FⅧ were significantly different from each other( F = 33. 652, P lt;0. 05) while FⅧ in Group A[ ( 232. 26 ±4. 17) % ]and Group B[ ( 242. 53 ±14. 50) % ] were significantly lower than that in Group C[ ( 303. 25 ±32. 93) % ,q= 10. 73, q = 9. 18, all P lt; 0. 05] . Conclusions Pulmonary emphysema and hypercoagulable states increases with time and severity of SIH in rats with pulmonary emphysema. The elevated activity of blood coagulation factor may be a critical role in the hypercoagulable states.

    Release date:2016-09-14 11:25 Export PDF Favorites Scan
  • The Value of Multi-voxel Proton Magnetic Resonance Spectroscopy Imaging in Assessing the Degree of Glioma Resection

    目的 探讨3D-多体素磁共振波谱(MRS)在评估脑胶质瘤手术切除程度的价值。 方法 对2011年6月-2012年4月32例脑胶质瘤患者术后行常规MRI及MRS检查,测定分析手术周边区域主要代谢产物N-乙酰天门冬氨酸(NAA)、胆碱(Cho)、肌酸(Cr)、Cho/NAA、Cho/Cr及NAA/Cr比值,对术后胶质瘤切除程度进行评价。同时通过术后病理检查结果评估肿瘤切除程度,再与MRS评估结果相比较。 结果 32例中病理评估为9例全切除,23例为大部分切除;MRS评估为11例全切除,21例为大部分切除,评估结果与术后病理评估结果差异无统计学意义(P>0.05)。 结论 MRS可以无创评价胶质瘤切除程度,为胶质瘤预后判定及进一步治疗提供了重要的依据。

    Release date:2016-09-07 02:33 Export PDF Favorites Scan
  • Multidetector CT and Magnetic Resonance Imaging Features of Solitary Fibrous Tumors in the Pelvis and the Relevant Pathologic Basis Changes

    In order to investigate the features of multidetector CT (MDCT) and magnetic resonance imaging (MRI) as well as the corresponding pathogic basis of solitary fibrous tumor (SFT) in the pelvis, we collected the clinical data of 13 patients with pathologically confirmed SFT in pelvis, and retrospectively reviewed the MDCT and MRI appearances. Of these enrolled patients, 6 received MDCT scans, 5 underwent MRI scans, and 2 underwent both MDCT and MRI examinations. Shown on the MDCT and MRI, the maximum diameters of the masses ranged from 4.0 to 25.2 cm (averaged 11.8 cm). Six masses were lobulated, and seven were round or oval. In addition, all masses were well-defined and displaced the adjacent structures to some degrees. On the computed tomography, all masses were of isodensity on unenhanced scans in general, among which five masses were demonstrated with hypodense areas. On the MRI T1-weighted image, all lesions were isointense, of which patchy hypointense areas were detected in 3 cases and radial hypointense areas were in 3 cases, and the other one was presented with homogenous intensity. On T2-weighted images, most of the lesions were mixed hyperintense, of which 3 cases were of heterogenous hyperintesity, radial hypointense areas were detected in 3 patients, and the other one was homogenously intense. On enhanced computed tomography and MRI, large supplying vessels were found in 4 cases; 12 cases showed moderate to conspicuous enhancement, and the other one was presented with mild homogenous enhancement. Of the patients with moderate to conspicuous enhancement, patchy areas of non-enhancement were detected in 7 cases, radial areas of progressive enhancement were detected in 3 cases, and the remained 2 cases showed homogenous enhancement. On pathology, the radial area presented as progressive enhancement was fibrosis. During the follow-ups after surgery, 2 patients had local recurrence and 1 had metastasis to liver. In conclusion, the SFT in the pelvis are commonly presented as a large solid, well-defined and hypervascular mass with necrosis or cystic changes at some extents together with the displacement of adjacent structures. The radial area with hypointensity on T2-weighted image and with progressive enhancement on enhanced magnetic resonance imaging is an important feature of SFT, which can be helpful for the diagnosis of this mass.

    Release date:2021-06-24 10:16 Export PDF Favorites Scan
  • Application of the dynamic contrast enhanced MRI combined with magnetic resonance spectroscopy in diagnosis of prostate cancer

    Objective To investigate the application of the dynamic contrast enhanced MRI (DCE-MRI ) combined with magnetic resonance spectroscopy (MRS) in the diagnosis of prostate cancer. Method A total of 60 patients with prostate cancer and 60 patients with benign prostatic hyperplasia diagnoses in Sichuan Cancer Hospital from January 2011 to January 2014 were included as prostate cancer group and proliferative group respectively. Sixty healthy individuals during the same period were included as the control group. We used Siemens Avanto 1.5 T high field superconducting MRI for DCE-MRI scan and MRS scan. After the MRS scan was finished, we used the workstation spectroscopy tab spectral analysis. Eventually we got the crest lines of prostate metabolites choline (Cho), creatine (Cr) and citrate (Cit). Then we calculated Cho/Cit, (Cho+Cr)/Cit and their average. Results Comparing the signal value in 21 seconds, 1 minute, 2 minutes of DCE-MRI, the differences among the three groups were statistically significant (P<0.05). Comparing the results of spectral analysis, the differences among the three groups were statistically significant (P<0.05). The sensitivity was 89.67%, the specificity was 95.45% and the accuracy was 94.34% when using DCE-MRI combined with MRS. Conclusion DCE-MRI combined with MRS greatly improves the sensitivity, specificity and accuracy of the diagnosis of prostate cancer; it has a great application value in the diagnosis of prostate cancer.

    Release date:2017-07-21 03:43 Export PDF Favorites Scan
  • Application value of gadobutrol in contrast-enhanced magnetic resonance angiography in abdominal artery angiography: a prospective multicenter study

    ObjectiveTo explore the value of gadobutrol enhanced magnetic resonance angiography (MRA) in abdominal artery angiography.MethodsThe patients were prospectively included for gadobutrol enhanced MRA examination from December 2014 to December 2015. The image quality was assessed by two radiologists. The subjective score and signal intensity were measured for the large and medium arteries, and the subjective score for the small artery was recorded. The Kappa consistency analysis was used to assess the two radiologists’ subjective score.ResultsAll 112 patients were enrolled in this study, 96 of whom were included for the physical examination, 16 of whom were included for the liver tumors. No adverse reactions were found in these patients. The MRA images of 2 patients were affected by the severe respiratory artifact. The MRA images of the other 110 cases were clear and could well show the origins, shapes of large and medium arteries and small arteries. The subjective scores were 21.22±1.93 and 6.24±1.33 of the large and medium arteries and small arteries, respectively. The values of signal noise ratio and contrast signal noise ratio of the large and medium arteries were 1 093.27±331.71 and 897.27±333.29, respectively. The Kappa values of the two radiologists’ subjective score were 0.782 and 0.772 for the large and medium arteries and small arteries, respectively.ConclusionsGadobutrol enhanced MRA can clearly display large and medium arteries, and can also display some small arteries. It has a good application value in abdominal artery angiography.

    Release date:2020-06-04 02:30 Export PDF Favorites Scan
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