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find Keyword "低血糖" 12 results
  • The Situation and Causes of Misdiagnosis of Hypoglycemia in China

    Objective To explore the situation and causes of misdiagnosed hypoglycemia in China so as to develop some strategies for reducing misdiagnosis.Methods We searched CBMdisc, CMCC, CJFD and VIP (Jan. 1994-Dec. 2003). All the publisled studies about the misdiagnosis of hypoglycemia were collected to analyse their classifications and causes.Results A total of 172 studies involving 1 478 patients met the inclusion criteria. The studies were either case reports or clinical reviews. The 1 478 cases were misdiagnosed as 31 sorts of diseases, mainly including stroke (71.18%), transient ischemia attack (4.87%), epilepsy (4.13%) and hepatic coma (2.64%) . The causes of misdiagnosis could be classified into 14 categories, including complex manifestations of hypoglycemia (29.07%), lack of knowledge of hypoglycemic encephalopathy (16.44%), insufficient medical history collection (10.21%) and interference of compound diseases (9.86%) etc..Conclusions The misdiagnosis of hypoglycemia is mainly caused by the poor professional skills of doctors or their lack of responsibility, and poor patient management, especially when hypoglycemia are manifested by brain disability.

    Release date:2016-08-25 03:33 Export PDF Favorites Scan
  • 门诊糖尿病患者健康管理在糖尿病治疗中的作用

    摘要:目的:研究糖尿病系统性教育干预对于门诊糖尿病患者血糖控制及其他指标控制的作用。方法:选取血糖控制欠佳或对自己病情控制不满意的100例糖尿病患者为对象,对其进行系统性的健康教育(包括集中授课、个别辅导、派发健康教育小册子、定期回访等),动态观察干预前后患者血糖、血脂、体重指数、低血糖发生率等指标的变化,以及饮食、运动等自我管理的改变,随访6个月。结果:经强化糖尿病教育后,患者自我管理能力提高,血糖血脂控制良好。结论:对门诊糖尿病患者进行强化教育,有助于血糖的控制,延缓糖尿病的发展,减少急慢性并发症的发生。

    Release date:2016-08-26 03:57 Export PDF Favorites Scan
  • Evidence-Based Treatment of Hypoglycemia in A Diabetic Patient with Insulin Autoantibody

    Objective To identify the best therapy regimen for a patient with rare hypoglycemia due to insulin autoantibody (IAA). Methods We searched The Cochrane Library (Issue 3, 2008), PubMed (1966-July 2009), EMbase (1974-July 2009) and CBM (1978-July 2009) to identify relevant evidence. The quality of the retrieved studies was critically assessed. Results A total of 291 records were retrieved. No clinical guidelines, systematic reviews or clinical randomized studies were identified. Thirty treatment-related studies involving 6 interventions showed that insulin combined with Prednisone was relatively more effective and safer than conventional therapies. Conclusion The steroid treatment might be useful for the improvement of glycamic control in patients with high IAA levels and severe hypoglycemia and hyperglycemia due to insulin antibodies raised against subcutaneously-injected human insulin.

    Release date:2016-09-07 11:13 Export PDF Favorites Scan
  • 糖尿病住院患者低血糖发病状况调查

    目的 探讨住院糖尿病患者低血糖发生率、时间分布及类型分布特点,研究低血糖相关危险因素及其干预对策。 方法 2009年5月-11月对199例住院糖尿病患者监测空腹、三餐后2 h及凌晨3时的血糖,了解低血糖类型分布及时间分布特点。 结果 共监测血糖14 276例次,发生低血糖269例次,低血糖发生率1.90%。低血糖时间分布:空腹25例次,早餐后2 h 62例次,午餐前8例次,午餐后2 h 49例次,晚餐前2例次,晚餐后2 h 51例次,凌晨3时72例次。低血糖类型分布:症状性低血糖114例次,无症状性低血糖155例次,发生低血糖时患者血糖值多为2.8~3.9 mmol/L。低血糖治愈率100%。 结论 低血糖时间分布特征以凌晨3时最多,低血糖类型分布特点以无症状低血糖比例最大,早期干预能避免长时间严重低血糖的危害。

    Release date:2016-09-08 09:14 Export PDF Favorites Scan
  • Comprehensive Geriatric Assessment of Patients Older than 75 Years with Type 2 Diabetes Mellitus and A 2-year Follow-up Study of the Effect of Glargin-based Hypoglycemic Therapy

    【摘要】 目的 老年综合评估法筛查75岁以上2型糖尿病(type 2 diabetes mellitus,T2DM)合并老年综合征的情况,并观察以甘精胰岛素为基础的治疗方法对老年综合征、血糖、低血糖事件、治疗满意度等的影响。 方法 应用老年综合评估中的日常生活能力、工具性日程生活能力、简易智能量表、老年抑郁量表、微型营养评定法,分别评估2005年12月—2009年12月老年门诊及病房住院的日常生活能力、认知功能状态、情绪障碍和营养状态,对其合并功能障碍、痴呆、抑郁、营养障碍、伤害性跌倒等老年综合征的患病情况进行横断面调查;筛选至少合并一种老年综合征和一个其他合并疾病,血糖控制差、预期寿命有限的患者进行以甘精胰岛素为基础的降糖治疗,采用自身前后对照的方法了解对糖化血红蛋白(hemoglobin A1c, HbA1c)、低血糖事件、治疗满意度的影响,并观察甘精胰岛素治疗方案对上述老年综合征的影响。 结果 132例老年门诊及病房住院的75岁以上T2DM患者功能障碍者高达50.0%(66例),罹患包括轻度认知功能障碍在内的痴呆比例为39.4%(52例);合并抑郁症28.0%(37例);营养失衡30.0%(39例)。33例患者符合甘精胰岛素治疗纳入标准,经过2年的随访发现,以甘精胰岛素为基础的治疗方案在适当降低HbA1c水平时,不增加老年综合征的患病率,但可以减少胰岛素多次皮下注射的次数,降低低血糖事件发生次数(由1.58次/例降为0.81次/例),提高患者治疗满意度。 结论 75岁以上T2DM患者合并老年综合征的比例高,老年综合评估能及时发现老年综合征;以甘精胰岛素为基础的治疗方案不增加老年综合征的发生,并能显著降低低血糖事件数、改善营养状态、提高患者对治疗的满意度。【Abstract】 Objective To screen geriatric syndrome in patients older than 75 years with type 2 diabetes mellitus (T2DM) by the method of comprehensive geriatric assessment, and observe the impact of glargin-based therapy on geriatric syndrome, blood glucose level, the event of hypoglycemia and treatment satisfaction degree in patients older than 75 years with T2DM who suffered at least one kind of Geriatric syndromes. Methods From December 2005 to December 2009, activity of daily living (ADL), instrument activity of daily living (IADL), mini-mental state examination, geriatric depression scale and mini-nutritional assessment in comprehensive geriatric assessment were used to assess daily living ability, cognitive function status, emotional disorder and nutritional status of out/in-patients older than 75 years with T2DM in the Department of Geriatrics. Cross-sectional study was carried out to investigate geriatric syndromes such as combined functional disorder, dementia, depression, nutritional disorder and impairment falls in those patients, and patients with T2DM combined with at least one kind of geriatric syndrome and another kind of combined disease were screened out. A glargin-based anti-hyperglycemic therapy was carried out for those patients with poor blood glucose control limited remaining life time. The effects of this therapy on hemoglobin A1c (HbA1c), the event of hypoglycemia and treatment satisfaction degree of the patients were studied through a self-comparison method. Then, its effect on the above-mentioned geriatric syndromes was observed. Results Among all the 132 out/in patients older than 75 years with T2DM, the prevalence rates of functional disorder (including ADL and IADL), dementia including mild cognitive disorder, depression, and malnutrition were respectively 50.0% (66), 39.4% (52), 28.0% (37), and 30.0% (39). Only 33 patients met the criteria of glargin-based treatment. After 2 years of follow-up, we found that the glargin-based treatment could properly decrease the level of HbA1c without increasing the prevalence rate of geriatric syndrome. Moreover, it could reduce the frequency of insulin injection and the events of hypoglycemia, and treatment satisfaction degree was also significantly improved. Conclusions Geriatric syndrome has a relatively high prevalence rate in patients older than 75 years with T2DM. Comprehensive geriatric assessment is beneficial in finding out the geriatric syndrome, and glargin-based hypoglycemic therapy can significantly reduce the events of hypoglycemia, improve nutritional status, and increase treatment satisfaction degree without increasing the rate of geriatric syndrome .

    Release date:2016-09-08 09:26 Export PDF Favorites Scan
  • 糖尿病低血糖反应的临床分析

    【摘要】 目的 探讨糖尿病患者强化治疗中的低血糖发生、发展极其后果。 方法 收集2006年1月-2008年12月间58例糖尿病治疗中发生低血糖反应的临床资料进行回顾性分析。 结果 发现糖尿病患者在糖尿病强化治疗中发生低血糖反应,与其胰岛素的使用不规范、患者的糖尿病教育程度有关。 结论 糖尿病强化治疗中应进行有效的糖尿病教育,使其认识到强化治疗对预防慢性并发症的益处,也要了解低血糖反应的危害,同时要掌握自救方法,避免低血糖反应的严重并发症发生。

    Release date:2016-09-08 09:51 Export PDF Favorites Scan
  • Diagnosis and Treatment of Hepatocellular Carcinoma with Hypoglycemia

    目的 探讨肝癌合并低血糖的诊断及治疗。方法 对中国医科大学附属第四医院2010年1月至2013年4月期间收治的27例肝癌伴低血糖患者的临床资料进行回顾性分析。结果 27例患者中转移性肝癌2例,原发性肝癌25例;其中伴肝硬变9例。所有患者均给予护肝、补充能量治疗;22例行手术治疗后血糖全部控制在正常或仅轻度升高,5例因肿瘤无法切除而放弃手术治疗,其中1例伴肝硬变肝癌患者2个月后再次低血糖症状发作后死亡。结论 低血糖是肝癌少见的并发症,早期诊断及治疗有助于避免后遗症的发生并改善预后。

    Release date:2016-09-08 10:24 Export PDF Favorites Scan
  • Current Status of the Knowledge of Hypoglycemia and Analysis of Its Influencing Factors in Patients with Type 2 Diabetes Mellitus in China

    ObjectiveTo investigate the knowledge of hypoglycemia in patients with type 2 diabetes mellitus, analyze its influential factors, and explore the measure of hypoglycemia education. MethodsA questionnaire survey was conducted with a sample of 5 961 patients with type 2 diabetes mellitus from 144 hospitals in China between April and July 2010. The investigation contents included patients' demographic data and the knowledge of hypoglycemia. ResultsThe score of the knowledge of hypoglycemia was 62.71±10.34 and the status was medium. Multiple stepwise regression analysis showed that degree of education, duration of diabetes mellitus, periodic inspection, education about diabetic complications, times of hypoglycemia were influencing factors for the knowledge of hypoglycemia (P<0.05). ConclusionThe status of the knowledge of hypoglycemia is not optimistic. Educators should pay attention to the characteristics of patients and provide a safe regiment for controlling blood sugar with a comprehensive introduction of hypoglycemia.

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  • 胰腺动脉钙刺激静脉采血术在一例低血糖症患者诊治中的应用

    Release date:2017-02-22 03:47 Export PDF Favorites Scan
  • Clinical analysis of diabetes related seizures

    ObjectiveTo investigate the clinical symptom and risk factors of diabetic seizures. MethodsThe clinical data of 44 patients with diabetes related seizures were analyzed with the clinical classification, blood glucose, Na+, Plasma Osmotic Pressure, HbA1c, EEG, brain MR, and the antiepileptic drugs. Results① Diabetic hyperglycemia (DH) related seizures: among the 28 patients, 17 cases were male patients, 11 cases were female patients. The mean age was 51.3 years old. Simple partial seizure without secondary generalized seizures (12/28, 42.8%) was the most common, 8 patients (8/28, 28.6%) showed complex partial seizure, 8 patients (8/28, 28.6%) showed no obvious focal origin generalized tonic-closure seizures. Patients with poor glycemic control (HbA1c > 9%) had significantly higher risk of generalized seizures (46.7% vs. 7.7 %, P < 0.05) (P < 0.05). ② Diabetic ketoa-cidosis or hypertonic state associated seizures: among the 7 patients, 6 cases were male patients, 1case was female patients. The mean age was 45.7 years old, 2 patients (2/7, 28.6%) had generalized tonic-clonic seizure, 2 patients (2/7, 28.6%) showed status epilepticus, 2 patients (2/7, 28.6%) showed local motor seizure, 1 patient (1/7, 14.2%) showed Jackson seizure. ③ Diabetic hypoglycemia related seizures: among the 9 patients, 7 cases were male patients, 2 cases were female patients. The mean age was 45.3 years old.5 patients showed generalized tonic-clonic seizure (5/9, 55.6%), 3 patients had complex partial seizure (3/9, 33.3%), 1 patients had generalized tonic-closure seizures (1/9, 11.1%). ConclusionSimple partial seizure is the most common in patients with diabetic hyperglycemia related seizures; so as to diabetic hypoglycemia and keto-acidosis, generalized seizures are relatively common. HbA1c can be an important risk factor of seizures for patients with hyperglycemia.

    Release date:2017-04-01 08:51 Export PDF Favorites Scan
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