目的 探讨持续性非卧床腹膜透析（CAPD）患者低钾血症的发生及临床特点。 方法 选取2002年12月－2011年12月采取持续非卧床腹膜透析治疗的47例尿毒症患者，就其透析过程中低钾血症发生情况进行总结分析。 结果 低钾血症31例（66%）；低钾血症组与非低钾血症组比较，低钾血症组血尿素氮、肌酐、血钠、血氯、血钙及白蛋白明显降低（P＜0.05）；两组年龄、性别、糖尿病肾病所占的比例及透析龄差异均无统计学意义（P＞0.05）。血钾水平随白蛋白浓度、血氯及血钙的提高而下降（OR=0.756， 0.772，0.022，P＜0.05）。 结论 密切联系、定期随诊观察CAPD患者，提高患者就诊依从性，及时发现与纠正低钾血症，有助于提高CAPD患者的生活质量与长期存活率。
【摘要】 患者为老年男性,反复出现恶心、呕吐、乏力、低钠、低钾血症, 3次住院。对其恶心呕吐原因,曾考虑是否有抗高血压药物吲哒帕胺所引起,或是老年人摄入不足,电解质紊乱所致低钠低钾血症。最后考虑该患者低钠血症系垂体前叶功能减退所致。MRI检查显示空蝶鞍。空鞍的原因尚不清楚,空鞍综合征也是垂体前叶功能减退的因素之一。此症尽管很少见,但随着CT、MRI这些高新设备的普遍使用及人口老龄化,会发现更多的病例,也对我们诊断治疗提供了有力的依据。【Abstract】The patient’s condition: old male patient with repeat nausea, vomitus, hypodynamia, low sodium and kaliopenia. Three times to be in hospital. First, we consider that indapamide resuted low sodium and Kaliopemia,but we discovered that the anterior pituitay gland hypofunction. MRI show that empty sella turcica. The reason of empty is not clear,the saddle syndrome is also a factor of pituitary function before the leaves falling off. The disease was rare,but with common use of CT,MRI and aging,we will discover many more cases to provide power evidence for diagnosis and treatment.
Objective To evaluate the safety and efficacy of potassium and magnesium supplement with potassium aspartate and magnesium aspartate injection in gastrointestinal surgery patients during absolute fasting．Methods A multicenter randomized controlled clinical trial was conducted in 111 patients after gastrointestinal surgery. For trial group，56 patients were given potassium aspartate and magnesium aspartate injection （Panangin®） in half of the total potassium replenished dose and the rest half of the potassium replenished dose was given in 10% potassium chloride injection．For control group，55 patients were given 10% potassium chloride injection for the total dose of potassium replenished．Such treatments maintained five consecutive days after surgical operation．Clinical observations were performed until patients were discharged from the hospitals．Results Before the intervention，there were no significant differences for the baseline between two groups （P＞0.05）．There was no significant difference for the serum potassium level between two groups （P＞0.05） after intervention．The amount of urinary potassium （mmol/24 h） for patients in the trial group was significantly lower than that in the control group during treatment after operation．The serum magnesium level of control group was much lower than that of control group （P＜0.05）. In the clinical observation process，no drug-related adverse event was observed．Conclusions The supplementary effect of potassium and magnesium for potassium aspartate and magnesium aspartate injection in patients with gastrointestinal surgery during absolute fasting is significant，and superior to potassium chloride injection for potassium supplement．Potassium aspartate and magnesium aspartate injection is a safe and appropriate choice for patients with potassium depletion．