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find Author "冯海娟" 2 results
  • 库存悬浮红细胞预处理对婴幼儿预充液中血糖、乳酸及钾离子的影响

    目的 观察库存悬浮红细胞预处理后对婴幼儿预充液中血糖、乳酸及钾离子浓度的影响,及对婴幼儿生理代谢的影响。 方法 2010年2月至2011年3月解放军第452医院收治40例先天性心脏病婴幼儿,按预充前是否清洗库存悬浮红细胞,将其分为两组,悬浮红细胞清洗组(清洗组,n=20):男11例,女9例;年龄(17.82±6.11)个月;在体外循环(CPB)中预充前采用血液回收机(cell saver)对库存悬浮红细胞进行清洗预处理;未清洗组(n=20):男6例,女14例;年龄(16.63±4.45)个月;在应用库存悬浮红细胞预充前未经清洗。两组在预充前(清洗组在库存悬浮红细胞清洗前、清洗后)、预充后、CPB前并行期、主动脉阻断后5 min、停机时分别检测血糖、血清乳酸和血钾离子浓度。 结果 清洗组库存悬浮红细胞清洗后血糖、乳酸和钾离子浓度明显低于清洗前(P<0.05)。在CPB各时间点清洗组血糖[主动脉阻断后5 min: (4.50±0.65) mmol/L vs. (5.78±0.62) mmol/L,t=5.308,P=0.001]和乳酸浓度 [主动脉阻断后5 min:(1.86±0.21) mmol/L vs. (2.89±0.45) mmol/L,t=1.504,P=0.001]明显低于未清洗组。除停机时,其余时间点清洗组钾离子浓度明显低于未清洗组 [主动脉阻断后5 min: (3.81±0.32) mmol/L vs. (4.44±0.51) mmol/L,t=3.588,P=0.011]。 结论 采用血液回收机(cell saver)清洗后的含库存悬浮红细胞预充液中的血糖、乳酸、钾离子浓度明显降低至生理范围内,可显著提高婴幼儿CPB的安全性。

    Release date:2016-08-30 05:45 Export PDF Favorites Scan
  • Neonatal Resuscitation Technique in Reducing Neonatal Asphyxia Rate and Mortality Rate in China: A Systematic Review

    ObjectiveTo systematically review the efficacy of promoting neonatal resuscitation technique in treatment of neonatal asphyxia in China. MethodsElectronical databases including WanFang Data, CNKI, VIP, Jiangsu Engineering and Technology Literature Information Center, PubMed and The Cochrane Library (Issue 5, 2016) were searched to collect studies of neonatal resuscitation technique in treatment of neonatal asphyxia up to June 1st, 2016. Two reviewers independently screened literature, extracted data and assessed the risk bias of included studies, and then meta-analysis was performed by using RevMan 5.2 software. ResultsA total of eighteen observational studies were included, involving 28 144 cases of neonatal asphyxia and 32 636 cases of control, 2 148 death cases of neonatal asphyxia and 1 679 cases of controls. The results of meta-analysis showed that neonatal resuscitation technique could reduce newborn suffocation rate compared with the control group in hospital surveys (RR=0.59, 95%CI 0.55 to 0.63, P<0.000 01) and in regional project surveys (RR=0.72, 95%CI 0.69 to 0.75, P<0.000 01). Neonatal resuscitation could also reduce neonatal asphyxia mortality rate in hospital surveys (RR=0.26, 95%CI 0.16 to 0.42, P<0.000 01) and in regional surveys (RR=0.65, 95%CI 0.55 to 0.77, P<0.000 01). ConclusionThe existing evidence shows that neonatal resuscitation technology could effectively reduce the incidence of neonatal asphyxia and mortality rate in China. Due to the limitations of the quantity and quality of present studies, we need to carry out prospective multicenter cohort studies to verify the current results.

    Release date:2016-12-21 03:39 Export PDF Favorites Scan
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