睡眠呼吸暂停低通气综合征( SAHS) 是一种常见病症,临床上以阻塞性睡眠呼吸暂停低通气综合征( OSAHS) 最为常见[1] 。1993 年一项基于社区人群的研究中, Young 等[2] 发现年龄介于30 ~60 岁的人群中, 以睡眠呼吸暂停低通气指数( AHI) ≥5 次/h 定义的OSAHS在女性的患病率为9% ,在男性为24% , 2% 的女性和4% 的男性同时存在嗜睡症状。越来越多的证据表明睡眠呼吸暂停可导致许多并发症, 包括行为和躯体两方面。行为并发症包括日间嗜睡、注意力下降和神经心理异常, 而躯体并发症主要包括心脑血管疾病, 尤其是高血压[3, 4] 。OSAHS 是全身多个脏器功能损害的独立危险因素, 其中心血管并发症是主要死因[5] 。如何评价OSAHS 病情严重程度, 对患者的诊断、治疗及预后判断具有非常重要的意义。目前AHI 仍然是诊断OSAHS 的金标准,但其与靶器官损害的相关性存在诸多争议。
目的 观察独用内镜下手术以及联合等离子低温射频治疗外耳道乳头状瘤的疗效。 方法 2006年7月-2010年7月,随机将收治的45例外耳道乳头状瘤患者(150只耳)分组,比较独用内镜下手术组(A组)以及联合等离子低温射频组(B组)治疗外耳道乳头状瘤的疗效。 结果 患者均术后成功随访1~3年,48只患耳无复发及恶变,2只患耳3个月后复发。 结论 内镜下手术联合等离子低温射频治疗外耳道乳头状瘤具有微创,手术彻底有效,防止复发的优点,值得临床广泛应用。
目的:分析汶川地震致脊髓损伤患者的病情特点。方法:对35例地震致脊髓损伤患者进行回顾性调查。结果:地震造成的这35例脊髓损伤患者在性别、年龄无明显差异,完全性损伤占42.86%,不完全损伤占57.14%。主要致伤原因为压榨伤(68.57%)。骨折部位依次为腰椎(57.14%)、胸椎(28.57%)、颈椎(11.43%)。受伤时体位60%为屈曲位。31.43%的完全性损伤患者由非专业救援人员救出。结论:35例患者脊髓损伤程度普遍较重,主要是与地震当时巨大冲击力有关,也与受灾现场救援条件严重受限,错过最佳治疗时机有关。现场的急救、救援方式对患者的伤情和预后有重要影响,因此需要大力宣传和普及灾害后抢救伤员的基本知识。
目的:探讨5·12汶川地震致脊髓损伤患者神经源膀胱的康复治疗方法。方法:通过对35例脊髓损伤患者神经源膀胱康复治疗的总结回顾,观察采用制定饮水计划,间歇性导尿,药物治疗,膀胱功能训练,手术治疗等方法治疗神经源膀胱的疗效。结果:经过综合治疗,35例患者的神经源膀胱都得到了不同程度的改善。结论:地震致脊髓损伤发生率高,而神经源膀胱是其重大并发症之一,危害患者生命,重建脊髓损伤后患者的膀胱功能对于提高截瘫患者的生活质量,降低死亡率具有十分重要的意义。
ObjectiveTo compare the clinical effects of pulsed electromagnetic fields (PEMFs) with oral alendronate in the treatment of postmenopausal osteoporosis. MethodsFourty patients diagnosed to have postmenopausal osteoporosis (OP) from September 2009 to September 2010 were included in our study. They were randomly divided into the experimental group and the control group. All patients were administered the same basic drugs:Caltrate 600 mg and Alfacalcidol 0.5 μg per day. For the experimental group, PEMFs were offered 6 times per week for 5 weeks (30 times in total), and patients in this group were followed up for 12 weeks. For the control group, alendronate was given at a dose of 70 mg per week for 12 weeks. Bone mineral density (BMD), visual analogue scale, and manual muscle testing (MMT) scale were evaluated before, 1 week, 5 weeks, and 12 weeks after intervention. ResultsIncreasing of BMD, pain relieving, and improvement of MMT had a trend of increasing values after 5 weeks of treatment in the experimental group (P<0.05), but there was no significant difference between the two groups (P>0.05). However, there was a significant difference between the two groups in patients' lower back muscle strength after treatment (P<0.05). ConclusionPEMFs have the same effect as alendronate in pain relief, and bone mass and muscle strength improvement, and are even advantageous in increasing back muscle strength compared with alendronate.
The early damage detection and evaluation are of great significance in treatment and prognosis to the left ventricular function for children with tumor. In this paper, it is reported that the early damage of the left ventricular function was observed by pulsed wave Doppler (PWD) and tissue Doppler imaging (TDI) in our laboratory. Eighty children half a year to fourteen years old were included in this study. The cardiac function indices in chemotherapy group and control group were measured and compared. The results showed that there was significant difference in mitral and tricuspid annulus flow spectrum between the two groups. Compared with PWD, TDI is more prompt, objective and accurate in detecting early damage of left ventricular function in children with tumor.And TDI is a good method for early identification of ventricular function damage in children with tumor.
Computational fluid dynamics was used to investigate the effect of the pathogenesis of membranous obstruction of inferior vena cava of Budd-Chiari syndrome with various angles between right hepatic vein and inferior vena cava. Mimics software was used to reconstruct the models from magnetic resonance imaging (MRI) angiograms of inferior vena cava, right hepatic vein, middle hepatic vein and left hepatic vein, and 3DMAX was used to construct the models of 30°, 60°, 90° and 120° angles between right hepatic vein and inferior vena cava, which was based on the reconstructed models.The model was conducted with clinical parameters in terms of wall shear stress distribution, static pressure distribution and blood velocity. The results demonstrated that the differences between wall shear stress and static pressure had statistical significance with various angles between right hepatic vein and inferior vena cava by SPSS. The pathogenesis of membranous obstruction of inferior vena cava had a correlation with the angles between right hepatic vein and inferior vena cava.