Objective To study the etiology of primary intrahepatic stones. MethodsThe literatures in the recent years on the etiology of intrahepatic stone were revieved. Results The formation of intrahepatic stone mainly caused by bacteria infection, parasitic infestation, bile stasis, congenital anatomic abnormalities and immunoreaction of bile tract. Further investigation found that metabolic, low protein diet, environment and ethnic factors and gene mutation were considered to play important roles in the formation of the intrahepatic stone. Conclusion The formation of intrahepatic stone is complex and are result of multiple factors. It closely related to the infection and stasis of the bile duct.
【摘要】目的探讨肝切除术治疗原发性肝细胞癌自发性破裂（SRHCC）的效果。方法回顾性分析19例肝切除术治疗SRHCC患者的效果。结果肝切除19例，1个月存活率为94.7%，1年、3年及5年存活率分别为63.2%、16.7%及8.3%,平均存活时间为30.8个月(4 d～25年零9个月)，最长1例存活超过25年零9个月，目前仍健在。１８例肝功能属ChildPugh A级患者安全度过围手术期； 1例肝功能ChildPugh B级者术后4 d死于肝功能衰竭。结论SRHCC并非均为晚期病变，对早期肝癌破裂肝功能良好者应采取急诊手术切肝； 如患者情况或医疗条件不允许，可行延期或二期手术治疗。