1概述1.1梗阻性黄疸的原因根据大量临床资料统计,引发梗阻性黄疸最常见的原因是胆总管结石、胰头癌、肝门恶性淋巴结长大; 其次是壶腹部癌、胰腺炎、肝继发性病变; 少见的原因有良性狭窄(医源性、创伤)、复发性胆管炎、Mirizzi’s综合征、硬化性胆管炎、胆管癌、胆道闭锁和胆总管囊肿。
自20世纪60年代中期,发现仅从静脉给予机体所必需的营养物质,就可以维持幼体动物的生存发育与成长以来,古老的营养支持疗法开始了一个新的辉煌时期。经过近30多年的研究与实践,其内涵得到更大的发展,80年代以后,营养支持在我国普外临床也有较快的进展,当前已成为临床重要的治疗手段。在提高危重患者的治愈率,降低外科手术后并发症,加速术后患者的恢复和减少住院时间起到了很重要的作用,无论在营养支持的基础理论或临床实践都有了更深入的认识。因此,它的应用范围在不断地扩大,其临床地位也日益显得重要。
Objective To evaluate whether to defer abdomen surgery in patients having poorly controlled or untreated hypertension before operation. MethodsThe perioperative clinical data of 531 patients with hypertension in our hospital from January 1997 to December 1998 was retrospectively analyzed. ResultsThe modility of perioperative hypertensive events was not significantly different, between controlled and uncontrolled patients with grade one and grade two(Pgt;0.05). In grade three and systolic hypertension, certain complications in patients with poorly controlled hypertension were higher than in those with wellcontrolled hypertension(P<0.05). Conclusion The patients with grade one and grade two hypertension are not at increased operative risk. In patients with grade three and systolic hypertension, perioperative complications are increased and elective surgery should be postponed until their blood pressure is brought under 24/14.7 kPa (180/110 mm Hg) over 1 to 2 weeks.
Objective To enhance survival rate and treatment effect for advanced gallbladder cancer (GBC). MethodsEighty cases of advanced GBC were treated surgically from January 1990 to June 2001.Seventyone cases had obstructive jaundice, 15 had palpable abdominal mass. Extended radical cholecystectomy was performed in 39 cases of advanced GBC in which the tumor invaded the surrounding organs or tissues but without distant metastasis. ResultsFollowup showed that the survival period was between 8 and 37 months (average 18.1 months), 1, 2 and 3year survival rates were 43.6%, 20.5% and 5.1% respectively. Palliative operations were performed in other 41 advanced GBC cases with distant metastasis. All of the patients died within one year. Conclusion This result suggests that extended radical cholecystectomy is effective for advanced GBC.
目的 探讨胆石性肠梗阻的诊断与治疗方案。方法 对我科1990~1999年诊治的11例胆石性肠梗阻的临床表现、治疗结果、术前诊断及手术时机与术式选择进行回顾性分析。结果 11例患者均痊愈出院。其中1例患者发生急性肾功衰竭,2例患者切口感染。3例未做十二指肠瘘口处理的患者有2例在半年后行胆囊切除十二指肠瘘口修补治愈。结论 根据患者全身情况选择不同的手术方式均可取得满意的效果。
【Abstract】Objective To search for the drug that promots the hepatocyte regeneration after partial hepatectomy. Methods Quantitative morphometry technique, 3H-TdR in vivo test and arterial ketone body ratio (AKBR) were employed to evaluate the energy metabolism, DNA synthesis, and liver cell nuclear mitosis and hepatocyte regeneration of the residual liver tissue in rats after partial lobectomy when treated with human growth hormone (hGH) and placebo. Results After partial hepatectomy in the experimental group, liver cell nuclear mitosis,nuclear density, new liver cell numbers, AKBR and 3H-TdR in vivo test were much higher than those in the control group (P<0.01 or P<0.05). Conclusion hGH promotes the hepatocyte regeneration of the residual liver.