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find Keyword "异位甲状腺" 3 results
  • Analysis on Diagnosis and Treatment of 14 Cases of Ectopic Thyroid Gland Disease

    ObjectiveTo explore the clinical characteristics, diagnosis and treatment of ectopic thyroid gland (ETG) so as to reduce the misdiagnosis and improper treatment. MethodsAccording to the patients who were definitely diagnosed ETG by pathology from 2002 to 2010 in our hospital, their clinical and pathological data were retrospectively analyzed. ResultsThere were 14 patients, 4 cases of male and 10 cases of female. Five patients had clinical symptoms. Eight cases were diagnosed before operation and six cases were diagnosed by pathology after operation. There were 4 cases were malignancy and 10 were benign. Three cases of differentiated ectopic thyroid carcinoma patients and 1 normal position's thyroid had papillary carcinoma patient accepted TSH suppression treatment after operation, 4 benign patients and 1 ectopic thyroid medullary carcinoma patient accepted levothyroxine substitution treatment after operation, and the other 5 benign patients did not accept any treatment after operation. Nine patients who accepted follow-up in 1-10 years had orthobiosis, and the malignancy patients without recurrence and metastasis. ConclusionsETG usually reveal no any special clinical features. For any masses from root of tongue to mediastinum, especially cervical masses, should be carefully check whether there are thyroid in normal position, and to exclude ETG. The color Doppler ultrasound, thyroid radioactive scanning, thyroid function tests, computed tomography, and fine needle aspiration cytology are all important examination measures. Due to the ETG may occur the same lesions as the normal position's thyroid, so once it is be definitly diagnosed, the treatment should be based on patient's age, position, size, and type of ETG, and nature of the lesions to select follow-up observation, operative treatment, levothyroxine replacement or therapeutic inhibition of TSH, and 131I therapy.

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  • Mediastinal ectopic papillary thyroid carcinoma: A case report

    We report a 50-year-old man with mediastinal tumor. The patient received the thoracoscopic resection for mediastinal tumor with the operative time of 1 h and intraoperative blood loss of 10 mL. The final diagnosis after surgical excision was an ectopic papillary thyroid carcinoma. The patient recovered well without surgery-related complications, and was discharged on the 2nd day after the operation. No recurrence was found during the follow-up. We also reviewed relevant literature to explore the clinical features, diagnosis, and treatment of ectopic thyroid carcinoma.

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  • 可疑肾上腺内异位甲状腺1例报道并文献复习

    目的总结肾上腺内异位甲状腺的影像学表现、病理特征、临床诊断、鉴别诊断以及治疗方法和预后。方法回顾性分析2023年3月广东医科大学附属医院收治的1例可疑肾上腺内异位甲状腺的临床表现、病理特征、治疗及预后情况,并结合国内外相关文献报道的26例肾上腺内异位甲状腺的病例资料进行分析。结果本例66岁女性患者,术前检查提示左侧肾上腺占位(考虑嗜铬细胞瘤)并行手术完整切除,术后根据病理学检查和免疫组织化学检查最终考虑诊断为肾上腺内异位甲状腺并腺瘤样增生,术后随访6个月未见复发。复习国内外文献报道的26例肾上腺内异位甲状腺患者资料,亚洲中老年女性多见(22例),左侧多发(17例),大部分(19例)由体检发现,通常表现为无痛性囊性肿块,大体呈类圆形,镜下可见甲状腺样组织,并见甲状腺样滤泡,滤泡腔内见嗜酸性胶质样物,部分区域可见滤泡与肾上腺皮质混杂,通常无肾上腺髓质成分,囊壁被覆扁平上皮细胞或甲状腺滤泡样细胞、可见核重叠,偶见核沟和包涵体,类似甲状腺乳头状癌细胞核,但未见砂粒体。免疫组织化学表现为PCK、EMA、TTF-1、Tg、Vimentin阳性,提示甲状腺分化,BRAFV600E、KRAS基因突变阴性。治疗以完整切除肿瘤为主,预后良好。结论肾上腺内异位甲状腺罕见,确切发生机制有待研究,临床术前不易辨识,应与肾上腺肿瘤、转移性甲状腺滤泡癌、乳头状癌等鉴别,免疫组织化学染色及基因检测有助于明确诊断,治疗以完整切除肿瘤为主,预后良好。

    Release date:2024-05-28 01:54 Export PDF Favorites Scan
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