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find Author "肖亦敏" 3 results
  • Clinical Analysis of 1405 Patients Undergoing Coronary Artery Bypass Grafting and Transmyocardial Laser Revascularization

    Objective To summarize the essential of perioperative therapy and improve the prognosis of coronary artery bypass grafting (CABG) and transmyocardial laser revascularization (TMLR) through analyzing 1405 patients with coronary atherosclerotic heart disease. Methods From May 1997 to January 2006, 1 405 patients were treated in our hospital. On-pump CABG were performed in 825 patients, single CABG were performed in 666 patients, CABG with cardiac valvular operation in 98 patients, CABG with cardiac ventricular aneurysm resection in 55 patients, CABG with ventricular septal defect repairment in 2 patients; CABG with left atrium gelatinous tumor resection in 2 patients, CABG with ascending aorta repairment in 1 patient, and mediastinal septum tumor resection in 1 patient. Off-pump coronary artery bypass grafting (OPCAB) were performed in 500 patients; single TMLR were performed in 30 patients, CABG+TMLR were performed in 50 patients. Results The number of bridge vessel was 2.9±1.0. Forty-two patients(3.0%) died of bleeding, myocardial infarction, low cardiac output syndrome, renal failure, multiple organ failure(MOF) and so on. Various complications were occurred in 70 patients(5.0%), including bleeding, low cardiac output syndrome, myocardial infarction, renal failure and so on. All of them were recovered after treatment. There were 1 177 patients of angina in grade Ⅲ-Ⅳ (CCS) before operation, 1 154 of them (98.0%) changed in grade 0-Ⅰ (CCS) postoperatively. There were 857 patients (62.9%) in follow-up for 8.3±2.9 months postoperatively. There was no angina in 788 patients(91.9%) 6 months after surgery. The ultrasonic graphic showed that left ventricular ejection fraction was 0.66±0.10 and raised 7.9% than that before operation. The quality of life was better than before. Conclusion CABG has become the most potent routine operation in the therapy of coronary artery disease. It can extend the applications of CABG and improve the operative prognosis, if the indications are correctly mastered and the perioperative management are enhanced.

    Release date:2016-08-30 06:23 Export PDF Favorites Scan
  • Surgical Treatment for Patients with Stanford Type A Aortic Dissection

    ObjectiveTo summarize our clinical experience of surgical treatment for 51 patients with Stanford type A aortic dissection (AD). MethodsClinical data of 51 patients with Stanford type A AD who received surgical treatment in Shanghai Yuanda Heart Hospital between February 2009 and January 2013 were retrospectively analyzed. There were 29 males and 22 females with their age of 35-63 (47.2±11.1)years. The diagnosis of all the patients was confirmed by enhanced CT scan and Doppler echocardiography. Surgical procedures included Bentall procedure and Sun's procedure in 29 patients, Bentall procedure, mitral valve replacement and Sun's procedure in 2 patients, ascending aorta replacement and Sun's procedure in 17 patients, valsalva sinus plasty, ascending aorta replacement and Sun's procedure in 2 patients, ascending aorta replacement (stage 1), Sun's procedure (stage 2)and endovascular exclusion of the thoracic aorta (stage 3)in 1 patient. ResultsMean operation time was 320.6±77.3 minutes, cardiopulmonary bypass time was 190.4±63.4 minutes, aortic cross-clamp time was 123.2±45.1 minutes, duration of circulatory arrest with hypothermia was 28.2±11.1 minutes, and mean length of hospital stay was 13.4±4.2 days. Two patients (3.9%)died perioperatively including 1 patient with intraoperative bleeding and another patient with delayed bleeding after operation. Postoperative complications included bleeding, paraplegia, perivalvular leak and sternal dehiscence in 1 patient respectively, and endoleak in 2 patients. Forty-nine patients were followed up for 3-48 (25.3±10.5)months and no late death occurred. ConclusionSurgical treatment is effective for patients with Stanford type A AD.

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  • 心脏机械瓣膜置换术后华法林低强度抗凝治疗的临床分析

    目的评价心脏机械瓣膜置换术后华法林抗凝治疗低强度国际标准化比值(INR)的有效性及安全性。 方法纳入2010年9月至2012年9月上海远大心胸医院行人工机械瓣膜置换术后行华法林抗凝的患者212例,按INR值分为低强度抗凝组(A组)98例,其中男50例、女48例,平均年龄(58.4±6.5)岁。INR在1.5~2.0;标准抗凝组(B组)114例,其中男58例、女56例,平均年龄(57.3±5.1)岁。INR维持在2.0~3.0。 结果两组均无血栓形成并发症发生。A组无出血。B组总体出血不良反应发生5例(发生率4.39%),其中牙龈出血3例(发生率2.63%),鼻出血1例(发生率0.88%),消化道出血1例(发生率0.88%)。两组出血发生率差异有统计学意义(0% vs.4.39%,P<0.05)。 结论心脏机械瓣膜置换术后,华法林抗凝治疗维持INR在1.5~2.0之间是安全有效的,不增加出血及血栓形成的风险。

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