目的 分析眼表面肿块的发病情况及组织病理学特点。 方法 对2004年1月-2008年12月收治并经病理学证实的326例眼表面肿块患者的年龄、性别、眼别、肿块发生部位、肿块性质及病理类型进行回顾性分析。 结果 326例眼表面肿块中，良性肿块264例（81.0%），恶性肿块62例（19.0%）。良性肿块中，前5位分别为色素痣67例（25.4）%，迷芽瘤63例（23.9）%，乳头状瘤39例（占14.8）%，结膜囊肿25例（9.5）%，炎性肉芽肿20例（7.6）%。恶性肿块中，前4位分别为鳞状细胞癌25例（40.3）%，淋巴瘤13例（21.0）%，恶性黑色素瘤12例（19.4）%，原位癌10例（16.1）%。 结论 眼球表面的肿块有共同的组织细胞起源，肿块的亚型表现出不同的组织结构、良恶性和好发部位；而同部位的良性、交界性和恶性病变的衍变发展，从某种程度上体现了一个疾病的不同发展阶段，三者间的鉴别和明确的病理诊断能为临床选择手术时机及手术方式提供依据。
ObjectiveTo observe the imaging features of optical coherence tomography (OCT) in peripheral retinal abnormalities of high myopia (HM). MethodsA retrospective series of case studies were conducted. From March 2019 to March 2021, 38 cases (50 eyes) in high myopia with peripheral retinal abnormalities who were confirmed to Henan Eye Hospital were enrolled in the study. There were 21 eyes in 17 males and 29 eyes in 21 females, age was 39.58±15.29 years, diopter was (－9.10±2.44) D. All patients underwent wide-angle fundus photography and OCT examination. According to wide-angle fundus photography and OCT, HM with peripheral retinal abnormalities were classified into white-without-pressure, black-without-pressure, lattice degeneration, peripheral pigmented degeneration, retinoschisis and retinal holes. OCT imaging features of peripheral abnormalities in high myopia was observed. ResultsIn 50 eyes, 65 peripheral retinal abnormalities were observed by OCT. In 6 white-without-pressure, intense hyperreflectivity was shown at the level of the ellipsoid zone that abruptly transitions to relative hyporeflectivity at the dark border of the lesion. In 16 black-without-pressure, reflectivity of the ellipsoid zone decreased. In 10 sites of lattice degeneration, cystoid degeneration, local thinning, retinal tear at the posterior edge and boundary of the lesion was shown, whcih may be accompanied by local vitreous condensation and traction. In 4 peripheral pigmented degeneration, retinal interlayer hyperreflectivity was shown. In 12 retinoschisis, neuroepith-elial separation was connected by vertical bridge or columnar light bands, of which 3 were accompanied with localized retinal detachment and 2 with splitting-related retinal vascular abnormalities. In 17 retinal holes, full layer of neuroepithelium lost, that 12 zones were accompanied with retinal detachment with vitreous adhesion or traction. ConclusionOCT manifestations of peripheral retinal abnormalities in HM varies.