Objective To evaluate quality of orthopedic clinical practice guidelines in China by AGREE Ⅱ Instrument. Methods A systematic search of relevant literature databases (CBM, WanFang Data, VIP and CNKI) was conducted to identify the orthopedic clinical practice guidelines of China published up to October 2016. Guidelines selection and data extraction were independently performed by two authors. AGREEⅡ instrument was used to evaluate the quality of the included guidelines. Intra-class correlation coefficient tests were performed to appraise the uniformity of the overall assessment scores. Results A total of 54 guidelines for orthopedics were finally included. The mean scores of six domains by AGREE Ⅱ instrument were 60.44%, 21.40%, 5.17%, 22.17%, 6.02% and 0.56%. The overall intra-class correlation coefficient was 0.84. Conclusion The quality of orthopedic clinical practice guidelines in China was low or moderate in general. The methodology of making guidelines, especially in terms of rigor of development, applicability and editorial independence, should be improved.
In order to develop the clinical practice guideline (CPG) of intra-articular injection for knee osteoarthritis, based on the definition of Institution of Medicine (IOM) about CPG, the WHO handbook, the GRADE instrument, the AGREE Ⅱinstrument, and the Right for Reporting CPG, Chinese Orthopaedic Association,Chinese Journal of Orthopaedics, Arthritis Clinic and Research Center of Peking University People’s Hospital, Chinese GRADE Center established the guideline working groups and develop protocol of the guideline.
ObjectivesTo systematically review the prevalence and disease burden of knee osteoarthritis (KOA) in China.MethodsPubMed, EMbase, CNKI, WanFang Data and VIP databases were searched to collect cross-sectional studies about the prevalence and disease burden of KOA in China from January 1st 1995 to August 31st 2017. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. Then meta-analysis was performed by using R statistical software.ResultsA total of thirty-three studies were included. The results of meta-analysis showed the prevalance rate of KOA was 18% (95%CI 14% to 22%), and it was higher in women (19%, 95%CI 16% to 23%) than in men (11%, 95%CI 9% to 13%) (P<0.05). The prevalence rates of KOA in different regions were as follows: 11% (95%CI 8% to 14%) in north, 17% (95%CI 15% to 20%) in north-east, 21% (95%CI 13% to 32%) in east, 21% (95%CI 13% to 33%) in north-west, 22% (95%CI 6% to 57%) in south-west, and 18% (95%CI 13% to 23%) in south-central, respectively.ConclusionsThe prevalence of KOA in China is high, and the disease burden is heavy. Due to the quantity and quality of included studies, more high-quality studies are required to verify the above conclusions in future.
Surgical management of osteoarthritis of the knee: evidence based guideline contains 38 recommendations pertaining to the preoperative, perioperative, and postoperative care of patients with knee osteoarthritis (KOA) who are considering surgical treatment. Compared with the domestic consensus on diagnosis and treatment for KOA, this clinical practice guideline (CPG) prepared by the American Academy of Orthopedic Surgeons (AAOS) has some advantages in terms of methodology selection and recommendation. Therefore, it is necessary for us to interpret this CPG to speed up the understanding and dissemination of the CPG. The ultimate aims are to: ① strengthen the standardization and understanding of surgical treatment of KOA; ② enhance the understanding of clinicians for this CPG in treating KOA; ③ speed up the development of guideline development methodologies in China; ④ provide methodological guidance for the development of CPG based on the current situation in China.
Osteoarthritis research society international (OARSI) guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis in 2019 contained some recommendations in treating patients with osteoarthritis (OA) who are considering non-surgical treatment. Compared with domestic consensus on diagnosis and treatment for OA, this clinical practice guideline (CPG) prepared by OARSI had some advantages in terms of methodology selection and recommendation. Therefore, it is necessary to interpret this CPG to accelerate the understanding and dissemination of the CPG. The ultimate aims were: to strengthen the normative and understanding of non-surgical treatment of OA; to enhance the understanding of clinicians for this CPG in treating OA; to accelerate the development of guideline development methodologies in China; to provide methodological guidance for the development of CPG based on the current situation in China.