Objective To explore the correlation between metabolic syndrome and renal function in physical examination population. Methods The data of individual physical examination in West China Hospital from March to April 2015 was collected. Body mass index (BMI), glomerular filtration rate (GFR) were calculated, and the correlation between metabolic syndrome and renal function was analyzed by using SPSS 16.0 software. Results A total of 10 098 individuals were included, of which 1 110 were MS patients were included. The results of analysis showed that, the levels of uric acid, cholesterol, urea and creatinine in MS group were significantly higher than those in non-MS group, and the level of GFR was significantly lower than that in non-MS group (P < 0.05). Renal function in patients with abnormal systolic blood pressure, diastolic blood pressure, fasting blood glucose (FBG), low density lipoprotein, total cholesterol, triglycerides, uric acid index were significantly higher than those in normal renal function group, and high density lipoprotein cholesterol was significantly lower than that of normal renal function group (P < 0.01). Conclusion Elevated levels of BMI, blood pressure, glucose, uric acid are correlated with the decrease of GFR, and metabolic syndrome is an important risk factor of renal dysfunction.
ObjectiveTo systematically review methodological and reporting quality of systematic reviews/meta-analyses of interventions in the global research field on gliomas. MethodsDatabases including PubMed, EMbase, The Cochrane Library, CNKI and CBM were searched from inception to July 2013, for systematic reviews/meta-analyses of interventions in the research field on gliomas. Two reviewers independently screened literature. Then PRISMA and AMSTAR checklists were used to assess and analysis methodological and reporting quality of included studies. ResultsA total of 51 systematic reviews or meta-analyses were identified. The results showed that the weakness of methodological quality mainly contained lack of study design, incomprehensive of literature search, limited form of included publications, lack of assessing publication bias, lack of reporting of conflict of interest. The weakness of reporting quality included incomplete reporting of literature search, quality assessment, risk of bias and results (some studies lacked forest plots, estimated value of pooled results, 95%CI, and heterogeneity). ConclusionThere are problems at different levels regarding current methodological and reporting quality of systematic reviews/meta-analyses of interventions in the global research field on gliomas. The relevant researchers should improve the scientificity and standardization of systematic reviews/meta-analyses and report them according to the PRISMA statement.