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find Keyword "T分期" 2 results
  • Magnetic Resonance Imaging for The T Staging of Gastric Cancer: A Meta-Analysis

    Object To evaluate the sensitivity, specificity, and accuracy of magnetic resonance imaging (MRI) for the preoperative T staging of gastric cancer. MethodsThe databases such as the PubMed, Cochrane Database Systematic Reviews, EMbase, CNKI, and Wanfang Data were searched on computer from 1993 to 2012.The reviewers screened the trials according to inclusion and exclusion criteria strictly, extracted the data, and assessed the methodology quality.Meta-analysis were performed using the Metadisc 1.40 software, the pathology diagnosis as gold standard.The acquired pooled sensitivity, specificity, and summary receiver operating characteristic curve (SROC) were used to describe the value of MRI in T staging. ResultsEight case-control studies involving 302 patients with gastric cancer were included in the study.The pooled statistical results of Meta-analysis showed that:the pooled sensitivity and specificity of MRI for T1-stage gastric cancer were 85%(55%-98%) and 97%(91%-99%) respectively, and the area under the SROC curve (AUC) was 0.961.The pooled sensitivity and specificity of MRI for T2-stage gastric cancer were 73%(60%-84%) and 93%(89%-96%) respectively, and the AUC was 0.935.The pooled sensitivity and specificity of MRI for T3-stage gastric cancer were 87%(81%-92%) and 82%(74%-88%) respectively, and the AUC was 0.914.The pooled sensitivity and specificity of MRI for T4-stage gastric cancer were 75%(62%-86%) and 97%(94%-99%) respectively, and the AUC was 0.963. ConclusionMRI has the high consistency in preoperative T staging with pathology, and should be recommended as a preferred to increase the accuracy of preoperative staging, and improve the prognosis.

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  • 肿瘤大小对各T分期胃癌患者预后影响的分析

    目的探讨肿瘤大小对各T分期胃癌患者预后的影响。 方法收集535例行根治术胃癌患者的临床资料,采用ROC曲线下面积取截断点,根据肿瘤直径分为<4.5 cm组和≥4.5 cm组。应用Kaplan-Meier生存曲线比较相同T分期中不同肿瘤大小对胃癌患者预后的影响。 结果肿瘤直径<4.5 cm组和≥4.5 cm组患者术后5年累积生存率分别为66.9%和28.3%,其差异有统计学意义(P<0.05)。在T1期患者中,肿瘤直径≥4.5 cm组与<4.5 cm组之间预后差异无统计学意义(P>0.05);在T2及T3期患者中,肿瘤直径≥4.5 cm组和<4.5 cm组之间预后差异有统计学意义(P<0.05);在T4期患者中,肿瘤直径≥4.5 cm组和<4.5 cm组之间预后差异无统计学意义(P>0.05)。 结论肿瘤大小是影响T2及T3期胃癌患者预后的重要因素之一。

    Release date:2016-10-25 06:10 Export PDF Favorites Scan
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