It is difficult to distinguish the inferior alveolar nerve (IAN) from other tissues inside the IAN canal due to their similar CT values in the X image which are smaller than that of the bones. The direct reconstruction, therefore, is difficult to achieve the effects. The traditional clinical treatments mainly rely on doctors' manually drawing the X images so that some subjective results could not be avoided. This paper proposes the partition reconstruction of IAN canal based on shape features. According to the anatomical features of the IAN canal, we divided the image into three parts and treated the three parts differently. For the first, the directly part of the mandibular, we used Shape-driven Level-set Algorithm Restrained by Local Information (BSLARLI) segment IAN canal. For the second part, the mandibular body, we used Space B-spline curve fitting IAN canal's center, then along the center curve established the cross section. And for the third part, the mental foramen, we used an adaptive threshold Canny algorithm to extract IAN canal's edge to find center curve, and then along it established the cross section similarly. Finally we used the Visualization Toolkit (VTK) to reconstruct the CT data as mentioned above. The VTK reconstruction result by setting a different opacity and color values of tissues CT data can perspectively display the INA canal clearly. The reconstruction result by using this method is smoother than that using the segmentation results and the anatomical structure of mental foramen position is similar to the real tissues, so it provides an effective method for locating the spatial position of the IAN canal for implant surgeries.
Integrating visualization toolkit and the capability of interaction, bidirectional communication and graphics rendering which provided by HTML5, we explored and experimented on the feasibility of remote medical image reconstruction and interaction in pure Web. We prompted server-centric method which did not need to download the big medical data to local connections and avoided considering network transmission pressure and the three-dimensional (3D) rendering capability of client hardware. The method integrated remote medical image reconstruction and interaction into Web seamlessly, which was applicable to lower-end computers and mobile devices. Finally, we tested this method in the Internet and achieved real-time effects. This Web-based 3D reconstruction and interaction method, which crosses over internet terminals and performance limited devices, may be useful for remote medical assistant.
ObjectivesTo survey the domestic research situation of evidence-based education through visual studies. To summarize the utilization of education evidence in China and promote the process of evidence-based practice concepts and methods application in social science fields, so as to facilitate the domestic evidence-based research towards more scientific and practical. Methods WanFang Data and CNKI databases were searched to collect evidence-based education literatures from inception to December, 2017. Tableau and UCINET software were used to conduct visual and co-word analysis of study types, regions, staff, time, foundation/government support and key words. The social evidence based research situation was sketched. Results A total of 54 literatures were included. Beijing and Guangdong province published the most literatures, followed by Zhejiang province and Tianjin municipality. The quantity of literatures published in 2014 reached the peak of 11 articles, followed by 2016 and 2017, and relatively few in remaining years. We found that " evidence-based pedagogy” owned the highest frequency through building core keywords matrix. Conclusions Evidence-based education in China is still at an early stage. Introduction and promotion is currently the main content. There exists problems remaining in the development of evidence-based education, for instance disjointedness of theory and practice, regional unbalance, and deficiency of original-research. It is still a long way to go.
ObjectivesTo explore the current situation, hotspots and trends of research on chronic stable angina pectoris in recent 15 years in China, based on bibliometrics, co-occurrence analysis, cluster analysis and visualization analysis.MethodsUsing CNKI database as the source of literature, we collected the related research of chronic stable angina from 2004 to 2018. Citespace software was used to conduct co-occurrence analysis with authors, institutions and keywords as nodes, cluster analysis, time evolution analysis and Burst analysis of keywords, and corresponding visualization maps were drawn and analyzed.ResultsA total of 4 329 related literatures were retrieved, with analysis showing that the focus of research on chronic stable angina pectoris had been developing steadily in recent years, in which the outstanding contribution was represented by Yang guanlin, Liaoning University of Traditional Chinese Medicine and its affiliated hospital. Research hotspots and frontiers had been mainly focused on angina pectoris, coronary heart disease, trimetazidine, clinical research and other aspects.ConclusionsCiteSpace is used to analyze researches on chronic stable angina pectoris published on Chinese journals from full-text databases in recent 15 years, while intuitively represent the general situation of researches on chronic stable angina pectoris in the past 15 years, preliminarily revealing the cooperative researchers and institutions, forming a general understanding of its research hotspots, frontiers and research trends, and providing a reference for the future development direction.
ObjectivesTo investigate and analyze the status of pediatric internal medicine clinical practice guidelines published in journals of mainland China from 2010 to 2017.MethodsCBM, CNKI, VIP and WanFang Data databases were electronically searched to collect pediatric internal medicine clinical practice guidelines published in Chinese journals of mainland China from January 2010 to December 2017. Two reviewers independently screened literature, extracted data. The author's information was organized and co-word matrixes were produced using BICOMS 2 software. The visualization diagram was plotted using Ucinet 6.0 software to analysze the societal relationship of authors.ResultsA total of 135 pediatric clinical guidelines were included, involving 109 western medical guidelines, 24 Chinese traditional medicine guidelines and 2 guidelines on integrated traditional Chinese and western medicine. The main types of clinical practice guidelines for children were diagnosis and treatment (45.19%), followed by technical guidelines (15.56%). Most of the guidelines were on respiratory diseases (23.70%). 54.81% of the guidelines for children were formulated by seminars and consensus, and 28.89% of the guidelines mentioned the application of evidence-based methods to develop guidelines. The institutes (40.00%) were participated in the development of the guidelines, in which 11 research groups were participated in the development of the guidelines.ConclusionsThe quantity of pediatric internal medicine clinical practice guidelines in mainland China has increased from 2010 to 2017. The scope of the guidelines is limited, and cooperation is required to further improve the quality of children’s guidelines.
ObjectivesTo analyze and track the hotspots and frontiers of the field of frailty by analyzing the related research published by SCI-journals in recent decade.MethodsData of publications from 2010 to 2019 were retrieved from the Web of Science Core Collection database. CiteSpace was used to analyze the hotspots and frontiers of frailty research from high-impact countries/regions, institutions, authors, high-frequency keywords and burst terms.ResultsA total of 12 768 publications were identified. The United States was the leading country for publications. Research hotspots focused on adverse health outcomes associated with frailty, interventions, and frailty in elderly patients and females. Besides, frailty assessment and screening, cohort study, meta-analysis and cognitive impairment were the frontier fields.ConclusionsAdverse health outcomes associated with frailty, interventions, and frailty in elderly patients and females are the hotspots and frontiers of frailty research.
ObjectiveTo analyze the hotspots and frontiers of oral lichen planus research by bibliometric methods.MethodsWe searched Web of Science Core Collection database to obtain studies on oral lichen planus from inception to January 1st, 2020. After data extraction, Excel 2016 and CiteSpace software were used to carry out descriptive and visual analysis.ResultsA total of 3 105 articles and reviews were included, and the annual publication volume showed a steady growth trend. The research hotspot terms of oral lichen planus were cancer, lesion, and management of the disease. Moreover, pathogenesis, potentially malignant disorder, classification, and diagnosis were defined as novel research frontiers.ConclusionsThrough the bibliometric method, the research hotspots and frontiers of oral lichen planus are displayed intuitively, which provides references for future research.
Epigenetics refers to the modification effect of external and internal environmental factors on genes under the premise of the unaltered genetic sequence, leading to changes in gene expression level or function, and thereby affecting various phenotypes or disease outcomes. In recent years, epigenetics has attracted increasing attention. Among them, DNA methylation has been shown to be closely related to human development and the development of disease. However, the high-dimensional omics data generated by genome-wide methylation detection can comprehensively reflect the overall and local epigenetic modifications at the genome level, which has become one of the main research contents in this field. Based on genome-wide methylation chip data, this paper summarized the quality control process of this omics data, common epigenetic omics correlation statistical analysis methods and ideas, and visualization realization of main results based on SAS JMP Genomics 10 software, so as to provide reference for similar studies.
Objective To analyze the advancement and trends of English literature on elderly integrated care, and provide a reference for related research and practice in China. Methods Web of Science database was searched for English literature on elderly integrated care published between 1977 and 2000, and then CiteSpace software was applied to analyze and graphically present the articles to understand the chronological development, publishing institutions, research hotspots, key articles and so on. Results A total of 1177 English research papers on elderly integrated care were included. The yearly quantity of articles increased significantly since 2016. More than 100 articles had origin in the Unite State of America, the Netherland, the United Kingdom, and Canada, respectively; the organizations of those researches were mainly single programs, and the research fields were relatively scattered. The high-frequency keywords of these articles were health care, quality of life, primary care, home care, community, chronic disease, long term care, mental health, etc, and the burst terms were long term care, case management, quality of life, community, rehabilitation, telehealth, all inclusive care, etc. According to the centrality of co-citation clustering, the top one article was World Report on Ageing and Health published by the World Health Organization. Conclusions Elderly integrated care has been paid increasing international attention. In recent years, integrated care, transitional care, case management and telecare have become research hotspots. With the key policies of people-centred and integrated health services, primary care, and community-level interventions, typical countries have developed basic models of elderly integrated care. The above theories and experiences can provide references for the practice of elderly integrated care in China.
ObjectiveTo analyze the research status and summarize research hotspots and development trends of research on artificial intelligence in stomatology. MethodsData retrieved from the Web of Science Core Collection database from inception to 2021 were analyzed by CiteSpace software. ResultsThe number of publications about artificial intelligence in stomatology was rising. The United States ranked first in terms of publications and cooperation capabilities. Apart from comprehensive stomatology journals, the literature was mainly published by specialist journals of oral and maxillofacial surgery, orthodontic and dental radiology. Oral head and neck tumors were the frontier field of artificial intelligence research in stomatology. Artificial intelligence, including deep learning and neural networks, showed the tremendous potential medical value and economic value in assisting in the diagnosis and treatment decisions of oral diseases. ConclusionThe research of artificial intelligence in stomatology has rapidly increased, which is conducive to the development of stomatology in the direction of digitalization, intelligence, and individuation.